山茶黄酮苷 A
Camellianin A
|
|
产品编号 |
CFN90992 |
| CAS编号 |
109232-77-1 |
| 分子式 = 分子量 |
C29H32O15 = 620.56 |
| 产品纯度 |
>=98% |
| 物理属性 |
Powder |
| 化合物类型 |
Flavonoids |
| 植物来源 |
The leaves of Adinandra nitida Merr. ex. H.L. Li . |
| ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用 |
|
| 产品名称 |
产品编号 |
CAS编号 |
包装 |
QQ客服 |
| 山茶黄酮苷 A |
CFN90992 |
109232-77-1 |
1mg |
QQ客服：2159513211 |
| 山茶黄酮苷 A |
CFN90992 |
109232-77-1 |
5mg |
QQ客服：2159513211 |
| 山茶黄酮苷 A |
CFN90992 |
109232-77-1 |
10mg |
QQ客服：2159513211 |
| 山茶黄酮苷 A |
CFN90992 |
109232-77-1 |
20mg |
QQ客服：2159513211 |
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ChemFaces的产品在许多优秀和顶级科学期刊中被引用
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
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IF=12.804(2019)PMID: 30417089
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国外学术期刊发表的引用ChemFaces产品的部分文献
| Description: |
Camellianin A has anticancer activity, it can inhibit the proliferation of the human hepatocellular liver carcinoma Hep G2 and human breast adenocarcinoma MCF-7 cell lines in a dose-dependent manner and induce the significant increase of the G0/G1 cell population. Camellianin A also shows angiotensin converting enzyme (ACE) inhibitory activity. |
| Targets: |
ACEI |
| In vitro: |
| Molecules. 2010 May 28;15(6):3878-86. | | Anti-proliferative effect of camellianin A in Adinandra nitida leaves and its apoptotic induction in human Hep G2 and MCF-7 cells.[Pubmed: 20657414 ] | Leaves of Adinandra nitida constitute a kind of flavonoid-rich plant food.
METHODS AND RESULTS:
In this study, camellianin A, the main flavonoid in the leaves of Adinandra nitida,was prepared and identified by high performance liquid chromatography-photodiode array detector-electrospray ionization mass spectrometry (HPLC-PDA-ESI/MS). In the anticancer assay, it was found camellianin A could inhibit the proliferation of the human hepatocellular liver carcinoma Hep G2 and human breast adenocarcinoma MCF-7 cell lines in a dose-dependent manner and induce the significant increase of the G0/G1 cell population. After treated by camellianin A, phosphatidylserine of Hep G2 and MCF-7 cells could translocate significantly to the surface of the membrane. The increase of an early apoptotic population of Hep G2 and MCF-7 cells was observed.
CONCLUSIONS:
It was concluded that camellianin A not only affected the progress of the cell cycle, but also induced cells to enter into apoptosis. |
|
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
1.6114 mL |
8.0572 mL |
16.1145 mL |
32.229 mL |
40.2862 mL |
| 5 mM |
0.3223 mL |
1.6114 mL |
3.2229 mL |
6.4458 mL |
8.0572 mL |
| 10 mM |
0.1611 mL |
0.8057 mL |
1.6114 mL |
3.2229 mL |
4.0286 mL |
| 50 mM |
0.0322 mL |
0.1611 mL |
0.3223 mL |
0.6446 mL |
0.8057 mL |
| 100 mM |
0.0161 mL |
0.0806 mL |
0.1611 mL |
0.3223 mL |
0.4029 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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