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  • 黄芩素 7-O-beta-D-葡萄糖醛酸乙酯

    • 黄芩素 7-O-beta-D-葡萄糖醛酸乙酯

    Baicalein 7-O-beta-D-ethylglucuronide

    黄芩素 7-O-beta-D-葡萄糖醛酸乙酯
    		产品编号 CFN91993
    CAS编号 675624-38-1
    分子式 = 分子量 C23H22O11 = 474.41
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Flavonoids
    植物来源 The roots of Scutellaria baicalensis Georgi
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    黄芩素 7-O-beta-D-葡萄糖醛酸乙酯 CFN91993 675624-38-1 1mg QQ客服：1457312923
    黄芩素 7-O-beta-D-葡萄糖醛酸乙酯 CFN91993 675624-38-1 5mg QQ客服：1457312923
    黄芩素 7-O-beta-D-葡萄糖醛酸乙酯 CFN91993 675624-38-1 10mg QQ客服：1457312923
    黄芩素 7-O-beta-D-葡萄糖醛酸乙酯 CFN91993 675624-38-1 20mg QQ客服：1457312923
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学，并且还在增涨
  • University of Leipzig (Germany)
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  • Monash University (Australia)
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    • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Hum Exp Toxicol.2017, 36(11):1169-1176
  • Environ Toxicol.2023, 38(7):1641-1650.
  • Antioxidants (Basel).2023, 13(1):12.
  • Chinese J of Tissue Engineering Res.2022, 26(17): 2636-2641.
  • Processes2020, 8(12),1540.
  • Asian Pac J Cancer Prev.2021, 22(S1):97-106.
  • Postharvest Biol Tec2019, 149:18-26
  • Pharmacognosy Journal, 2021, 13(5).
  • Anticancer Res.2014, 34(7):3505-9
  • Sustainable Chemistry & Pharmacy2022, 30:100883.
  • Phytomedicine.2018, 38:45-56
  • J Ethnopharmacol.2022, 289:115018.
  • Research Square2022, rs.3.rs-1948239
  • Cells.2022, 11(6):931.
  • VNU Journal of Science: Med.& Pharm. Sci.2022, 38(2):2588-1132.
  • Ecol Evol.2022, 12(11):e9459.
  • Molecules. 2013, 18(7):7376-88
  • VNU Journal of Science2023, 39(2):24-33.
  • Processes2021, 9(5),831.
  • J Pharm Biomed Anal.2017, 140:274-280
  • J Control Release.2021, 336:159-168.
  • Phytomedicine.2021, 93:153789.
  • Materials Today Communications2023, 37:107216
  • ...
    • 生物活性
    Description: Baicalein 7-O-beta-D-ethylglucuronide is a natural product from Scutellaria baicalensis Georgi.
    In vitro:
    Nat Prod Res. 2014;28(20):1772-6.
    A new antioxidant flavone glycoside from Scutellaria baicalensis Georgi.[Pubmed: 24995563 ]

    METHODS AND RESULTS:
    A new flavone glycoside, wogonin 7-O-β-D-ethylglucuronide (1), together with a new natural flavone glycoside baicalein 7-O-β-D-ethylglucuronide (Baicalein 7-O-beta-D-ethylglucuronide,2) and four known analogues, wogonoside (3), wogonin (4), oroxylin A 7-O-β-D-methylglucuronide (5) and oroxylin A (6), was isolated from the roots of Scutellaria baicalensis Georgi. The structure elucidation of the new compound was primarily based on HR-ESI-MS, 1D and 2D NMR analyses.
    CONCLUSIONS:
    Compounds 1 and 3 inhibited FeSO4-Cys-induced liver homogenate lipid peroxidation with IC50 at 18.2 μM and 24.9 μM, respectively, and exhibited strong cytoprotective effects against H2O2-induced oxidative damage in human umbilical vein endothelial cells at low concentrations of 10.0 μM and 3.0 μM.
    In vivo:
    Journal of Applied Pharmaceutical Science, 2013, 3(12):46-51.
    Evaluation of wound healing activity of baicalein-7-O- β-Dglucuronide isolated from Leucas aspera[Reference: WebLink]
    Leucas aspera (Willd.) Linn. (Lamiaceae), commonly known as "Thumbai," is distributed throughout India. This study includes the isolation and characterization of flavonoids present in Leucas aspera flowers were compared wound healing activity with standard soframycin ointment.
    METHODS AND RESULTS:
    The plant materials were extracted with 95% methanol, petroleum ether, ethyl acetate, and were subjected to column and TLC chromatographic separation analysis. The chemical constituents isolated from the flowers of L. aspera were characterized based on chemical tests and spectral analysis such as UV and NMR spectroscopy. The structure of the isolated compound was confirmed as baicalein-7-O- β-D-glucuronide (baicalin). It has been investigated for wound healing activity by applying on the albino rats. A slow rate of healing was observed earlier which turns to very rapid on the 12th day. The histopathological examination provided additional evidence for the experimental wound healing studies. Protease is a biochemical marker and pH measured to support the wound healing activity.
    CONCLUSIONS:
    We conclude that the baicalin isolated with the flowers of L. aspera has better wound healing activity.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.1079 mL 10.5394 mL 21.0788 mL 42.1576 mL 52.697 mL
    5 mM 0.4216 mL 2.1079 mL 4.2158 mL 8.4315 mL 10.5394 mL
    10 mM 0.2108 mL 1.0539 mL 2.1079 mL 4.2158 mL 5.2697 mL
    50 mM 0.0422 mL 0.2108 mL 0.4216 mL 0.8432 mL 1.0539 mL
    100 mM 0.0211 mL 0.1054 mL 0.2108 mL 0.4216 mL 0.527 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    黄芩素 7-O-beta-D-葡萄糖醛酸乙酯; Baicalein 7-O-beta-D-ethylglucuronide CFN91993 675624-38-1 C23H22O11 = 474.41 5mg QQ客服：1413575084
    黄芩素 6-O-葡萄糖苷; Baicalein 6-O-glucoside CFN92361 28279-72-3 C21H20O10 = 432.4 5mg QQ客服：1413575084
    木蝴蝶苷B; Oroxin B CFN99713 114482-86-9 C27H30O15 = 594.52 20mg QQ客服：2159513211
    千层纸素A-7-0-β-D-葡萄糖醛酸苷; Oroxylin A 7-O-beta-D-glucuronide CFN90191 36948-76-2 C22H20O11 = 460.39 20mg QQ客服：1457312923
    千层纸素A-7-0-β-D-葡萄糖醛酸苷甲酯; Oroxylin A 7-O-beta-D-glucuronide methyl ester CFN92282 82475-01-2 C23H22O11 = 474.4 5mg QQ客服：2159513211
    Glychionide A; Glychionide A CFN92280 119152-50-0 C21H18O11 = 446.4 5mg QQ客服：1413575084
    去甲汉黄芩素-8-O-葡萄糖醛酸苷; Norwogonin-8-O-glucuronide CFN95423 118525-47-6 C21H18O11 = 446.4 5mg QQ客服：1457312923
    汉黄芩苷; Wogonoside CFN99710 51059-44-0 C22H20O11 = 460.39 20mg QQ客服：215959384
    穿心莲黄酮苷C; Andrographidine C CFN97852 113963-39-6 C23H24O10 = 460.44 5mg QQ客服：215959384
    5-Hydroxy-7,8-dimethoxy (2R)-flavanone-5-O-beta-D-glucopyranoside; 5-Hydroxy-7,8-dimethoxy (2R)-flavanone-5-O-beta-D-glucopyranoside CFN95209 942626-74-6 C23H26O10 = 462.5 10mg QQ客服：2056216494

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