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  • 黄芪皂苷III

    Astragaloside III

    黄芪皂苷III
    产品编号 CFN99174
    CAS编号 84687-42-3
    分子式 = 分子量 C41H68O14 = 784.97
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Triterpenoids
    植物来源 The roots of Astragalus membranaceus (Fisch.) Bunge
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    黄芪皂苷III CFN99174 84687-42-3 10mg QQ客服:2056216494
    黄芪皂苷III CFN99174 84687-42-3 20mg QQ客服:2056216494
    黄芪皂苷III CFN99174 84687-42-3 50mg QQ客服:2056216494
    黄芪皂苷III CFN99174 84687-42-3 100mg QQ客服:2056216494
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Universitas Airlangga (Indonesia)
  • Hamdard University (India)
  • Helmholtz Zentrum München (Germany)
  • Institute of Chinese Materia Medica (China)
  • Osmania University (India)
  • Max Rubner-Institut (MRI) (Germany)
  • Calcutta University (India)
  • University of Auckland (New Zealand)
  • Institute of Pathophysiology Medical University of Vienna (Austria)
  • Universidade de Franca (Brazil)
  • Sri Sai Aditya Institute of Pharmaceutical Sciences and Research (India)
  • University of Maryland (USA)
  • Aarhus University (Denmark)
  • Universidade da Beira Interior (Germany)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • J Agric Food Chem.2024, acs.jafc.4c01387.
  • J Ethnopharmacol.2019, 241:112025
  • J Biomol Struct Dyn.2023, 1-21.
  • Biol Pharm Bull.2018, 41(11):1645-1651
  • Environ Toxicol.2020, doi: 10.1002
  • Bioorg Med Chem.2018, 26(14):4201-4208
  • J Pharm Biomed Anal.2019, 172:268-277
  • Biol Pharm Bull.2021, 44(12):1891-1893.
  • Genes Genomics.2020, 10.1007
  • Academic J of Second Military Medical University2018, 39(11)
  • Vietnam Journal of Science2022, 64(2), 69-75.
  • Nutrients.2018, 10(12)
  • Academic J of Second Military Medical University2019, 40(1)
  • Industrial Crops and Products2018, 353-362
  • Plants (Basel).2021, 10(11):2317.
  • Malaysian Journal of Analytical Sciences2023, 27(4):840-848.
  • Molecules.2022, 27(21):7514.
  • J Pharmacopuncture.2023, 26(4):357-365.
  • Front Pharmacol.2022, 13:870553.
  • Molecules.2024, 29(6):1240.
  • Nutrients.2018, 10(12):E1998
  • J Immunol.2023, ji2200727.
  • Food Sci Nutr.2023, 11(9):5532-5542.
  • ...
  • 生物活性
    Description: Astragaloside III has anti-gastric ulcer effects, and exhibits strong growth-promoting effects in cultured GES-1 cells. Astragaloside III can effectively reduce cancer cell survival in vitro and inhibit the tumor growth in vivo, the potential mechanism is the induction of cell apoptosis signaling pathways, suggests that it provides a new therapeutic tool to treat breast cancer.
    In vitro:
    Fitoterapia. 2010 Jul;81(5):447-51.
    Effects of cycloartane saponins from hairy roots of Astragalus membranaceus Bge., on human tumor cell targets.[Pubmed: 20060881]
    For the first time three different natural compounds, isolated from hairy roots of Astragalus membranaceus, cultivated in airlift bioreactor were tested for their cytotoxic potential and apoptosis induction in a panel of human tumor cell lines.
    METHODS AND RESULTS:
    Root cultures, cultivated in bioreactor gave 18.5 g l(-1) dry wt roots with the highest astragaloside production in vitro up to now - 1.64% (astragaloside I), 1.12% (astragaloside II) and 1.08% (astragaloside III).
    CONCLUSIONS:
    In this manner the production in airlift bioreactor can be used as means of reliable supply of cycloartane saponins to extend the research to human clinical studies.
    In vivo:
    Afr. J. Tradit. Complem., 2015, 12(3):183-6.
    Astragaloside III from Astragalus membranaceus antagonizes breast cancer growth[Reference: WebLink]
    Astragaloside III has been used to treat different cancers; however their effect on breast cancer remains unknown.
    METHODS AND RESULTS:
    The present study examined the effects of Astragaloside III from Astragalus membranaceus on breast cancer cell lines in vitro as well as xenograft in vivo. The results showed that the Astragaloside III could effectively reduce cancer cell survival in vitro and inhibit the tumor growth in vivo. The potential mechanism is the induction of cell apoptosis signaling pathways.
    CONCLUSIONS:
    We believe that Astragaloside III provides a new therapeutic tool to treat breast cancer.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.2739 mL 6.3697 mL 12.7393 mL 25.4787 mL 31.8484 mL
    5 mM 0.2548 mL 1.2739 mL 2.5479 mL 5.0957 mL 6.3697 mL
    10 mM 0.1274 mL 0.637 mL 1.2739 mL 2.5479 mL 3.1848 mL
    50 mM 0.0255 mL 0.1274 mL 0.2548 mL 0.5096 mL 0.637 mL
    100 mM 0.0127 mL 0.0637 mL 0.1274 mL 0.2548 mL 0.3185 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    环黄芪醇; Cycloastragenol CFN99538 84605-18-5 C30H50O5 = 490.71 20mg QQ客服:1457312923
    黄芪甲苷IV; 黄芪皂苷Ⅳ; 黄芪甲苷; 黄芪甲甙; Astragaloside IV CFN99171 84687-43-4 C41H68O14 = 784.98 20mg QQ客服:1457312923
    黄芪甲苷 VII; Astrasieversianin VII CFN90648 86764-11-6 C43H70O15 = 827.01 10mg QQ客服:1457312923
    黄芪皂苷II; Astragaloside II CFN99173 84676-89-1 C43H70O15 = 827.02 20mg QQ客服:1457312923
    黄芪皂苷I; Astragaloside I CFN99172 84680-75-1 C45H72O16 = 869.1 20mg QQ客服:2159513211
    异黄芪皂苷I; Isoastragaloside I CFN90977 84676-88-0 C45H72O16 = 869.1 10mg QQ客服:2056216494
    黄芪皂苷III; Astragaloside III CFN99174 84687-42-3 C41H68O14 = 784.97 20mg QQ客服:2056216494
    黄肉楠碱; Actein CFN99864 18642-44-9 C37H56O11 = 676.9 5mg QQ客服:215959384
    升麻素苷; Cimicifugoside CFN90481 66176-93-0 C37H54O11 = 674.81 5mg QQ客服:2056216494
    26-脱氧升麻苷; 26-Deoxycimicifugoside CFN90788 214146-75-5 C37H54O10 = 658.8 5mg QQ客服:1457312923

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