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  • 26-脱氧升麻苷

    26-Deoxycimicifugoside

    26-脱氧升麻苷
    产品编号 CFN90788
    CAS编号 214146-75-5
    分子式 = 分子量 C37H54O10 = 658.8
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Triterpenoids
    植物来源 The rhizomes of Cimicifuga foetida L.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    26-脱氧升麻苷 CFN90788 214146-75-5 1mg QQ客服:2056216494
    26-脱氧升麻苷 CFN90788 214146-75-5 5mg QQ客服:2056216494
    26-脱氧升麻苷 CFN90788 214146-75-5 10mg QQ客服:2056216494
    26-脱氧升麻苷 CFN90788 214146-75-5 20mg QQ客服:2056216494
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Imperial College London (United Kingdom)
  • Sanford Burnham Prebys Medical Discovery Institute (USA)
  • University of Ioannina (Greece)
  • University of Parma (Italy)
  • Donald Danforth Plant Science Center (USA)
  • Universidad Veracuzana (Mexico)
  • University of Stirling (United Kingdom)
  • Sri Sai Aditya Institute of Pharmaceutical Sciences and Research (India)
  • Ain Shams University (Egypt)
  • Periyar University (India)
  • Harvard University (USA)
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  • University of Toulouse (France)
  • Universidade do Porto (Portugal)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Biochem Biophys Res Commun.2020, 530(1):4-9.
  • Biomedicine & Pharmacotherapy2022, 153:113404.
  • Inflammation.2020, 43(5):1716-1728.
  • Turk J Med Sci.2023 53: 1312-1320.
  • Environ Toxicol.2022, 37(3):514-526.
  • Molecules2022, 27(14),4462
  • Front Pharmacol.2023, 14:1244655.
  • Chem. of Vegetable Raw Materials2020, 97-105
  • Fitoterapia.2021, 153:104995.
  • Chung Shan Medical University2020, US20200323790A1
  • Cell Mol Biol(Noisy-le-grand)2019, 65(7):77-83
  • Universitat Stuttgart2022, opus-12200.
  • Applied Biological Chemistry2020, 63:37.
  • Pharmacological Reports2020, 1-9
  • Int J Mol Sci.2018, 19(9):E2601
  • J Ethnopharmacol.2020, 260:112988.
  • Tropical Journal of Pharmaceutical Research 2021, 20(6):1165-1170.
  • Korean J. Medicinal Crop Sci.2022, 30(2):124-133
  • Plants (Basel).2021, 10(6):1119.
  • BMC Complement Altern Med.2017, 17(1):384
  • Journal of Plant Growth Regulation2022, 10705-2.
  • Molecules.2021, 26(16):4722.
  • Life Sci.2018, 209:498-506
  • ...
  • 生物活性
    Description: 26-Deoxycimicifugoside is a natural product from Cimicifuga foetida L.
    In vitro:
    Periodical of Ocean University of China, 2014 , 44 (11) :74-80.
    Cycloartane Triterpenoid Saponins from Cimicifuga foetida and Their Cytotoxic Activity[Reference: WebLink]

    METHODS AND RESULTS:
    Fifteen cycloartane saponins(1-15)were isolated from EtOAc fraction of EtOH extracts of the C.foetidarhizoma using silicon chromatography methods.And comparison their spectroscopic data with those of literatures allowed these compounds to be identified as 25-anhydrocimigenol-3-O-β-D-xylopyranoside(1),25-O-acetyl-cimigenol-3-O-β-D-xylopyranoside(2),25-O-acetyl-7,8-didehydrocimigenol-3-O-β-D-xylopyranoside(3),25-O-acetyl-cimigenol-3-O-α-L-arabinopyranoside(4),asiaticoside A(5),asiaticoside B(6),isocimipodocarpaside(7),cimicidanol(8),26-Deoxyactein(9),cimigenol-3-O-β-D-xylopyranoside(10),24-O-acetylisodahurinol-3-O-β-D-xylopyranoside(11),23-O-acetylshengmanol-3-O-β-D-xylopyranoside(12),26-Deoxycimicifugoside(13),cimicifugoside H-1(14),and cimicifugoside H-2(15).
    CONCLUSIONS:
    Compound 6 was isolated from this genus for the first time,and compounds 3,7and 11 were firstly isolated from the species. Additionally,compounds 2-6 showed potent cytotoxicities against the selected HeLa and MCF-7cancer cell lines with IC50 values ranging from 7.25-23.61μM.The present research further enriches chemodiveristy of the traditional medicine of C.foetida,and provides the potential structure activity relationship.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.5179 mL 7.5896 mL 15.1791 mL 30.3582 mL 37.9478 mL
    5 mM 0.3036 mL 1.5179 mL 3.0358 mL 6.0716 mL 7.5896 mL
    10 mM 0.1518 mL 0.759 mL 1.5179 mL 3.0358 mL 3.7948 mL
    50 mM 0.0304 mL 0.1518 mL 0.3036 mL 0.6072 mL 0.759 mL
    100 mM 0.0152 mL 0.0759 mL 0.1518 mL 0.3036 mL 0.3795 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    土荆皮内酯B; Pseudolarolide B CFN91878 151368-43-3 C30H42O4 = 466.65 5mg QQ客服:215959384
    升麻内酯A; Cimilactone A CFN92971 468733-06-4 C33H50O9 = 590.74 5mg QQ客服:2056216494
    21,24-环氧基环安坦-3,25-二醇; 21,24-Epoxycycloartane-3,25-diol CFN97836 125305-73-9 C30H50O3 = 458.73 5mg QQ客服:3257982914
    环黄芪醇; Cycloastragenol CFN99538 84605-18-5 C30H50O5 = 490.71 20mg QQ客服:1413575084
    黄芪甲苷IV; 黄芪皂苷Ⅳ; 黄芪甲苷; 黄芪甲甙; Astragaloside IV CFN99171 84687-43-4 C41H68O14 = 784.98 20mg QQ客服:2056216494
    黄芪甲苷 VII; Astrasieversianin VII CFN90648 86764-11-6 C43H70O15 = 827.01 10mg QQ客服:215959384
    黄芪皂苷II; Astragaloside II CFN99173 84676-89-1 C43H70O15 = 827.02 20mg QQ客服:1413575084
    黄芪皂苷I; Astragaloside I CFN99172 84680-75-1 C45H72O16 = 869.1 20mg QQ客服:1413575084
    异黄芪皂苷I; Isoastragaloside I CFN90977 84676-88-0 C45H72O16 = 869.1 10mg QQ客服:1457312923
    黄芪皂苷III; Astragaloside III CFN99174 84687-42-3 C41H68O14 = 784.97 20mg QQ客服:2056216494

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