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  • 白桑八醇

    Alboctalol

    白桑八醇
    产品编号 CFN97075
    CAS编号 62394-00-7
    分子式 = 分子量 C28H24O8 = 488.5
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Phenols
    植物来源 The herbs of Cudrania tricuspidata
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    白桑八醇 CFN97075 62394-00-7 1mg QQ客服:3257982914
    白桑八醇 CFN97075 62394-00-7 5mg QQ客服:3257982914
    白桑八醇 CFN97075 62394-00-7 10mg QQ客服:3257982914
    白桑八醇 CFN97075 62394-00-7 20mg QQ客服:3257982914
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Toronto (Canada)
  • Wroclaw Medical University (Poland)
  • Universiti Malaysia Pahang (Malaysia)
  • University of Sao Paulo (Brazil)
  • Yale University (USA)
  • Kitasato University (Japan)
  • Nicolaus Copernicus Uniwersity (Poland)
  • Universidade Católica Portuguesa (Portugal)
  • Universidade Federal de Pernambuco (UFPE) (Brazil)
  • Fraunhofer-Institut für Molekularbiologie und Angewandte ?kologie IME (Germany)
  • Sri Sai Aditya Institute of Pharmaceutical Sciences and Research (India)
  • University of Brasilia (Brazil)
  • Washington State University (USA)
  • Instituto de Investigaciones Agropecuarias (Chile)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Fitoterapia.2022, 105141.
  • Plant Foods Hum Nutr.2020, 10.1007
  • Biosci. Rep.2020, 10.1024
  • Molecules.2015, 20(10):19172-88
  • J Food Sci.2022, 87(11):4905-4916.
  • Int J Mol Sci.2020, 21(6):2190.
  • J Nat Med.2017, 71(2):380-388
  • J Nat Med.2021, doi: 10.1007.
  • Appl. Sci.2023, 13(17), 9653.
  • Ann Transl Med.2019, 7(23):731
  • Dicle Tip Dergisi2020, 47(2),423-430.
  • J Enzyme Inhib Med Chem.2019, 34(1):134-143
  • Processes2021, 9(5),831.
  • J.Pharm. & Biome. Anal.2023, 2: 100018.
  • J Agric Food Chem.2016, 64(35):6783-90
  • China Pharmacy2015, 26(27)
  • Evid Based Complement Alternat Med.2020, 2020:2584783.
  • Wageningen University & Research2018, January 2018
  • Int J Mol Sci.2022, 23(11):6104.
  • Food Quality and Safety2018, 2:213-219
  • Phytomedicine.2022, 100:154058.
  • Biochem Biophys Res Commun.2020, 530(1):4-9.
  • Biochemical Systematics and Ecology2018, 81
  • ...
  • 生物活性
    Description: Alboctalol inhibits mushroom tyrosinase activity.
    In vitro:
    Phytochemistry. 2015 Jul 15;117:424-435.
    Chemical constituents derived from Artocarpus xanthocarpus as inhibitors of melanin biosynthesis.[Pubmed: 26188915]

    METHODS AND RESULTS:
    Twenty-four compounds, including the previously unknown artoxanthocarpuone A, artoxanthocarpuone B, hydroxylakoochin A, methoxylakoochin A, epoxylakoochin A, and artoxanthol, were isolated and characterized spectroscopically. Among them, artoxanthol is stilbene oligomer presumably constructed in a 5,11,12-triphenyl hexahydrochrysene scaffold by a Diels-Alder type of reaction, for which a biosynthetic pathway is proposed. Artoxanthol, Alboctalol, steppogenin, norartocarpetin, resveratrol, oxyresveratrol, and chlorophorin potently inhibited mushroom tyrosinase activity with IC50 values from 0.9 to 5.7μM that were all far stronger than the positive controls. Artoxanthocarpuone A, artoxanthocarpuone B, methoxylakoochin A, lakoochin A, cudraflavone C, artonin A, resveratrol, and chlorophorin reduced tyrosinase activity and inhibited α-melanocyte-stimulating hormone-induced melanin production in B16F10 melanoma cells without affecting cell proliferation.
    CONCLUSIONS:
    Collectively, the results suggest that the constituents of Artocarpus xanthocarpus have potential to be used as depigmentation agents.
    Z Naturforsch C. 2008 Jan-Feb;63(1-2):35-9.
    Phenolic constituents from the wood of Morus australis with cytotoxic activity.[Pubmed: 18386485]

    METHODS AND RESULTS:
    A new methylated flavonol, 5,7,2',4'-tetrahydroxy-3-methoxyflavone (1), had been isolated from the methanol extract of the wood of Morus australis, along with nine known compounds, kuwanon C (2), morusin (3), morachalcone A (4), oxyresveratrol (5), 4'-(2-methyl-2-buten-4-yl)oxyresveratrol (6), moracins M (7) and C (8), alboctalol (9), and macrourin B (10). The structures of these compounds were determined based on spectral evidence, including UV, IR, NMR, and mass spectra. Cytotoxic properties of compounds 1-10 were evaluated against murine leukemia P-388 cells.
    CONCLUSIONS:
    The prenylated stilbene 6 and 2-arylbenzofuran 8, and morusin (3) were found to have strong cytotoxic effects with IC50 values of 6.9, 8.7, and 10.1 microM, respectively.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.0471 mL 10.2354 mL 20.4708 mL 40.9417 mL 51.1771 mL
    5 mM 0.4094 mL 2.0471 mL 4.0942 mL 8.1883 mL 10.2354 mL
    10 mM 0.2047 mL 1.0235 mL 2.0471 mL 4.0942 mL 5.1177 mL
    50 mM 0.0409 mL 0.2047 mL 0.4094 mL 0.8188 mL 1.0235 mL
    100 mM 0.0205 mL 0.1024 mL 0.2047 mL 0.4094 mL 0.5118 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    射干素B; Shegansu B CFN92424 291535-65-4 C30H26O8 = 514.5 5mg QQ客服:2056216494
    双异丹叶大黄素A; Bisisorhapontigenin A CFN92592 865474-98-2 C31H28O8 = 528.6 5mg QQ客服:1457312923
    Pallidol; Pallidol CFN92341 105037-88-5 C28H22O6 = 454.5 10mg QQ客服:1413575084
    Gnetulin; Gnetulin CFN92444 152340-24-4 C30H26O8 = 514.5 5mg QQ客服:3257982914
    Leachianol G; Leachianol G CFN95146 164204-62-0 C28H24O7 = 472.5 5mg QQ客服:2056216494
    Leachianol F; Leachianol F CFN95147 164123-50-6 C28H24O7 = 472.5 5mg QQ客服:1413575084
    蛇葡萄素F; Ampelopsin F CFN92340 151487-08-0 C28H22O6 = 454.5 5mg QQ客服:2056216494
    Ampelopsin G; Ampelopsin G CFN95148 151487-09-1 C42H32O9 = 680.7 5mg QQ客服:1457312923
    白桑八醇; Alboctalol CFN97075 62394-00-7 C28H24O8 = 488.5 5mg QQ客服:2056216494
    葡萄素; Viniferin CFN92854 253435-07-3 C28H22O6 = 454.1 5mg QQ客服:215959384

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