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  • 15-甲氧基二去氢松香酸

    Abiesadine N

    15-甲氧基二去氢松香酸
    产品编号 CFN99263
    CAS编号 1159913-80-0
    分子式 = 分子量 C21H30O3 = 330.5
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Diterpenoids
    植物来源 The barks of Pinus yunnanensis
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    15-甲氧基二去氢松香酸 CFN99263 1159913-80-0 1mg QQ客服:215959384
    15-甲氧基二去氢松香酸 CFN99263 1159913-80-0 5mg QQ客服:215959384
    15-甲氧基二去氢松香酸 CFN99263 1159913-80-0 10mg QQ客服:215959384
    15-甲氧基二去氢松香酸 CFN99263 1159913-80-0 20mg QQ客服:215959384
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Int J Med Sci.2020, 17(5):626-631
  • Med Sci Monit.2019, 25:9499-9508
  • Food Res Int.2020, 133:109130.
  • J Pharmaceutical Research Int.2021, 33(41A):275-284.
  • Biomolecules.2020, 10(2):E184
  • Nutraceuticals2022, 2(3),150-161
  • Molecules2022, 27(9):2992.
  • Int J Mol Sci.2021, 22(17):9400.
  • Molecules.2021, 26(13):4081.
  • Pharm Biol.2016, 54(7):1255-62
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  • Int Immunopharmacol.2022, 106:108603.
  • Pharmacognosy Magazine2017, 13(52):868-874
  • Food Res Int.2022, 157:111207.
  • J Ethnopharmacol.2018, 210:88-94
  • Int J Biol Macromol.2020, 169:342-351
  • African J. Agricultural Research 2017, 12(13):1164-1168
  • Appl. Sci.2020, 10,1304
  • Oncotarget.2016, 8(51):88386-88400
  • Appl. Sci.2021, 11(24),12080
  • The Journal of Internal Korean Medicine2015, 36(4):486-497
  • J Sci Food Agric.2017, 97(5):1656-1662
  • Biomedicines.2022, 10(2):463.
  • ...
  • 生物活性
    Description: Reference standards.
    In vitro:
    Bioorganic & medicinal chemistry, 2010, 18(2):744-754.
    Isolation, structure, and bioactivities of abiesadines A–Y, 25 new diterpenes from Abies georgei Orr.[Reference: WebLink]

    METHODS AND RESULTS:
    Twenty-five new (abiesadines A–Y, 1–25, abiesadine N) and 29 known (26–54) diterpenes were isolated from the aerial parts of Abies georgei. Abiesadine A (1) is a novel 8,14-seco-abietane, while abiesadine B (2) is a novel 9,10-seco-abietane. The structures of the new compounds were established on the basis of spectroscopic data analysis.
    CONCLUSIONS:
    Manool (52) showed the strongest effect against LPS-induced NO production in RAW264.7 macrophages with the IC50 value of 11.0 μg/mL. In another anti-inflammatory assay against TNFα-triggered NF-κB activity, (12R,13R)-8,12-epoxy-14-labden-13-ol (54) exhibited the strongest effect (IC50 = 8.7 μg/mL). For antitumor assays, pomiferin A (26) and 8,11,13-abietatriene-7α,18-diol (29) both showed the most significant activity against LOVO cells (IC50 = 9.2 μg/mL). While 7-oxocallitrisic acid (46) exhibited significant cytotoxicity against QGY-7703 tumor cells (IC50 = 10.2 μg/mL).
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.0257 mL 15.1286 mL 30.2572 mL 60.5144 mL 75.643 mL
    5 mM 0.6051 mL 3.0257 mL 6.0514 mL 12.1029 mL 15.1286 mL
    10 mM 0.3026 mL 1.5129 mL 3.0257 mL 6.0514 mL 7.5643 mL
    50 mM 0.0605 mL 0.3026 mL 0.6051 mL 1.2103 mL 1.5129 mL
    100 mM 0.0303 mL 0.1513 mL 0.3026 mL 0.6051 mL 0.7564 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    脱氢枞酸; 脱氢松香酸; Dehydroabietic acid CFN99822 1740-19-8 C20H28O2 = 300.4 20mg QQ客服:3257982914
    7-氧代去氢松香酸; 7-Oxodehydroabietic acid CFN95411 18684-55-4 C20H26O3 = 314.4 5mg QQ客服:215959384
    15-羟基脱氢枞酸; 15-Hydroxydehydroabietic acid CFN98906 54113-95-0 C20H28O3 = 316.4 5mg QQ客服:1413575084
    15-甲氧基二去氢松香酸; Abiesadine N CFN99263 1159913-80-0 C21H30O3 = 330.5 5mg QQ客服:2932563308
    7alpha,15-二羟基脱氢枞酸; 7alpha,15-Dihydroxydehydroabietic acid CFN89394 155205-64-4 C20H28O4 = 332.43 5mg QQ客服:2932563308
    15-羟基-7-氧代去氢松香酸; 15-Hydroxy-7-oxodehydroabietic acid CFN97533 95416-25-4 C20H26O4 = 330.4 5mg QQ客服:215959384
    7,15-二羟基脱氢枞酸甲酯; Methyl 7,15-dihydroxydehydroabietate CFN99654 155205-65-5 C21H30O4 = 346.5 5mg QQ客服:1413575084
    7beta,15-二羟基脱氢枞酸甲酯; Methyl 7beta,15-dihydroxydehydroabietate CFN96967 107752-10-3 C21H30O4 = 346.46 5mg QQ客服:2159513211
    15-羟基-7-氧代去氢松香酸甲酯; Methyl 15-hydroxy-7-oxodehydroabietate CFN89396 60188-95-6 C21H28O4 = 344.44 5mg QQ客服:1413575084
    19-O-beta-D-carboxyglucopyranosyl-12-O-beta-D-glucopyranosyl-11,16-dihydroxyabieta-8,11,13-triene; 19-O-beta-D-carboxyglucopyranosyl-12-O-beta-D-glucopyranosyl-11,16-dihydroxyabieta-8,11,13-triene CFN95217 1011714-20-7 C32H48O15 = 672.7 5mg QQ客服:1413575084

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