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  • 3beta-乙酰氧基-11alpha,12alpha-环氧齐墩果烷-13beta,28-内酯

    3beta-Acetoxy-11alpha,12alpha-epoxyoleanan-28,13beta-olide

    3beta-乙酰氧基-11alpha,12alpha-环氧齐墩果烷-13beta,28-内酯
    产品编号 CFN96374
    CAS编号 35738-25-1
    分子式 = 分子量 C32H48O5 = 512.7
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Triterpenoids
    植物来源 The branches of Eysenhardtia platycarpa.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    3beta-乙酰氧基-11alpha,12alpha-环氧齐墩果烷-13beta,28-内酯 CFN96374 35738-25-1 1mg QQ客服:3257982914
    3beta-乙酰氧基-11alpha,12alpha-环氧齐墩果烷-13beta,28-内酯 CFN96374 35738-25-1 5mg QQ客服:3257982914
    3beta-乙酰氧基-11alpha,12alpha-环氧齐墩果烷-13beta,28-内酯 CFN96374 35738-25-1 10mg QQ客服:3257982914
    3beta-乙酰氧基-11alpha,12alpha-环氧齐墩果烷-13beta,28-内酯 CFN96374 35738-25-1 20mg QQ客服:3257982914
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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  • St. Jude Children Research Hospital (USA)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Sci Rep.2016, 6:25094
  • Biomolecules.2021, 11(10):1537.
  • The Japan Society for Analytical Chemistry2018, 67(4):201-206
  • Molecules.2021, 26(2):E255.
  • Chem. of Vegetable Raw Materials2020, 97-105
  • J-STAGE2015, 249-255
  • J Appl Biol Chem.2021, 64(3),263?268
  • Biochem Pharmacol.2017, 130:10-20
  • J Pharm Biomed Anal.2024, 241:115990.
  • Molecules.2017, 22(2)
  • Eur J Pharmacol.2021, 906:174220.
  • Molecules.2022, 27(7):2116.
  • Molecules.2023, 28(13):4972.
  • ACS Pharmacol Transl Sci.2024, 7(2):395-405.
  • Nutrients.2023, 15(12):2644.
  • Universidade Estadual Paulista2017, 11449
  • Journal of Ginseng Research2024, 03.005.
  • Nat Prod Commun.2018, 10.1177
  • Pharmaceuticals (Basel).2024 Feb 24;17(3):292.
  • Exp Parasitol.2015, 153:160-4
  • Cells.2022, 11(8), 1311.
  • Environ Toxicol.2021, 36(9):1848-1856.
  • Int J Nanomedicine.2022, 17:6513-6525.
  • ...
  • 生物活性
    Description: Standard reference
    In vivo:
    J Nat Prod. 2006 Dec;69(12):1687-91.
    Antihyperglycemic Activity and Chemical Constituents of Eysenhardtia platycarpa[Pubmed: 17190443 ]

    METHODS AND RESULTS:
    The methanolic extracts from branches (BEP) and leaves (LEP) of Eysenhardtia platycarpa significantly decreased the blood glucose levels in normal and streptozotocin (STZ)-induced diabetic rats. One new flavone, (1"R)-5,4',1"-trihydroxy-6,7-(3",3"-dimethylchroman)flavone (1), together with the known compounds 5,7-dihydroxy-6-methyl-8-prenylflavanone (3), 5,7-dihydroxy-8-methyl-6-prenylflavanone (4), 5,7-dihydroxy-6-prenylflavanone (5), 5,7-dihydroxy-8-prenylflavanone (6), 3-O-acetyloleanolic acid (7), oleanolic acid, 3beta-Acetoxy-11alpha,12alpha-epoxyoleanan-28,13beta-olide, lupeol, betulinic acid, beta-sitosterol, beta-sitosteryl beta-D-glucopyranoside, beta-sitosteryl palmitate, and 3-O-methyl-myo-inositol were isolated from BEP. Additionally, one new flavanone, (2S)-4'-O-methyl-6-methyl-8-prenylnaringenin (2), as well as the known compounds 3, 4, 6, 4'-O-methyl-8-prenylnaringenin (8), and 5-hydroxy-7-methoxy-8-prenylflavanone (9) were isolated from LEP.
    CONCLUSIONS:
    3-O-Acetyloleanolic acid (7), identified as the major constituent of BEP, showed a significant decrease (31 mg/kg of body weight, P < 0.05) in the glucose level of STZ-induced diabetic rats. The obtained results correlate with the traditional use of this species.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.9505 mL 9.7523 mL 19.5046 mL 39.0092 mL 48.7615 mL
    5 mM 0.3901 mL 1.9505 mL 3.9009 mL 7.8018 mL 9.7523 mL
    10 mM 0.195 mL 0.9752 mL 1.9505 mL 3.9009 mL 4.8761 mL
    50 mM 0.039 mL 0.195 mL 0.3901 mL 0.7802 mL 0.9752 mL
    100 mM 0.0195 mL 0.0975 mL 0.195 mL 0.3901 mL 0.4876 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    3beta-乙酰氧基-11alpha,12alpha-环氧齐墩果烷-13beta,28-内酯; 3beta-Acetoxy-11alpha,12alpha-epoxyoleanan-28,13beta-olide CFN96374 35738-25-1 C32H48O5 = 512.7 5mg QQ客服:3257982914
    16-脱氧柴胡甙元 F; 16-Deoxysaikogenin F CFN96265 57475-62-4 C30H48O3 = 456.7 5mg QQ客服:1457312923
    11alpha,12alpha-Epoxy-3beta,23-dihydroxy-30-norolean-20(29)-en-28,13beta-olide ; 11alpha,12alpha-Epoxy-3beta,23-dihydroxy-30-norolean-20(29)-en-28,13beta-olide CFN96095 186140-36-3 C29H42O5 = 470.7 5mg QQ客服:2159513211
    3-O-Acetyloleanderolide; 3-O-Acetyloleanderolide CFN97080 62498-83-3 C32H50O5 = 514.8 5mg QQ客服:3257982914
    Sculponeatic acid; Sculponeatic acid CFN99269 1169806-02-3 C30H46O4 = 470.7 5mg QQ客服:3257982914
    黄莲木酸; Moronic acid CFN97145 6713-27-5 C30H46O3 = 454.7 5mg QQ客服:215959384
    Pyrocincholic acid methyl ester; Pyrocincholic acid methyl ester CFN99079 107160-24-7 C30H48O3 = 456.7 5mg QQ客服:215959384
    苦杏酸; Camaric acid CFN99606 146450-83-1 C35H52O6 = 568.8 5mg QQ客服:215959384
    岩茨烯A; Rehmannic acid CFN97738 467-81-2 C35H52O5 = 552.80 5mg QQ客服:215959384
    Melliferone; Melliferone CFN95709 377724-68-0 C30H44O3 = 452.7 5mg QQ客服:215959384

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