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  • 麻风树碱3

    Jatrophane 3

    麻风树碱3
    产品编号 CFN98053
    CAS编号 210108-87-5
    分子式 = 分子量 C43H53NO14 = 807.9
    产品纯度 >=98%
    物理属性 Cryst.
    化合物类型 Diterpenoids
    植物来源 The branches of Jatropha carcas L.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    麻风树碱3 CFN98053 210108-87-5 1mg QQ客服:1457312923
    麻风树碱3 CFN98053 210108-87-5 5mg QQ客服:1457312923
    麻风树碱3 CFN98053 210108-87-5 10mg QQ客服:1457312923
    麻风树碱3 CFN98053 210108-87-5 20mg QQ客服:1457312923
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Pharmacognosy Journal2019, 11(2): 369-373
  • Toxicol Appl Pharmacol.2022, 434:115815.
  • BMC Complement Med Ther. 2020, 20(1):94.
  • Universitat Stuttgart2022, opus-12200.
  • Food Sci Biotechnol.2021, 30(2):217-226.
  • J Hematol Oncol.2018, 11(1):112
  • Front Cell Dev Biol.2020, 8:32.
  • J. of Med. Plant Research.2013, 90-151
  • ACS Synth Biol.2020, 9(9):2282-2290.
  • SBRAS2016, 12
  • Molecules2022, 27(14):4601
  • FASEB J.2019, 33(8):9685-9694
  • LWT-Food Science and Technology2017, 75:488-496
  • Metabolites.2020, 11(1):E11.
  • J Nat Prod.2022, doi: 10.1021
  • Molecules2022, 27(9):2827.
  • Processes 2021, 9(5),894.
  • Korean J. Medicinal Crop Sci.2018, 26(2):148-156
  • Planta Med.2019, 85(3):217-224
  • Cell Chem Biol.2019, 26(1):27-34
  • J Hepatocell Carcinoma.2022, 9:327-341.
  • European Journal of Integrative Medicine2018, 20:165-172
  • Applied Biological Chemistry2022, 65(12)
  • ...
  • 生物活性
    Description: (2R*,3R*,4S*,5R*,7S*,8S*,9S*,l3S*,14S*,15R*)-2,5,9,14-Tetraacetoxy-3-benzoyloxy-8,15-dihydroxy-7-isobutyroyloxyjatropha-6(17),11E-diene(Jatrophane 4 ) and (2R*,3R*, 4S*,5R*,7S*,8S*,9S*,l3S*,14S*,15R*)-2,5,14-triacetoxy-3-benzoyloxy-8,15-dihydroxy-7-isobutyroyloxy-9-nicotinoyloxyjatropha-6(17),11E-diene(Jatrophane 3) exhibit significant antifeedant activity against a generalist plant-feeding insect, the cotton bollworm (Helicoverpa armigera), with EC50 values of 0.36 and 0.43 ug/cm2, respectively.
    Targets: Antifection
    In vitro:
    Phytochemistry. 2017 Apr;136:56-64
    Chemical profile and defensive function of the latex of Euphorbia peplus.[Pubmed: 28062071 ]
    Plant latex is an endogenous fluid secreted from highly specialized laticifer cells and has been suggested to act as a plant defense system. The chemical profile of the latex of Euphorbia peplus was investigated.
    METHODS AND RESULTS:
    A total of 13 terpenoids including two previously unknown diterpenoids, (2S*,3S*,4R*,5R*,6R*,8R*,l1R*,13S*,14S*,15R*, 16R*)-5,8,15-triacetoxy-3-benzoyloxy-11,16-dihydroxy-9-oxopepluane and (2R*,3R*, 4S*,5R*,7S*,8S*,9S*,l3S*,14S*,15R*)-2,5,8,9,14-pentaacetoxy-3-benzoyloxy-15-hydroxy-7-isobutyroyloxyjatropha-6(17),11E-diene), ten known diterpenoids, and a known acyclic triterpene alcohol peplusol, were identified, using HPLC and UPLC-MS/MS analyses and through comparison with the authentic compounds isolated from the whole plant. The diterpenoids exhibited significant antifeedant activity against a generalist plant-feeding insect, the cotton bollworm (Helicoverpa armigera), with EC50 values ranging from 0.36 to 4.60 μg/cm2. In particular, (2R*,3R*,4S*,5R*,7S*,8S*,9S*,l3S*,14S*,15R*)-2,5,9,14-tetraacetoxy-3-benzoyloxy-8,15-dihydroxy-7-isobutyroyloxyjatropha-6(17),11E-diene (Jatrophane 4)and (2R*,3R*, 4S*,5R*,7S*,8S*,9S*,l3S*,14S*,15R*)-2,5,14-triacetoxy-3-benzoyloxy-8,15-dihydroxy-7-isobutyroyloxy-9-nicotinoyloxyjatropha-6(17),11E-diene(Jatrophane 3) had EC50 values of 0.36 and 0.43 μg/cm2, respectively, which were approximately 7-fold more potent than commercial neem oil (EC50 = 2.62 μg/cm2). In addition, the major peplusol showed obvious antifungal activity against three strains of agricultural phytopathogenic fungi, Rhizoctonia solani, Colletotrichum litchi and Fusarium oxysporum f. sp. niveum.
    CONCLUSIONS:
    The results indicated that terpenoids in the latex of E. peplus are rich and highly diversified, and might function as constitutive defense metabolites against insect herbivores and pathogens for the plant.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.2378 mL 6.1889 mL 12.3778 mL 24.7555 mL 30.9444 mL
    5 mM 0.2476 mL 1.2378 mL 2.4756 mL 4.9511 mL 6.1889 mL
    10 mM 0.1238 mL 0.6189 mL 1.2378 mL 2.4756 mL 3.0944 mL
    50 mM 0.0248 mL 0.1238 mL 0.2476 mL 0.4951 mL 0.6189 mL
    100 mM 0.0124 mL 0.0619 mL 0.1238 mL 0.2476 mL 0.3094 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    甘遂萜酯E; Kansuinine E CFN92869 672945-84-5 C41H47NO14 = 777.8 5mg QQ客服:215959384
    Jatrophane I; Jatrophane I CFN89380 210108-85-3 C36H45NO13 = 699.74 5mg QQ客服:215959384
    Jatrophane VI ; Jatrophane VI CFN89381 210108-90-0 C37H48O14 = 716.76 5mg QQ客服:2159513211
    麻风树碱4; Jatrophane 4 CFN98054 210108-88-6 C39H52O14 = 744.8 5mg QQ客服:1457312923
    麻风树碱2; Jatrophane 2 CFN98052 210108-86-4 C39H50O15 = 758.8 5mg QQ客服:1413575084
    麻风树碱5; Jatrophane 5 CFN98055 210108-89-7 C41H49NO14 = 779.8 5mg QQ客服:2056216494
    麻风树碱3; Jatrophane 3 CFN98053 210108-87-5 C43H53NO14 = 807.9 5mg QQ客服:1413575084
    Pepluanin A; Pepluanin A CFN97144 670257-89-3 C43H51NO15 = 821.9 5mg QQ客服:1413575084
    甘遂萜酯A; Kansuinine A CFN92863 57701-86-7 C37H46O15 = 730.8 5mg QQ客服:3257982914
    甘遂萜酯B; Kansuinine B CFN92866 57685-46-8 C38H42O14 = 722.7 5mg QQ客服:1413575084

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