1-脱氢-6-姜酮

1-Dehydro-6-gingerdione

	产品编号	CFN92298
	CAS编号	76060-35-0
	分子式 = 分子量	C₁₇H₂₂O₄ = 290.4
	产品纯度	>=98%
	物理属性	Powder
	化合物类型	Phenols
	植物来源	The rhizomes of Zingber officinale Rosc.
ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用

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产品名称	产品编号	CAS编号	包装	QQ客服
1-脱氢-6-姜酮	CFN92298	76060-35-0	1mg	QQ客服：1457312923
1-脱氢-6-姜酮	CFN92298	76060-35-0	5mg	QQ客服：1457312923
1-脱氢-6-姜酮	CFN92298	76060-35-0	10mg	QQ客服：1457312923
1-脱氢-6-姜酮	CFN92298	76060-35-0	20mg	QQ客服：1457312923

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ChemFaces的产品在许多优秀和顶级科学期刊中被引用

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089

Monash University Malaysia (Malaysia)

Leibniz-Institut für Pflanzenbiochemie (IPB) (Germany)

University of Melbourne (Australia)

Mahidol University (Thailand)

University of Zurich (Switzerland)

Macau University of Science and Technology (China)

Kyung Hee University (Korea)

Cancer Research Initatives Foundation(CARIF) (Malaysia)

University of Pretoria (South Africa)

Centralised Purchases Unit (CPU), B.I.T.S (India)

Shanghai Institute of Organic Chemistry (China)

Universidade Federal de Pernambuco (UFPE) (Brazil)

Universitas Airlangga (Indonesia)

Donald Danforth Plant Science Center (USA)

More...

Description:

1-Dehydro-6-gingerdione is a 5-HT1A receptor partial agonist.1-Dehydro-6-gingerdione has antioxidant and anti-inflammatory activities, it significantly suppresses the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) proteins in a concentration-dependent fashion.

Targets:

PGE | NOS | COX

In vitro:

Food Chem. 2012 Nov 15;135(2):332-7.

In vitro antioxidant and anti-inflammatory activities of 1-dehydro-[6]-gingerdione, 6-shogaol, 6-dehydroshogaol and hexahydrocurcumin.[Pubmed: 22868095]

Hexahydrocurcumin, 1-Dehydro-6-gingerdione, 6-dehydroshogaol and 6-shogaol were evaluated for their antioxidant and anti-inflammatory activities in the present study.
METHODS AND RESULTS:
The relative antioxidant potencies of ginger compounds decreased in similar order of 1-Dehydro-6-gingerdione, hexahydrocurcumin>6-shogaol>6-dehydroshogaol in both 1,1-diphenyl-2-picyrlhydrazyl (DPPH) radical-scavenging and trolox equivalent antioxidant capacity (TEAC) assays. All tested compounds could attenuate lipopolysaccharide (LPS)-elicited increase of prostaglandin E2 (PGE(2)) in murine macrophages (RAW 264.7) in a concentration-dependent manner but hexahydrocurcumin of 7μM and 6-shogaol of 7μM. The strongest inhibitory effect was observed for 6-dehydroshogaol and 6-shogaol at 14μM with the inhibition of 53.3% and 48.9%, respectively. Furthermore, both 6-dehydroshogaol and 1-Dehydro-6-gingerdione significantly suppressed the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) proteins in a concentration-dependent fashion.
CONCLUSIONS:
These results contribute to our theoretical understanding of the potential beneficial effects of consuming ginger as a food and/or dietary supplement.

产品名称	产品编号	CAS编号	分子式 = 分子量	位单	联系QQ
6-姜酚; 6-Gingerol	CFN99931	23513-14-6	C₁₇H₂₆O₄ = 294.4	20mg	QQ客服：1457312923
甲基-6-姜辣素; Methyl-6-gingerol	CFN95833	23513-10-2	C₁₈H₂₈O₄ = 308.4	20mg	QQ客服：3257982914
8-姜酚; 8-Gingerol	CFN99131	23513-08-8	C₁₉H₃₀O₄ = 322.44	20mg	QQ客服：215959384
5-甲基-8-姜辣素; 5-Methoxy-[8]-gingerol	CFN95945	863780-81-8	C₂₀H₃₂O₄ = 336.5	10mg	QQ客服：215959384
10-姜酚; 10-Gingerol	CFN99132	23513-15-7	C₂₁H₃₄O₄ = 350.49	20mg	QQ客服：2056216494
1-脱氢-10-姜酮; 1-Dehydro-10-gingerdione	CFN92374	136826-50-1	C₂₁H₃₀O₄ = 346.5	5mg	QQ客服：215959384
二乙酰氧基-4-姜二醇; Diacetoxy-4-gingerdiol	CFN92373	863780-88-5	C₁₉H₂₈O₆ = 352.4	5mg	QQ客服：1457312923
甲基二乙酰氧基-6-姜二醇; Methyl diacetoxy-6-gingerdiol	CFN92301	863780-90-9	C₂₂H₃₄O₆ = 394.5	5mg	QQ客服：2159513211
1-脱氢-6-姜酮; 1-Dehydro-6-gingerdione	CFN92298	76060-35-0	C₁₇H₂₂O₄ = 290.4	10mg	QQ客服：1457312923
6-姜烯酚; 6-Shogaol	CFN99531	555-66-8	C₁₇H₂₄O₃ = 276.37	20mg	QQ客服：1457312923

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	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.4435 mL	17.2176 mL	34.4353 mL	68.8705 mL	86.0882 mL
5 mM	0.6887 mL	3.4435 mL	6.8871 mL	13.7741 mL	17.2176 mL
10 mM	0.3444 mL	1.7218 mL	3.4435 mL	6.8871 mL	8.6088 mL
50 mM	0.0689 mL	0.3444 mL	0.6887 mL	1.3774 mL	1.7218 mL
100 mM	0.0344 mL	0.1722 mL	0.3444 mL	0.6887 mL	0.8609 mL