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  • 豆甾-4,22-二烯-3-酮

    Stigmasta-4,22-dien-3-one

    豆甾-4,22-二烯-3-酮
    产品编号 CFN98934
    CAS编号 55722-32-2
    分子式 = 分子量 C29H46O = 410.7
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Steroids
    植物来源 The flowers of Magnolia biondii
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    豆甾-4,22-二烯-3-酮 CFN98934 55722-32-2 1mg QQ客服:2932563308
    豆甾-4,22-二烯-3-酮 CFN98934 55722-32-2 5mg QQ客服:2932563308
    豆甾-4,22-二烯-3-酮 CFN98934 55722-32-2 10mg QQ客服:2932563308
    豆甾-4,22-二烯-3-酮 CFN98934 55722-32-2 20mg QQ客服:2932563308
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Korea Intitute of Science and Technology (KIST) (Korea)
  • University of the Basque Country (Spain)
  • Korea Food Research Institute(KFRI) (Korea)
  • University of Auckland (New Zealand)
  • Srinakharinwirot University (Thailand)
  • Universidade Federal de Pernambuco (UFPE) (Brazil)
  • The Vancouver Prostate Centre (VPC) (Canada)
  • Helmholtz Zentrum München (Germany)
  • Institute of Bioorganic Chemistry Polish Academy of Sciences (Poland)
  • Uniwersytet Medyczny w ?odzi (Poland)
  • University of Indonesia (Indonesia)
  • Semmelweis Unicersity (Hungary)
  • Fraunhofer-Institut für Molekularbiologie und Angewandte ?kologie IME (Germany)
  • Leibniz Institute of Plant Biochemistry (Germany)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • J. of Med. Plant Research.2013, 90-151
  • J Pharm Biomed Anal.2016, 129:50-59
  • Oncotarget.2016, 8(51):88386-88400
  • Mol Pharm.2017, 14(9):3164-3177
  • Evid Based Complement Alternat Med.2017, 2017:7383104
  • Cell Physiol Biochem.2017, 44(4):1381-1395
  • Oncotarget.2017, 8(53):90925-90947
  • J Chromatogr B Analyt Technol Biomed Life Sci.2018, 1080:27-36
  • Yakugaku Zasshi.2018, 138(4):571-579
  • Br J Pharmacol.2018, 175(6):902-923
  • Phytother Res.2018, 32(12):2551-2559
  • Biol Pharm Bull.2018, 41(1):65-72
  • Biol Pharm Bull.2018, 41(11):1685-1693
  • Biochemistry.2018, 57(40):5886-5896
  • Front Pharmacol.2018, 9:756
  • Front Aging Neurosci.2019, 11:230
  • Int J Mol Sci.2019, 20(21):E5488
  • Molecules.2019, 24(23):E4303
  • Cell Chem Biol.2019, 26(1):27-34
  • J of Dentistry & Oral Health2019, 2641-1962
  • The Malaysian journal of pathology2019, 41(3):243-251
  • Phytomedicine.2019, 58:152893
  • Saudi Pharm J2020, 10.1016
  • ...
  • 生物活性
    Description: Stigmasta-4,22-dien-3-one has antioxidant activity.
    In vitro:
    Molecules. 2014 Nov 3;19(11):17829-38.
    Antioxidant and anticancer aporphine alkaloids from the leaves of Nelumbo nucifera Gaertn. cv. Rosa-plena.[Pubmed: 25372397]

    METHODS AND RESULTS:
    Fifteen compounds were extracted and purified from the leaves of Nelumbo nucifera Gaertn. cv. Rosa-plena. These compounds include liriodenine (1), lysicamine (2), (-)-anonaine (3), (-)-asimilobine (4), (-)-caaverine (5), (-)-N-methylasimilobine (6), (-)-nuciferine (7), (-)-nornuciferine (8), (-)-roemerine (9), 7-hydroxydehydronuciferine (10) cepharadione B (11), β-sitostenone (12), stigmasta-4,22-dien-3-one (13) and two chlorophylls: pheophytin-a (14) and aristophyll-C (15). The anti-oxidation activity of the compounds was examined by antiradical scavenging, metal chelating and ferric reducing power assays. The results have shown that these compounds have antioxidative activity. The study has also examined the antiproliferation activity of the isolated compounds against human melanoma, prostate and gastric cancer cells. The results shown that 7-hydroxydehydronuciferine (10) significantly inhibited the proliferation of melanoma, prostate and gastric cancer cells.
    CONCLUSIONS:
    Together, these findings suggest that leaves of Nelumbo nucifera Gaertn. cv. Rosa-plena are a good resource for obtaining the biologically active substances with antioxidant properties.
    Planta Med. 2000 Apr;66(3):251-6.
    Anti-platelet aggregation alkaloids and lignans from Hernandia nymphaeifolia.[Pubmed: 10821052 ]

    METHODS AND RESULTS:
    A new aporphine, N-(N-methylcarbamoyl)-O-methyl-bulbocapnine (1), together with seven known compounds, (-)-5'-methoxypodorhizol (2), a mixture of beta-sitosterone (3) and Stigmasta-4,22-dien-3-one (4), a mixture of 3 beta-hydroxystigmast-5-en-7-one (5) and 3 beta-hydroxystigmasta-5,22-dien-7-one (6), and a mixture of 6 alpha-hydroxystigmast-4-en-3-one (7) and 6 alpha-hydroxyStigmasta-4,22-dien-3-one (8), were isolated in continuing studies on the trunk bark of Formosan Hernandia nymphaeifolia.
    CONCLUSIONS:
    The structures of these compounds were determined through spectral analyses. In addition, the previously reported six alkaloids, laurotetanine, oxohernagine, thalicarpine, reticuline, (+)-vateamine-2'-beta-N-oxide, (+)-hernandaline and six lignans, (+)-epiaschantin, (+)-epimagnolin, (+)-epiyangambin, (-)-hernone, (-)-yatein, (-)-deoxypodophyllotoxin were demonstrated to have anti-platelet aggregation activity.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.4349 mL 12.1743 mL 24.3487 mL 48.6973 mL 60.8717 mL
    5 mM 0.487 mL 2.4349 mL 4.8697 mL 9.7395 mL 12.1743 mL
    10 mM 0.2435 mL 1.2174 mL 2.4349 mL 4.8697 mL 6.0872 mL
    50 mM 0.0487 mL 0.2435 mL 0.487 mL 0.9739 mL 1.2174 mL
    100 mM 0.0243 mL 0.1217 mL 0.2435 mL 0.487 mL 0.6087 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    β-谷甾醇; Beta-Sitosterol CFN99916 83-46-5 C29H50O = 414.69 20mg QQ客服:3257982914
    β-谷甾基十六烷酸酯,棕榈酸谷甾醇酯; Sitosteryl palmitate CFN98235 2308-85-2 C45H80O2 = 653.1 5mg QQ客服:2932563308
    豆甾-5,8-二烯-3-醇; Stigmasta-5,8-dien-3-ol CFN98959 570-72-9 C29H48O = 412.7 5mg QQ客服:3257982914
    alpha-菠菜甾醇; alpha-Spinasterol CFN98748 481-18-5 C29H48O = 412.7 10 mg QQ客服:1148253675
    alpha-菠菜甾醇乙酸酯; alpha-Spinasterol acetate CFN98692 4651-46-1 C31H50O2 = 454.7 5mg QQ客服:3257982914
    alpha-波菜甾酮; alpha-Spinasterone CFN98243 23455-44-9 C29H46O = 410.7 5mg QQ客服:2159513211
    豆甾-4-烯-3-酮; Sitostenone CFN99073 1058-61-3 C29H48O = 412.7 5mg QQ客服:2159513211
    豆甾-4,22,25-三烯-3-酮; Stigmasta-4,22,25-trien-3-one CFN97408 848669-09-0 C29H44O = 408.7 5mg QQ客服:1413575084
    豆甾-4,22-二烯-3-酮; Stigmasta-4,22-dien-3-one CFN98934 55722-32-2 C29H46O = 410.7 5mg QQ客服:3257982914
    豆甾醇; Stigmasterol CFN97326 83-48-7 C29H48O = 412.7 20mg QQ客服:2932563308

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