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  • 豆甾-4-烯-3-酮

    Sitostenone

    豆甾-4-烯-3-酮
    产品编号 CFN99073
    CAS编号 1058-61-3
    分子式 = 分子量 C29H48O = 412.7
    产品纯度 >=98%
    物理属性 Cryst.
    化合物类型 Steroids
    植物来源 The roots of Xanthium sibiricum
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    豆甾-4-烯-3-酮 CFN99073 1058-61-3 1mg QQ客服:3257982914
    豆甾-4-烯-3-酮 CFN99073 1058-61-3 5mg QQ客服:3257982914
    豆甾-4-烯-3-酮 CFN99073 1058-61-3 10mg QQ客服:3257982914
    豆甾-4-烯-3-酮 CFN99073 1058-61-3 20mg QQ客服:3257982914
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Wroclaw Medical University (Poland)
  • Deutsches Krebsforschungszentrum (Germany)
  • Institute of Tropical Disease Universitas Airlangga (Indonesia)
  • VIT University (India)
  • Universidad de La Salle (Mexico)
  • S.N.D.T. Women's University (India)
  • Florida International University (USA)
  • Institute of Bioorganic Chemistry Polish Academy of Sciences (Poland)
  • Seoul National University (Korea)
  • Worcester Polytechnic Institute (USA)
  • Tokyo Woman's Christian University (Japan)
  • Universitas Airlangga (Indonesia)
  • Northeast Normal University Changchun (China)
  • Weizmann Institute of Science (Israel)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Int J Mol Sci.2015, 16(8):18396-411
  • J-STAGE2015, 249-255
  • China Pharmacy2015, 26(27)
  • Oncotarget.2015, 6(31):30831-49
  • Br J Pharmacol.2016, 173(2):396-410
  • Analytical sci. & Tech2016, 186-193
  • Nat Prod Sci.2016, 22(2)
  • J of the Korean Society of Food Science and Nutrition2016, 45(7):1017-1025
  • BMC Complement Altern Med.2017, 17(1):384
  • J Ethnopharmacol.2017, 198:91-97
  • Molecules.2017, 22(11)
  • Front Immunol.2017, 8:1542
  • J Cell Mol Med.2018, 22(9):4236-4242
  • Molecules.2018, 23(7):E1817
  • Asian Journal of Chemistry2018, 30(12):2699-2703
  • The Journal of Agromedicine and Medical Sciences2018, 4(1)
  • J Liq Chromatogr R T2018, 41(12):761-769
  • Arch Biochem Biophys.2018, 644:93-99
  • Food Chem.2019, 278:683-691
  • J Funct Foods2019, 54:449-456
  • Genes Genomics.2020, 10.1007
  • Plos One.2020, 10.1371
  • Antioxidants (Basel).2020, 9(2):E120
  • ...
  • 生物活性
    Description: β-Sitostenone has antioxidation activity. Stigmasta-4-en-3-one(Sitostenone) can be used for the treatment of androgen-dependent diseases, especially for the treatment of benign prostatic hyperplasia.
    In vitro:
    Molecules. 2014 Nov 3;19(11):17829-38
    Antioxidant and anticancer aporphine alkaloids from the leaves of Nelumbo nucifera Gaertn. cv. Rosa-plena.[Pubmed: 25372397 ]
    Fifteen compounds were extracted and purified from the leaves of Nelumbo nucifera Gaertn. cv. Rosa-plena.
    METHODS AND RESULTS:
    These compounds include liriodenine (1), lysicamine (2), (-)-anonaine (3), (-)-asimilobine (4), (-)-caaverine (5), (-)-N-methylasimilobine (6), (-)-nuciferine (7), (-)-nornuciferine (8), (-)-roemerine (9), 7-hydroxydehydronuciferine (10) cepharadione B (11), β-Sitostenone (12), stigmasta-4,22-dien-3-one (13) and two chlorophylls: pheophytin-a (14) and aristophyll-C (15). The anti-oxidation activity of the compounds was examined by antiradical scavenging, metal chelating and ferric reducing power assays. The results have shown that these compounds have antioxidative activity. The study has also examined the antiproliferation activity of the isolated compounds against human melanoma, prostate and gastric cancer cells. The results shown that 7-hydroxydehydronuciferine (10) significantly inhibited the proliferation of melanoma, prostate and gastric cancer cells.
    CONCLUSIONS:
    Together, these findings suggest that leaves of Nelumbo nucifera Gaertn. cv. Rosa-plena are a good resource for obtaining the biologically active substances with antioxidant properties.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.4231 mL 12.1153 mL 24.2307 mL 48.4614 mL 60.5767 mL
    5 mM 0.4846 mL 2.4231 mL 4.8461 mL 9.6923 mL 12.1153 mL
    10 mM 0.2423 mL 1.2115 mL 2.4231 mL 4.8461 mL 6.0577 mL
    50 mM 0.0485 mL 0.2423 mL 0.4846 mL 0.9692 mL 1.2115 mL
    100 mM 0.0242 mL 0.1212 mL 0.2423 mL 0.4846 mL 0.6058 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    豆甾-4-烯-3-酮; Sitostenone CFN99073 1058-61-3 C29H48O = 412.7 5mg QQ客服:2159513211
    豆甾-4,22,25-三烯-3-酮; Stigmasta-4,22,25-trien-3-one CFN97408 848669-09-0 C29H44O = 408.7 5mg QQ客服:2159513211
    豆甾-4,22-二烯-3-酮; Stigmasta-4,22-dien-3-one CFN98934 55722-32-2 C29H46O = 410.7 5mg QQ客服:215959384
    豆甾醇; Stigmasterol CFN97326 83-48-7 C29H48O = 412.7 20mg QQ客服:3257982914
    β-谷甾醇; Beta-Sitosterol CFN99916 83-46-5 C29H50O = 414.69 20mg QQ客服:1148253675
    β-谷甾基十六烷酸酯,棕榈酸谷甾醇酯; Sitosteryl palmitate CFN98235 2308-85-2 C45H80O2 = 653.1 5mg QQ客服:1413575084
    豆甾-5,8-二烯-3-醇; Stigmasta-5,8-dien-3-ol CFN98959 570-72-9 C29H48O = 412.7 5mg QQ客服:215959384
    alpha-菠菜甾醇; alpha-Spinasterol CFN98748 481-18-5 C29H48O = 412.7 10 mg QQ客服:3257982914
    alpha-菠菜甾醇乙酸酯; alpha-Spinasterol acetate CFN98692 4651-46-1 C31H50O2 = 454.7 5mg QQ客服:1413575084
    alpha-波菜甾酮; alpha-Spinasterone CFN98243 23455-44-9 C29H46O = 410.7 5mg QQ客服:2159513211

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