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    2''-O-鼠李糖基淫羊藿次苷II

    2''-O-Rhamnosylicariside II

    2''-O-鼠李糖基淫羊藿次苷II
    产品编号 CFN92551
    CAS编号 135293-13-9
    分子式 = 分子量 C33H40O14 = 660.7
    产品纯度 >=98%
    物理属性 Yellow powder
    化合物类型 Flavonoids
    植物来源 The herbs of Epimedium brevicornu
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    2''-O-鼠李糖基淫羊藿次苷II CFN92551 135293-13-9 1mg QQ客服:1413575084
    2''-O-鼠李糖基淫羊藿次苷II CFN92551 135293-13-9 5mg QQ客服:1413575084
    2''-O-鼠李糖基淫羊藿次苷II CFN92551 135293-13-9 10mg QQ客服:1413575084
    2''-O-鼠李糖基淫羊藿次苷II CFN92551 135293-13-9 20mg QQ客服:1413575084
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    Cell. 2018 Jan 11;172(1-2):249-261.e12.
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    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
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    Nature Plants. 2016 Dec 22;3: 16206.
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  • ...
  • 生物活性
    Description: 2″-O-Rhamnosylicariside II shows potent antioxidant activity, with IC50 values of 11.5 ug/mL and 90.5 uM. It shows potent inhibitory activities on osteoclast-like cell formation at a concentration of 2 uM without toxic effects.
    In vitro:
    Journal of Traditional Medicines, 2007, 24:19-23.
    Inhibitory effect of constituents of Bu-Shen-Jian-Gu-Tang on osteoclast-like cell formation[Reference: WebLink]
    The constituents of Bu-Shen-Jian-Gu-Tang and their inhibitory activities on osteoclast-Iike cell formation were investigated. Bu-Shen-Jian-Gu-Tang was fractionated by a Diaion HP-20 column with EtOH-H_2O, and the 60% and 90% EtOH-H_20 fractions showed more potent inhibitory activities on osteoclast-like cell formation and bone resorption.
    METHODS AND RESULTS:
    Chemical investigation of these two fractions resulted in the isolation of 11 compounds, for which the structures were elucidated based on spectroscopic analysis and chemical reactions. The inhibitory activities of the isolated compounds on osteoclast-like cell formation were evaluated. Among the eleven compounds, icariin (1), icarisid II (2), 2''-O-Rhamnosylicariside II (3), kaempferol (8), chikusetsusaponin IVa (10) and chikusetsusaponin V (11) showed potent inhibitory activities at a concentration of 2 μM without toxic effects.
    CONCLUSIONS:
    The preventive effect of Bu-Shen-Jian-Gu-Tang on bone loss may be due to the inhibitory activities of these compounds.
    Natural Product Sciences, 2008, 14(4):233-8.
    Flavonol Glycosides with Antioxidant Activity from the Aerial Parts of Epimedium koreanum Nakai[Reference: WebLink]
    The aerial parts of Epimedium koreanum Nakai have been used to stimulate hormone secretion in treating impotence.
    METHODS AND RESULTS:
    Ten flavonol glycosides, 3,4,5-trihydroxy-8-prenylflavone 7-O-[β-D-glucopyranosyl(1 → 2)-β-D-glucopyranoside] (1), hyperoside (2), icarisid II (3), 2''-O-Rhamnosylicariside II (4), epimedin A (5), epimedin B (6), epimedin C (7), icariin (8), hexandraside E (9), and epimedoside A (10) were isolated from the an ethylacetate soluble extracts of the aerial parts of Epimedium koreanum Nakai through activity-monitord fractionation and isolation method. The structures of compounds 1 - 10 were elucidated by high resolution fast atom bombardment mass spectrometry and two dimentional nuclear magnetic resonance spectroscopy analysis.
    CONCLUSIONS:
    Compounds 1 and 4 showed potent antioxidant activity, with IC50 values of 19.7 and 11.5 μg/mL and 88.2 and 90.5 μM, respectively.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.5135 mL 7.5677 mL 15.1355 mL 30.2709 mL 37.8387 mL
    5 mM 0.3027 mL 1.5135 mL 3.0271 mL 6.0542 mL 7.5677 mL
    10 mM 0.1514 mL 0.7568 mL 1.5135 mL 3.0271 mL 3.7839 mL
    50 mM 0.0303 mL 0.1514 mL 0.3027 mL 0.6054 mL 0.7568 mL
    100 mM 0.0151 mL 0.0757 mL 0.1514 mL 0.3027 mL 0.3784 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    箭藿苷B; Sagittatoside B CFN90211 118525-36-3 C32H38O14 = 646.64 5mg QQ客服:2056216494
    2''-O-鼠李糖基淫羊藿次苷II; 2''-O-Rhamnosylicariside II CFN92551 135293-13-9 C33H40O14 = 660.7 10mg QQ客服:2932563308
    Sutchuenmedin A; Sutchuenmedin A CFN96542 1197194-31-2 C33H38O14 = 658.65 5mg QQ客服:2056216494
    箭藿苷A; Sagittatoside A CFN90139 118525-35-2 C33H40O15 = 676.67 5mg QQ客服:2932563308
    箭藿苷C; Sagittatoside C CFN92077 118525-37-4 C35H42O16 = 718.7 5mg QQ客服:2056216494
    异箭藿苷A; Iso-sagittatoside A CFN91155 503456-08-4 C33H40O15 = 676.7 5mg QQ客服:2159513211
    朝鲜淫羊藿苷A;朝藿苷甲; Korepimedoside A CFN92905 106441-31-0 C37H44O17 = 760.74 5mg QQ客服:1413575084
    宝藿苷VII; Baohuoside VII CFN90765 119730-89-1 C33H40O15 = 676.7 10mg QQ客服:2932563308
    淫羊藿苷; Icariin CFN99554 489-32-7 C33H40O15 = 676.65 20mg QQ客服:2932563308
    朝藿定B; Epimedin B CFN99940 110623-73-9 C38H48O19 = 808.78 20mg QQ客服:2056216494

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