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  • 紫黄檀素

    Violanone

    紫黄檀素
    产品编号 CFN95385
    CAS编号 52250-38-1
    分子式 = 分子量 C17H16O6 = 316.3
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Flavonoids
    植物来源 The roots of Parochetus communis
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    紫黄檀素 CFN95385 52250-38-1 1mg QQ客服:1413575084
    紫黄檀素 CFN95385 52250-38-1 5mg QQ客服:1413575084
    紫黄檀素 CFN95385 52250-38-1 10mg QQ客服:1413575084
    紫黄檀素 CFN95385 52250-38-1 20mg QQ客服:1413575084
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Nicolaus Copernicus Uniwersity (Poland)
  • National Cancer Center Research Institute (Japan)
  • University of British Columbia (Canada)
  • Cancer Research Initatives Foundation(CARIF) (Malaysia)
  • Osmania University (India)
  • Heinrich-Heine-University Düsseldorf (Germany)
  • Universite Libre de Bruxelles (Belgium)
  • University of Parma (Italy)
  • Periyar University (India)
  • University of Wollongong (Australia)
  • China Medical University (Taiwan)
  • FORTH-IMBB (Greece)
  • Chulalongkorn University (Thailand)
  • VIB Department of Plant Systems Biology, UGent (PSB) (Belgium)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Academic J of Second Military Medical University2019, 40(1)
  • Front Immunol. 2020, 11:62.
  • Phytother Res.2022, 35844057.
  • Anal Chim Acta.2018, 1039:162-171
  • Preprints2021, doi:10.20944
  • J Nat Med.2022, 76(1):59-67.
  • Antioxidants (Basel).2023, 12(12):2078.
  • J Med Chem.2023, 66(6):4106-4130.
  • Nutrients.2023, 15(12):2810.
  • Phytomedicine2022, 104:154337.
  • Sustainability2021, 13(23),12981.
  • Int J Mol Sci.2018, 19(2)
  • Acta Physiologiae Plantarum2016, 38:7
  • New Zealand J. Forestry Sci.2014, 44:17
  • Life Sci.2023, 332:122107.
  • TCI CO.2019, US20190151281A1
  • Theoretical and Experimental Plant Physiology 2022, 34,53-62
  • Molecules.2023, 28(7):3039.
  • J Nat Prod.2018, 81(4):966-975
  • Pharmacogn Mag.2015, 11(43):562-6
  • Chin Med.2022, 17(1):66.
  • Antioxidants (Basel).2021, 10(10):1638.
  • Toxicol In Vitro.2023, 93:105667.
  • ...
  • 生物活性
    Description: Violanone, an isoflavanone compound, can inhibit tubulin polymerization. Violanone also exhibits larvicidal activity against A. aegypti.
    In vitro:
    Exp Parasitol . 2015 Jun;153:160-164.
    Extract of Bowdichia virgilioides and maackiain as larvicidal agent against Aedes aegypti mosquito[Pubmed: 25819294]
    The larvicidal activities of extracts of three hardwood species (Hymenaea stigonorcapa, Anadenanthera colubrina and Bowdichia virgilioides) against 4th instar larvae of Aedes aegypti were evaluated using WHO guidelines. Extracts of H. stignocarpa and A. colubrina showed weak activity. The highest larvicidal effect was obtained with the cyclohexane extract of the heartwood of B. virgilioides, which caused 100% mortality at concentrations at 50 and 100 μg/mL. Fraction toluene/EtOAc (8:2) from this extract showed larvicidal activity (LC₅₀ = 34.90 ± 1.27 μg/mL). A mixture of two compounds identified as medicarpin and maackiain exhibited a very good larvicidal activity (sub-fraction 2, LC₅₀ = 17.5 ± 1.87 μg/mL) and maackiain showed to be a strong larvicidal compound (LC₅₀ = 21.95 ± 1.34 μg/mL). This result can be of value in the search for new natural larvicidal compounds from other hardwood plant extracts and presents the first report of B. virgilioides being used to control a mosquito vector.
    Tetrahedron. 2007 Dec 24; 63(52): 12986-12993.
    Synthesis and biological evaluation of isoflavone analogues from Dalbergia oliveri[Reference: WebLink]
    Mucronulatol 1 and violanone 2 isolated from Dalbergia oliveri Gamble, and the corresponding isoflavone 3 were prepared by ligand coupling reactions involving organolead reagent. Biological studies have shown a significant cytotoxic effect against an HBL100 leukemia cell line only for isoflavan 1 with an IC50 value amounting to 5.7 μM. All the drugs modestly inhibit the in vitro microtubule assembly, independently of the cytotoxic ability. Natural compounds 1 and 2 have no antibacterial activity, but are potent inhibitors of the Fusarium oxysporum phytopathogenic fungal growth.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.1616 mL 15.8078 mL 31.6156 mL 63.2311 mL 79.0389 mL
    5 mM 0.6323 mL 3.1616 mL 6.3231 mL 12.6462 mL 15.8078 mL
    10 mM 0.3162 mL 1.5808 mL 3.1616 mL 6.3231 mL 7.9039 mL
    50 mM 0.0632 mL 0.3162 mL 0.6323 mL 1.2646 mL 1.5808 mL
    100 mM 0.0316 mL 0.1581 mL 0.3162 mL 0.6323 mL 0.7904 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    5-O-Methylgenistein; 5-O-Methylgenistein CFN89437 4569-98-6 C16H12O5 = 284.26 5mg QQ客服:215959384
    鹰嘴豆芽素A; Biochanin A CFN99734 491-80-5 C16H12O5 = 284.26 20mg QQ客服:2159513211
    4’7-二甲氧基-5-羟基异黄酮; 7-O-Methylbiochanin A CFN91010 34086-51-6 C17H14O5 = 298.3 10mg QQ客服:215959384
    樱黄素; Prunetin CFN90189 552-59-0 C16H12O5 = 284.26 20mg QQ客服:2159513211
    6-Methylgenistein; 6-Methylgenistein CFN96540 97575-49-0 C16H12O5 = 284.26 5mg QQ客服:215959384
    Cristatein; Cristatein CFN95647 919490-61-2 C18H16O6 = 328.3 10mg QQ客服:2056216494
    6,7,4'-三羟基异黄酮; 6,7,4'-Trihydroxyisoflavone CFN90796 17817-31-1 C15H10O5 = 270.2 5mg QQ客服:215959384
    黄豆黄素; Glycitein CFN99106 40957-83-3 C16H12O5 = 284.26 20mg QQ客服:2056216494
    Afrormosine; Afrormosine CFN92347 550-79-8 C17H14O5 = 298.3 5mg QQ客服:3257982914
    鸢尾黄素; Tectorigenin CFN99920 548-77-6 C16H12O6 = 300.26 20mg QQ客服:1413575084

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