氧化石蒜碱
Ungeremine
|
|
产品编号 |
CFN93030 |
| CAS编号 |
72510-04-4 |
| 分子式 = 分子量 |
C16H12NO3+ = 266.27 |
| 产品纯度 |
>=98% |
| 物理属性 |
Powder |
| 化合物类型 |
Alkaloids |
| 植物来源 |
The bulbus of Lycoris radiata (L. Herit.) Herb |
| ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用 |
|
| 产品名称 |
产品编号 |
CAS编号 |
包装 |
QQ客服 |
| 氧化石蒜碱 |
CFN93030 |
72510-04-4 |
10mg |
QQ客服：3004468088 |
| 氧化石蒜碱 |
CFN93030 |
72510-04-4 |
20mg |
QQ客服：3004468088 |
| 氧化石蒜碱 |
CFN93030 |
72510-04-4 |
50mg |
QQ客服：3004468088 |
| 氧化石蒜碱 |
CFN93030 |
72510-04-4 |
100mg |
QQ客服：3004468088 |
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ChemFaces的产品在许多优秀和顶级科学期刊中被引用
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
我们的产品现已经出口到下面的研究机构与大学，并且还在增涨
VIB Department of Plant Systems Biology, UGent (PSB) (Belgium)
University of Mysore (India)
Indian Institute of Science (India)
Sant Gadge Baba Amravati University (India)
Leibniz Institute of Plant Biochemistry (Germany)
Harvard University (USA)
University of Queensland (Australia)
National Chung Hsing University (Taiwan)
Universitas islam negeri Jakarta (Indonesia)
University of Hawaii Cancer Center (USA)
University of Stirling (United Kingdom)
National Cancer Center Research Institute (Japan)
Institute of Pathophysiology Medical University of Vienna (Austria)
University of Bonn (Germany)
More...
国外学术期刊发表的引用ChemFaces产品的部分文献
| Description: |
Ungeremine is a potential biofungicide against Penicillium roqueforti and Aspergillus niger, it has strong antibacterial activity against Flavobacterium columnare. Ungeremine also has antiprotozoal activity, it shows good activity in in vitro assays against Trypanosoma brucei rhodesiense, T. cruzi. Ungeremine effectively targets mammalian as well as bacterial type I and type II topoisomerases. Ungeremine also shows strong acetylcholinesterase inhibitory activity(IC(50) value of 0.35 microM). |
| Targets: |
Topoisomerase | Antifection | AChR |
| In vitro: |
| Nat Prod Res. 2018 Jul;32(13):1605-1610. | | Antimould microbial and plant metabolites with potential use in intelligent food packaging.[Pubmed: 29027475] | Moulds food infestation is a heavy dangerous problem for human health and also could generate heavy economic losses.
METHODS AND RESULTS:
The intelligent packaging using eco-friendly biodegradable biofilm incorporating bioactive natural safe compounds represents a new frontier. This manuscript reports the inhibitory activity of 12 bacterial, fungal and plant metabolites against Penicillium roqueforti and Aspergillus niger. Among them α-costic acid and Ungeremine (3 and 12) are the most promising as potential biofungicide against both fungal strains. They inhibited fungal growth by more than 60% respect to the control at 72 h and this activity persisted also at 96 h.
CONCLUSIONS:
Ungeremine showed MIC90 lower than 0.003 mg/mL after 48 h of incubation and of 0.025 mg/mL at 72 h against P. roqueforti. The MIC90 value for A. niger was 0.2 mg/mL at 48 h for both compounds. The α-costic acid showed generally MIC values at 48 and 72 h higher than Ungeremine. | | Phytochemistry Letters, 2010, 3(3):161-163. | | In vitro antiprotozoal activity of alkaloids from Phaedranassa dubia (Amaryllidaceae)[Reference: WebLink] | The bulbs of Phaedranassa dubia (Amaryllidaceae) were found to contain the novel compound phaedranamine, together with seven known alkaloids.
METHODS AND RESULTS:
The structure and stereochemistry of the alkaloids were determined by physical and spectroscopic methods. An in vitro screening against four different parasitic protozoa was carried out using the isolated compounds.
CONCLUSIONS:
The alkaloids Ungeremine, pseudolycorine and haemanthamine showed good activity in in vitro assays against Trypanosoma brucei rhodesiense, T. cruzi and Plasmodium falciparum with IC50 values in the range of 3.66 μM or lower. |
|
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
3.7556 mL |
18.7779 mL |
37.5559 mL |
75.1117 mL |
93.8897 mL |
| 5 mM |
0.7511 mL |
3.7556 mL |
7.5112 mL |
15.0223 mL |
18.7779 mL |
| 10 mM |
0.3756 mL |
1.8778 mL |
3.7556 mL |
7.5112 mL |
9.389 mL |
| 50 mM |
0.0751 mL |
0.3756 mL |
0.7511 mL |
1.5022 mL |
1.8778 mL |
| 100 mM |
0.0376 mL |
0.1878 mL |
0.3756 mL |
0.7511 mL |
0.9389 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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