Taxin B

	产品编号	CFN96637
	CAS编号	168109-52-2
	分子式 = 分子量	C₂₈H₃₈O₁₀ = 534.60
	产品纯度	>=98%
	物理属性	Powder
	化合物类型	Diterpenoids
	植物来源	The seeds of Taxus mairei.
ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用

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产品名称	产品编号	CAS编号	包装	QQ客服
Taxin B	CFN96637	168109-52-2	1mg	QQ客服：215959384
Taxin B	CFN96637	168109-52-2	5mg	QQ客服：215959384
Taxin B	CFN96637	168109-52-2	10mg	QQ客服：215959384
Taxin B	CFN96637	168109-52-2	20mg	QQ客服：215959384

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ChemFaces的产品在许多优秀和顶级科学期刊中被引用

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
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Cell Metab. 2020 Mar 3;31(3):534-548.e5.
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ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
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doi: 10.1038/nplants.2016.205.
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Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089

Korea Intitute of Science and Technology (KIST) (Korea)

Celltrion Chemical Research Institute (Korea)

Sapienza University of Rome (Italy)

Funda??o Universitária de Desenvolvimento (Brazil)

National Cancer Institute (USA)

Semmelweis Unicersity (Hungary)

Sanford Burnham Medical Research Institute (USA)

Aveiro University (Portugal)

Medizinische Universit?t Wien (Austria)

Leibniz Institute of Plant Biochemistry (Germany)

Nicolaus Copernicus Uniwersity (Poland)

Universidad Veracuzana (Mexico)

Massachusetts General Hospital (USA)

Universidade do Porto (Portugal)

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Description:

Taxin B has toxic effects.

In vivo:

Neuro Endocrinol Lett. 2013;34 Suppl 2:130-3.

Yew poisoning of olive baboons (Papio anubis) in captivity: laboratory diagnosis.[Pubmed: 24362105]

Toxic effects of the yew have been known since ancient times. Yew toxicity is due to the content of cyanogenic glycosides and a mixture of alkaloids known as taxines. Taxine B is probably responsible for the most part of adverse effects in poisoned organisms. This particular taxoid is common in body fluids of the yew-poisoned. The present study is engaged with laboratory examination to confirm substances that lead to fatality of a pair of olive baboons (Papio anubis) following ingestion of yew seeds. When both cage mates (male and female) died suddenly, poisoning was suspected because many berries had fallen into the cage from a nearby fruiting yew tree (Taxus baccata) during the windy night before.
METHODS AND RESULTS:
The analysis was performed using electrospray ionization quadrupole time-of-flight mass spectrometry. A flow injection analysis/mass spectrometry setting was prepared for this purpose. The above mentioned mass spectrometry analysis of taxoids confirmed poisoning by taxanes. The presence of Taxin B/isoTaxin B was confirmed in all investigated samples. Apparently in urine and bile there were concentrations ranging 150-220 ng.mL-1 and in blood serum concentrations 25-30 ng.mL-1.
CONCLUSIONS:
It follows from the results obtained that we confirmed that baboons were deadly intoxicated by yew fruits.

产品名称	产品编号	CAS编号	分子式 = 分子量	位单	联系QQ
neo-吐昔灵; neo-Truxilline	CFN00235	113350-54-2	C₃₈H₄₆N₂O₈ = 658.78	5mg	QQ客服：2056216494
乙酸糠酯; Furfuryl acetate	CFN70174	623-17-6	C₇H₈O₃ = 140.1	20mg	QQ客服：1413575084
盐酸法舒地尔; Fasudil Hydrochloride	CFN60076	105628-07-7	C₁₄H₁₇N₃O₂S.HCl = 327.83	5mg	QQ客服：215959384
毛果天芥菜碱; Lasiocarpine	CFN00289	303-34-4	C₂₁H₃₃NO₇ = 411.49	5mg	QQ客服：2159513211

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	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.8706 mL	9.3528 mL	18.7056 mL	37.4111 mL	46.7639 mL
5 mM	0.3741 mL	1.8706 mL	3.7411 mL	7.4822 mL	9.3528 mL
10 mM	0.1871 mL	0.9353 mL	1.8706 mL	3.7411 mL	4.6764 mL
50 mM	0.0374 mL	0.1871 mL	0.3741 mL	0.7482 mL	0.9353 mL
100 mM	0.0187 mL	0.0935 mL	0.1871 mL	0.3741 mL	0.4676 mL