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  • 大豆皂苷Bd

    • 大豆皂苷Bd

    Soyasaponin Bd

    大豆皂苷Bd
    		产品编号 CFN90775
    CAS编号 135272-91-2
    分子式 = 分子量 C48H76O19 = 957.1
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Triterpenoids
    植物来源 The seeds of Glycine max
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    大豆皂苷Bd CFN90775 135272-91-2 1mg QQ客服：2056216494
    大豆皂苷Bd CFN90775 135272-91-2 5mg QQ客服：2056216494
    大豆皂苷Bd CFN90775 135272-91-2 10mg QQ客服：2056216494
    大豆皂苷Bd CFN90775 135272-91-2 20mg QQ客服：2056216494
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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    • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Int J Mol Sci.2021, 22(12):6466.
  • Korean Journal of Pharmacognosy2018, 49(1):76-83
  • Int J Mol Sci.2023, 24(22):16465.
  • Sains Malaysiana2024, 53(4):795-805
  • J Immunol.2023, ji2200727.
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  • J Cachexia Sarcopenia Muscle.2022, 13(6):3149-3162.
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  • LWT-Food Science and Technology2017, 75:488-496
  • Exp Mol Med.2020, 52(4):629-642.
  • Nanjing University of Chinese Medicine2022, 345930.
  • Molecules.2022, 27(22):7997.
  • Pharmaceuticals (Basel).2022, 15(5):591.
  • Eur J Pharmacol.2021, 899:174010.
  • Biosci Rep.2020, 40(8):BSR20201219.
  • Nutraceutical Research . 2021, 19(1),p90-105.
  • Genes Genomics.2020, 10.1007
  • Evid Based Complement Alternat Med.2018, 2018:8565132
  • Bull. Pharm. Sci., Assiut University2020, 43(2):149-155.
  • Oncology Letters2018, 4690-4696
  • Int J Mol Sci.2020, 21(7):2530.
  • ...
    • 生物活性
    Description: 1. Soyasaponins has chemoprevention activities, it prevent H₂O₂-induced inhibition of gap junctional intercellular communication by scavenging reactive oxygen species in rat liver cells.
    2. Soyasaponins can significantly decrease blood glucose, improve atherosclerotic index, and inhibit lipid peroxidation and platelet aggregation in diabetic rats, which may be useful in prevention and control of diabetes mellitus and diabetes-associated atherosclerosis.
    3. Soyasaponins abundant in soybean have anti-inflammatory activities, low-dose SSs alleviated contact hypersensitivity (CHS) symptoms by attenuating inflammation and improving the intestinal microbiota composition, suggesting that dietary SSs may have beneficial effects on allergic contact dermatitis (ACD).
    4. Dietary soyasaponin has inhibitory effects on 2,4-dinitrofluorobenzene-induced contact hypersensitivity in mice.
    Targets: ROS | Immunology & Inflammation related
    In vitro:
    J Enzyme Inhib Med Chem . 2019 Dec;34(1):350-360.
    Soyasaponins from Zolfino bean as aldose reductase differential inhibitors[Pubmed: 30734590]
    Abstract Seven triterpenoid saponins were identified in methanolic extracts of seeds of the Zolfino bean landrace (Phaseolus vulgaris L.) by HPLC fractionation, revealing their ability to inhibit highly purified human recombinant aldose reductase (hAKR1B1). Six of these compounds were associated by MS analysis with the following saponins already reported in different Phaseolus vulgaris varieties: soyasaponin Ba (V), soyasaponin Bb, soyasaponin Bd (sandosaponin A), soyasaponin αg, 3-O-[R-l-rhamnopyranosyl(1 → 2)-α-d-glucopyranosyl(1 → 2)-α-d-glucuronopyranosyl]olean-12-en-22-oxo-3α,-24-diol, and soyasaponin βg. The inhibitory activity of the collected fractions containing the above compounds was tested for hAKR1B1-dependent reduction of both l-idose and 4-hydroxynonenal, revealing that some are able to differentially inhibit the enzyme. The present work also highlights the difficulties in the search for aldose reductase differential inhibitors (ARDIs) in mixtures due to the masking effect on ARDIs exerted by the presence of conventional aldose reductase inhibitors. The possibility of differential inhibition generated by a different inhibitory model of action of molecules on different substrates undergoing transformation is also discussed. Keywords: Saponins; Zolfino bean; aldose reductase; differential inhibitors.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.0448 mL 5.2241 mL 10.4482 mL 20.8965 mL 26.1206 mL
    5 mM 0.209 mL 1.0448 mL 2.0896 mL 4.1793 mL 5.2241 mL
    10 mM 0.1045 mL 0.5224 mL 1.0448 mL 2.0896 mL 2.6121 mL
    50 mM 0.0209 mL 0.1045 mL 0.209 mL 0.4179 mL 0.5224 mL
    100 mM 0.0104 mL 0.0522 mL 0.1045 mL 0.209 mL 0.2612 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    大豆皂苷IV; Soyasaponin IV CFN93251 108906-97-4 C41H66O13 = 767.0 5mg QQ客服：2056216494
    大豆皂苷 III; Soyasaponin III CFN91596 55304-02-4 C42H68O14 = 796.99 5mg QQ客服：1413575084
    大豆皂苷II; Soyasaponin II CFN93159 55319-36-3 C47H76O17 = 913.1 5mg QQ客服：2159513211
    大豆皂苷Bb; Soyasaponin Bb CFN90456 51330-27-9 C48H78O18 = 943.12 20mg QQ客服：1457312923
    大豆皂苷 Ba; Soyasaponin Ba CFN90722 114590-20-4 C48H78O19 = 959.1 20mg QQ客服：2159513211
    大豆皂苷Aa; Soyasaponin Aa CFN90455 117230-33-8 C64H100O31 = 1365.46 5mg QQ客服：1413575084
    大豆皂苷Ab; Soyasaponin Ab CFN90773 118194-13-1 C67H104O33 = 1437.6 5mg QQ客服：1457312923
    大豆皂苷Ac; Soyasaponin Ac CFN90774 133882-74-3 C67H104O32 = 1421.6 5mg QQ客服：215959384
    Pedunsaponin C ; Pedunsaponin C CFN80325 272120-53-3 C42H66O14 = 795.0 5mg QQ客服：2056216494
    Pedunsaponin A; Pedunsaponin A CFN80329 250613-27-5 C42H66O15 = 811.0 5mg QQ客服：1413575084

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