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  • 山梨酸

    Sorbic acid

    山梨酸
    产品编号 CFN90061
    CAS编号 110-44-1
    分子式 = 分子量 C6H8O2 = 112.13
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Miscellaneous
    植物来源 The berries of Sorbus aucuparia
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    山梨酸 CFN90061 110-44-1 10mg QQ客服:3257982914
    山梨酸 CFN90061 110-44-1 20mg QQ客服:3257982914
    山梨酸 CFN90061 110-44-1 50mg QQ客服:3257982914
    山梨酸 CFN90061 110-44-1 100mg QQ客服:3257982914
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Harvard University (USA)
  • Ateneo de Manila University (Philippines)
  • Hamdard University (India)
  • Universidade da Beira Interior (Germany)
  • Aveiro University (Portugal)
  • Florida International University (USA)
  • Heidelberg University (Germany)
  • Universidade do Porto (Portugal)
  • Complutense University of Madrid (Spain)
  • Universidad de Ciencias y Artes de Chiapas (Mexico)
  • China Medical University (Taiwan)
  • University of South Australia (Australia)
  • Universidade Federal de Goias (UFG) (Brazil)
  • Fraunhofer-Institut für Molekularbiologie und Angewandte ?kologie IME (Germany)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Industrial Crops and Products2022, 188:115638
  • Biomedicine & Pharmacotherapy2022, 153:113404.
  • Wageningen University & Research2018, January 2018
  • Biochem Pharmacol.2020, 178:114083
  • Hum Exp Toxicol.2017, 36(11):1169-1176
  • Biol Pharm Bull.2018, 41(1):65-72
  • Phytomedicine.2015, 22(4):498-503
  • Journal of Apiculture2023.38(3):249-254.
  • Int J Mol Sci.2020, 21(7):2530.
  • Journal of Functional Foods2022, 98:105271.
  • South African Journal of Botany2021, 142:114-123.
  • J Sep Sci.2019, 42(21):3352-3362
  • Separations2023, 10(11), 567;
  • Exp Parasitol.2017, 183:160-166
  • Food Funct.2020, 11(2):1322-1333.
  • Analytical Letters.2020, doi 10.1008
  • Evid Based Complement Alternat Med.2016, 2016:1230294
  • J Sci Food Agric.2024, 104(7):4425-4437.
  • Heliyon.2022, e12337.
  • Res Rep Urol.2022, 14:313-326.
  • SRM Institute of Sci&Tech2022, 34(1): 32-37
  • Preprints2022, 2022030063.
  • Journal of Ginseng Research2024, 03.005.
  • ...
  • 生物活性
    Description: Sorbic acid is important food preservatives and powerful fungistatic agents, it inhibits various bacteria, including sporeformers, at various stages of their life cycle (germination, outgrowth and cell division). Sorbic acid is a more potent uncoupler of the membrane potential than acetic acid, the effect may also slow the rate of ATP synthesis significantly and may thus (partially) explain Sorbic acid's effectiveness.
    Targets: Antifection | ATP | MAPK
    In vitro:
    Appl Environ Microbiol. 2014 Oct;80(19):5918-26.
    Distinct effects of sorbic acid and acetic acid on the electrophysiology and metabolism of Bacillus subtilis.[Pubmed: 25038097]
    Sorbic acid and acetic acid are among the weak organic acid preservatives most commonly used to improve the microbiological stability of foods. They have similar pKa values, but sorbic acid is a far more potent preservative. Weak organic acids are most effective at low pH. Under these circumstances, they are assumed to diffuse across the membrane as neutral undissociated acids.
    METHODS AND RESULTS:
    We show here that the level of initial intracellular acidification depends on the concentration of undissociated acid and less on the nature of the acid. Recovery of the internal pH depends on the presence of an energy source, but acidification of the cytosol causes a decrease in glucose flux. Furthermore, sorbic acid is a more potent uncoupler of the membrane potential than acetic acid.
    CONCLUSIONS:
    Together these effects may also slow the rate of ATP synthesis significantly and may thus (partially) explain sorbic acid's effectiveness.
    Appl Environ Microbiol. 2012 Dec;78(23):8477-80.
    Impact of sorbic acid on germination and outgrowth heterogeneity of Bacillus cereus ATCC 14579 spores.[Pubmed: 23001664]
    Population heterogeneity complicates the predictability of the outgrowth kinetics of individual spores.
    METHODS AND RESULTS:
    Flow cytometry sorting and monitoring of the germination and outgrowth of single dormant spores allowed the quantification of acid-induced spore population heterogeneity at pH 5.5 and in the presence of sorbic acid.
    CONCLUSIONS:
    This showed that germination efficiency was not a good predictor for heterogeneity in final outgrowth.
    J Food Sci Technol. 2014 Dec;51(12):4040-6.
    Effect of sorbic acid on the storage quality of Kaladhi -an acid coagulated milk product[Pubmed: 25477678]
    The present study was conducted to determine the effect of three different levels of sorbic acid (0.1 %, 0.2 % and 0.3 %) on the shelf life and storage quality of Kaladhi.
    METHODS AND RESULTS:
    Kaladhi was prepared from pasteurized buffalo milk standardized to 6 % fat and 9 % SNF with coagulation at 40 °C using 5 % lactic acid as a coagulant. Kaladhi prepared without sorbic acid served as control and was compared with the products treated with different levels of sorbic acid for a storage period of 35 days at ambient temperature. The results showed a significant (P < 0.05) effect of sorbic acid on most of the physicochemical parameters i.e. titratable acidity, free fatty acid content (% oleic acid) and thiobarbituric acid value which showed a decreasing trend with increasing concentration of sorbic acid. However, a non-significant (P > 0.05) effect of sorbic acid was observed on pH and proximate parameters of the product. Kaladhi treated with 0.3 % sorbic acid retained most desirable physicochemical and sensory properties throughout the storage period hence, was considered the best.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 8.9182 mL 44.5911 mL 89.1822 mL 178.3644 mL 222.9555 mL
    5 mM 1.7836 mL 8.9182 mL 17.8364 mL 35.6729 mL 44.5911 mL
    10 mM 0.8918 mL 4.4591 mL 8.9182 mL 17.8364 mL 22.2955 mL
    50 mM 0.1784 mL 0.8918 mL 1.7836 mL 3.5673 mL 4.4591 mL
    100 mM 0.0892 mL 0.4459 mL 0.8918 mL 1.7836 mL 2.2296 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    山梨酸; Sorbic acid CFN90061 110-44-1 C6H8O2 = 112.13 20mg QQ客服:2159513211
    正庚醛肟; Heptanal oxime CFN90121 629-31-2 C7H15NO = 129.20 5mg QQ客服:2056216494
    二烯丙基二硫醚; Diallyl disulfide CFN93237 2179-57-9 C6H10S2 = 146.3 20mg QQ客服:2056216494
    大蒜素; Allicin CFN90201 539-86-6 C6H10S2O = 162.27 20mg QQ客服:2159513211
    莱菔硫烷; 萝卜硫素; Sulforaphane CFN90203 4478-93-7 C6H11NOS2 = 177.29 5mg QQ客服:2159513211
    硫辛酸; Lipoic acid CFN99192 62-46-4 C8H14O2S2 = 206.3 20mg QQ客服:215959384
    顺铂; Cisplatin CFN93261 15663-27-1 Cl2H6N2Pt = 300.05 5mg QQ客服:215959384

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