绵枣儿素

Scillascillin

	产品编号	CFN98869
	CAS编号	52706-07-7
	分子式 = 分子量	C₁₇H₁₂O₆ = 312.3
	产品纯度	>=98%
	物理属性	Powder
	化合物类型	Flavonoids
	植物来源	The herbs of Scilla scilloides
ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用

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产品名称	产品编号	CAS编号	包装	QQ客服
绵枣儿素	CFN98869	52706-07-7	1mg	QQ客服：215959384
绵枣儿素	CFN98869	52706-07-7	5mg	QQ客服：215959384
绵枣儿素	CFN98869	52706-07-7	10mg	QQ客服：215959384
绵枣儿素	CFN98869	52706-07-7	20mg	QQ客服：215959384

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ChemFaces的产品在许多优秀和顶级科学期刊中被引用

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089

University of Maryland (USA)

Florida A&M University (USA)

Nicolaus Copernicus Uniwersity (Poland)

Rio de Janeiro State University (Brazil)

Center for protein Engineering (CIP) (Belgium)

National Research Council of Canada (Canada)

University of Illinois at Chicago (USA)

The Ohio State University (USA)

University of East Anglia (United Kingdom)

Wageningen University (Netherlands)

Leibniz Institute of Plant Biochemistry (Germany)

Universidad Miguel Hernández (Spain)

Yale University (USA)

Institute of Chinese Materia Medica (China)

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Description:

Scillascillin has anticancer activity, it is significantly active against human cancer cell lines MCF-7 (breast cancer) and DU-145 (prostate cancer) with inhibitory concentration (IC)50 values 9.59 and 11.32 ug/ml respectively.

In vitro:

Pharmacognosy Res. 2014 Oct;6(4):303-5.

Anticancer Active Homoisoflavone from the Underground Bulbs of Ledebouria hyderabadensis.[Pubmed: 25276067]

Ledebouria is a genus of deciduous or weakly evergreen bulbs in the Hyacinthaceae family. This is recognized as the first collection made of the new taxon Ledebouria hyderabadensis, exist in the Hyderabad city of Andhra Pradesh, India. The goal of this work was to investigate the phytochemical constituents present in the new specifies and also to evaluate the cytotoxic properties of the extracts and pure compounds against human cancer cell lines.
METHODS AND RESULTS:
The anticancer activity was evaluated in in vitro mode by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) test. Phytochemical investigation of underground bulbs of indigenous, rare, and recently identified herb L. hyderabadensis yielded a bioactive homoisoflavanone, Scillascillin 1. The structure of the compound was established on the basis of various nuclear magnetic resonance and mass spectral data. The compound Scillascillin was isolated for the first time from L. hyderabadensis.
CONCLUSIONS:
In vitro anticancer activity, performed using MTT assay, showed compound 1 as significantly active against human cancer cell lines MCF-7 (breast cancer) and DU-145 (prostate cancer) with inhibitory concentration (IC)50 values 9.59 and 11.32 μg/ml respectively when compared with herb methanol extract (IC50 values 36.21 and 44.86 μg/ml respectively).

产品名称	产品编号	CAS编号	分子式 = 分子量	位单	联系QQ
苏木酮B; Sappanone B	CFN92964	104778-15-6	C₁₆H₁₄O₆ = 302.28	5mg	QQ客服：3257982914
2-羟基-7-O-甲基绵枣儿素; 2-Hydroxy-7-O-methylscillascillin	CFN98844	52096-50-1	C₁₈H₁₄O₇ = 342.3	5mg	QQ客服：2159513211
绵枣儿素; Scillascillin	CFN98869	52706-07-7	C₁₇H₁₂O₆ = 312.3	5mg	QQ客服：215959384
7,3',4'-三羟基-3-苄基-2H-苯并吡喃; 7,3',4'-Trihydroxy-3-benzyl-2H-chromene	CFN99209	1111897-60-9	C₁₆H₁₄O₄ = 270.3	5mg	QQ客服：2159513211
表苏木酚; Episappanol	CFN92962	111254-18-3	C₁₆H₁₆O₆ = 304.29	5mg	QQ客服：2159513211
4-O-甲基表苏木酚; 4-O-Methylepisappanol	CFN92769	112529-37-0	C₁₇H₁₈O₆ = 318.3	5mg	QQ客服：2159513211
3'-去氧-4-O-甲基表苏木酚; 3'-Deoxy-4-O-methylepisappanol	CFN92771	1052714-12-1	C₁₇H₁₈O₅ = 302.3	5mg	QQ客服：1457312923
苏木酚; Sappanol	CFN92832	111254-19-4	C₁₆H₁₆O₆ = 304.3	5mg	QQ客服：3257982914
4-O-甲基蘇木黃素; 4-O-Methylsappanol	CFN99068	104778-16-7	C₁₇H₁₈O₆ = 318.3	5mg	QQ客服：3257982914
3'-去氧-4-O-甲基苏木酚; 3'-Deoxy-4-O-methylsappanol	CFN92770	112408-68-1	C₁₇H₁₈O₅ = 302.3	5mg	QQ客服：2056216494

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	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.202 mL	16.0102 mL	32.0205 mL	64.041 mL	80.0512 mL
5 mM	0.6404 mL	3.202 mL	6.4041 mL	12.8082 mL	16.0102 mL
10 mM	0.3202 mL	1.601 mL	3.202 mL	6.4041 mL	8.0051 mL
50 mM	0.064 mL	0.3202 mL	0.6404 mL	1.2808 mL	1.601 mL
100 mM	0.032 mL	0.1601 mL	0.3202 mL	0.6404 mL	0.8005 mL