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  • 蕨素Z

    Pterosin Z

    蕨素Z
    产品编号 CFN98442
    CAS编号 34169-69-2
    分子式 = 分子量 C15H20O2 = 232.3
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Sesquiterpenoids
    植物来源 The rhizomes of Cibotium barometz (L.) J.Sm.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    蕨素Z CFN98442 34169-69-2 1mg QQ客服:1457312923
    蕨素Z CFN98442 34169-69-2 5mg QQ客服:1457312923
    蕨素Z CFN98442 34169-69-2 10mg QQ客服:1457312923
    蕨素Z CFN98442 34169-69-2 20mg QQ客服:1457312923
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Aging (Albany NY).2021, 13(19):22867-22882.
  • Molecules.2022, 27(22):7887.
  • J. Soc. Cosmet. Sci. Korea2021, 47(1):57-63
  • Industrial Food Engineering2015, 19(4):408-413
  • Toxicol In Vitro.2022, 81:105346.
  • Journal of Third Military Medical University2018, 40(12):1073-1078
  • Molecules.2019, 24(4):E709
  • Cell Prolif.2021, 54(8):e13083.
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  • Korean Journal of Pharmacognosy2019, 50(4):285-290
  • Biochem Biophys Res Commun.2017, 494(3-4):587-593
  • Int J Mol Sci.2019, 20(14):E3538
  • Biol Pharm Bull.2018, 41(1):65-72
  • J of Pharmaceutical Analysis2020, doi: 10.1016
  • Life Sci.2022, 298:120488.
  • Anat Rec2018, 24264
  • Cancers (Basel).2021, 13(9):2223.
  • Natural Product Communications2020, doi: 10.1177.
  • Yakugaku Zasshi.2018, 138(4):571-579
  • Research Square2021, March 3rd.
  • Evid Based Complement Alternat Med.2018, 2018:1073509
  • Int. J. Mol. Sci.2022, 23(19), 11900.
  • Journal of Apiculture2019, 34(2):131-136
  • ...
  • 生物活性
    Description: Pterosin Z has smooth muscle relaxant activity, is approximately equipotent with that of the related fungal pterosin (EC50 of 2.9 +/- 1.6 x 10(-6) M).
    Targets: Calcium Channel
    In vitro:
    Planta Med. 1999 Apr;65(3):271-2.
    Smooth muscle relaxant activity of pterosin Z and related compounds.[Pubmed: 10232079]

    METHODS AND RESULTS:
    The natural products Pterosin Z, acetylPterosin Z, originally from the fern Pteridium aquilinum, and their isopterosin analogues have been synthesized and their smooth muscle relaxation activity has been measured. All of the test compounds show activity with Pterosin Z being the most active (EC50 = 1.3 +/- 0.1 x 10(-6) M), exhibiting 100 times the activity reported for the related fern metabolites onitin (EC50 = 1 x 10(-4) M), onotisin (EC50 = 2 x 10(-3) M) and otninoside (EC50 = 7 x 10(-4) M). The smooth muscle relaxant activity of Pterosin Z is approximately equipotent with that of the related fungal pterosin (EC50 of 2.9 +/- 1.6 x 10(-6) M).
    CONCLUSIONS:
    These results suggest that smooth muscle relaxant activity is reduced when a phenol group is present in the pterosin nucleus and when one of the dimethyl groups is derivatized.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.3048 mL 21.5239 mL 43.0478 mL 86.0956 mL 107.6195 mL
    5 mM 0.861 mL 4.3048 mL 8.6096 mL 17.2191 mL 21.5239 mL
    10 mM 0.4305 mL 2.1524 mL 4.3048 mL 8.6096 mL 10.7619 mL
    50 mM 0.0861 mL 0.4305 mL 0.861 mL 1.7219 mL 2.1524 mL
    100 mM 0.043 mL 0.2152 mL 0.4305 mL 0.861 mL 1.0762 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    金粉蕨亭2'-O-葡萄糖苷; Onitin 2'-O-glucoside CFN97251 76947-60-9 C21H30O8 = 410.5 5mg QQ客服:2159513211
    金粉蕨辛; Onitisin CFN98899 53823-03-3 C15H20O4 = 264.3 5mg QQ客服:2056216494
    金粉蕨辛2'-O-葡萄糖苷; Onitisin 2'-O-glucoside CFN97066 62043-53-2 C21H30O9 = 426.5 5mg QQ客服:2056216494
    蕨素Z; Pterosin Z CFN98442 34169-69-2 C15H20O2 = 232.3 5mg QQ客服:3257982914
    蕨素A; Pterosin A CFN80051 35910-16-8 C15H20O3 = 248.14 5mg QQ客服:1413575084
    蕨苷A; Pteroside A CFN80184 35910-15-7 C21H30O8 = 410.19 5mg QQ客服:1457312923
    蕨素D; Pterosin D CFN98443 34169-70-5 C15H20O3 = 248.3 5mg QQ客服:1457312923
    Pterolactone A; Pterolactone A CFN96247 74730-10-2 C15H16O4 = 260.3 5mg QQ客服:1413575084
    蕨苷D; Pteroside D CFN98485 35943-38-5 C21H30O8 = 410.5 5mg QQ客服:1457312923
    表蕨素D 3-O-葡萄糖苷; Pterosin D 3-O-glucoside CFN97608 84299-80-9 C21H30O8 = 410.46 5mg QQ客服:3257982914

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