脯氨酸

Proline

	产品编号	CFN99612
	CAS编号	147-85-3
	分子式 = 分子量	C₅H₉NO₂ = 115.1
	产品纯度	>=98%
	物理属性	Powder
	化合物类型	Alkaloids
	植物来源	The herbs of Gynura japonica
ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用

提供自定义包装

产品名称	产品编号	CAS编号	包装	QQ客服
脯氨酸	CFN99612	147-85-3	10mg	QQ客服：2159513211
脯氨酸	CFN99612	147-85-3	20mg	QQ客服：2159513211
脯氨酸	CFN99612	147-85-3	50mg	QQ客服：2159513211
脯氨酸	CFN99612	147-85-3	100mg	QQ客服：2159513211

存储与注意事项

1. 在您收到产品后请检查产品。如无问题，请将产品存入冰霜并且样品瓶保持密封，产品可以存放长达24个月（2-8摄氏度）。

2. 只要有可能，产品溶解后，您应该在同一天应用于您的实验。但是，如果您需要提前做预实验，或者需要全部溶解，我们建议您将溶液以等分试样的形式存放在-20℃的密封小瓶中。通常，这些可用于长达两周。使用前，打开样品瓶前，我们建议您将产品平衡至室温至少1小时。

3. 需要更多关于溶解度，使用和处理的建议？请发送电子邮件至：service@chemfaces.com

订购流程

1. 在线订购

请联系我们QQ客服

2. 电话订购

请拨打电话：
027-84237683 或 027-84237783

3. 邮件或传真订购

发送电子邮件到: manager@chemfaces.com 或
发送传真到：027-84254680

提供订购信息

为了方便客户的订购，请需要订购ChemFaces产品的客户，在下单的时候请提供下列信息，以供我们快速为您建立发货信息。

1. 产品编号（CAS No.或产品名称）

2. 发货地址

3. 联系方法 (联系人，电话）

4. 开票抬头 (如果需要发票的客户）

5. 发票地址（发货地址与发票地址不同）

发货时间

1. 付款方式为100%预付款客户，我们将在确认收到货款后当天或1-3个工作日发货。

2. 付款方式为月结的客户，我们承诺在收到订单后当天或1-3个工作日内发货。

3. 如果客户所需要的产品，需要重新生产，我们有权告知客户，交货时间需要延期。

ChemFaces的产品在许多优秀和顶级科学期刊中被引用

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089

Universidad de La Salle (Mexico)

Semmelweis Unicersity (Hungary)

University of Wollongong (Australia)

University of Illinois (USA)

Universite de Lille1 (France)

Shanghai Institute of Biochemistry and Cell Biology (China)

Institute of Tropical Disease Universitas Airlangga (Indonesia)

Donald Danforth Plant Science Center (USA)

The Vancouver Prostate Centre (VPC) (Canada)

Universidade Católica Portuguesa (Portugal)

Utah State University (USA)

University of Ioannina (Greece)

Biotech R&D Institute (USA)

Universidad de Buenos Aires (Argentina)

More...

Description:

L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.Proline accumulates in many plant species in response to environmental stress, it can act as a signaling molecule to modulate mitochondrial functions, influence cell proliferation or cell death and trigger specific gene expression, which can be essential for plant recovery from stress, the engineering of proline metabolism could lead to new opportunities to improve plant tolerance of environmental stresses.

Targets:

p38MAPK | HIF

In vitro:

Science. 2001 Apr 20;292(5516):464-8.

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing.[Pubmed: 11292862 ]

HIF (hypoxia-inducible factor) is a transcription factor that plays a pivotal role in cellular adaptation to changes in oxygen availability. In the presence of oxygen, HIF is targeted for destruction by an E3 ubiquitin ligase containing the von Hippel-Lindau tumor suppressor protein (pVHL). We found that human pVHL binds to a short HIF-derived peptide when a conserved proline residue at the core of this peptide is hydroxylated. Because proline hydroxylation requires molecular oxygen and Fe(2+), this protein modification may play a key role in mammalian oxygen sensing.

In vivo:

Trends Plant Sci. 2010 Feb;15(2):89-97.

Proline: a multifunctional amino acid.[Pubmed: 20036181 ]

Proline accumulates in many plant species in response to environmental stress. Although much is now known about proline metabolism, some aspects of its biological functions are still unclear. Here, we discuss the compartmentalization of proline biosynthesis, accumulation and degradation in the cytosol, chloroplast and mitochondria. We also describe the role of proline in cellular homeostasis, including redox balance and energy status. Proline can act as a signaling molecule to modulate mitochondrial functions, influence cell proliferation or cell death and trigger specific gene expression, which can be essential for plant recovery from stress. Although the regulation and function of proline accumulation are not yet completely understood, the engineering of proline metabolism could lead to new opportunities to improve plant tolerance of environmental stresses.

产品名称	产品编号	CAS编号	分子式 = 分子量	位单	联系QQ
5-羟基-2-吡咯烷酮; 5-Hydroxy-2-pyrrolidinone	CFN97072	62312-55-4	C₄H₇NO₂ = 101.1	5mg	QQ客服：3257982914
蕨内酰胺; Pterolactam	CFN98614	38072-88-7	C₅H₉NO₂ = 115.1	5mg	QQ客服：1457312923
盐酸水苏碱; Stachydrine hydrochloride	CFN98506	4136-37-2	C₇H₁₄ClNO₂ = 179.64	20mg	QQ客服：2159513211
脯氨酸; Proline	CFN99612	147-85-3	C₅H₉NO₂ = 115.1	20mg	QQ客服：2056216494
去甲基烟碱; Nornicotine	CFN80056	494-97-3	C₉H₁₂N₂ = 148.10	5mg	QQ客服：1457312923
L-尼古丁; L-Nicotine	CFN99512	54-11-5	C₁₀H₁₄N₂ = 162.23	20mg	QQ客服：2159513211
(1'S.2'S)-尼古丁1'-氧化物 ; Nicotine 1'-N-oxide	CFN96582	51095-86-4	C₁₀H₁₄N₂O = 178.23	5mg	QQ客服：2056216494
Aglain C; Aglain C	CFN96309	177468-85-8	C₃₆H₄₂N₂O₈ = 630.7	5mg	QQ客服：3257982914
Aglain B; Aglain B	CFN96344	177262-32-7	C₃₆H₄₂N₂O₈ = 630.7	5mg	QQ客服：1457312923
Aglaxiflorin D; Aglaxiflorin D	CFN96299	269739-78-8	C₃₆H₄₂N₂O₉ = 646.7	5mg	QQ客服：3257982914

信息支持

公司简介
订购流程
付款方式
退换货政策

ChemFaces提供的产品仅用于科学研究使用，不用于诊断或治疗程序。

联系方式

电机：027-84237783
传真：027-84254680
在线QQ: 1413575084
E-Mail：manager@chemfaces.com

湖北省武汉沌口经济技术开区车城南路83号1号楼第三层厂房

ChemFaces为科学家，科研人员与企业提供快速的产品递送。我们通过瑞士SGS ISO 9001:2008质量体系认证天然化合物与对照品的研发和生产。

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	8.6881 mL	43.4405 mL	86.881 mL	173.7619 mL	217.2024 mL
5 mM	1.7376 mL	8.6881 mL	17.3762 mL	34.7524 mL	43.4405 mL
10 mM	0.8688 mL	4.344 mL	8.6881 mL	17.3762 mL	21.7202 mL
50 mM	0.1738 mL	0.8688 mL	1.7376 mL	3.4752 mL	4.344 mL
100 mM	0.0869 mL	0.4344 mL	0.8688 mL	1.7376 mL	2.172 mL