| In vitro: |
| Phytotherapy Research, 2010, 4(6):232-234. | | CNS activity of Mentha rotundifolia and Mentha longifolia essential oil in mice and rats.[Reference: WebLink] |
METHODS AND RESULTS:
The essential oils of Mentha rotundifolia and Mentha longifolia were analyzed with GC and GC/MS. The major components were rotundifolone (10.4%) and piperitol (57.6%) in M. rotundifolia , and rotundifolone (33.2%) and diosphenol (47.7%) in M. longifolia. M. longifolia essential oil exhibited a stronger CNS depressant effect than that of M. rotundifolia ; both essential oils were somnifacients. | | Journal of Agricultural and Food Chemistry, 2011, 59(7):3214-3219. | | Identification of Methanol-Soluble Compounds in Sesame and Evaluation of Antioxidant Potential of Its Lignans.[Reference: WebLink] | The methanol extract of sesame (Sesamum indicum) seeds was fractionated and purified with the assistance of conventional column chromatography to afford 29 compounds including seven furofuran lignans. Among these isolates, (+)-samin (1) was obtained from the natural source for the first time. In addition, (-)-asarinin (30) and sesamol (31) were generated by oxidative derivation from (+)-sesamolin (2) and (+)-sesamin (3), two abundant lignans found in sesame seeds.
METHODS AND RESULTS:
To evaluate their in vitro antioxidant potential, the seven isolated lignans (1-7) and the two derivatives (30 and 31) were examined for the scavenging activities on DPPH free radicals and superoxide anions. Moreover, the capability of chelating ferrous ions and reducing power of these sesame lignans were also measured.
CONCLUSIONS:
The results suggest that, besides the well-known sesamolin and sesamin, the minor sesame lignans (+)-(7S,8'R,8R)-acuminatolide (5), (-)-piperitol (6), and (+)-pinoresinol (7) are also adequate active ingredients and may be potential sources for nutritional and pharmacological utilization. |
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Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)
