In vitro: |
Chem Pharm Bull (Tokyo). 1992 Sep;40(9):2325-30. | Indonesia medicinal plants. III. On the constituents of the bark of Fagara rhetza (Rutaceae). (1): Alkaloids, phenylpropanoids, and acid amide.[Pubmed: 1446354 ] |
METHODS AND RESULTS:
Two new phenylpropanoids, named O-geranylsinapyl alcohol (1) and O-Geranylconiferyl alcohol (2), and a new acid amide, named hazeleamide (3), were isolated from the bark of Fagara rhetza (Rutaceae), an Indonesian medicinal plant from Flores Island, Indonesia. The chemical structures of 1, O-Geranylconiferyl alcohol, and 3 have been elucidated on the basis of their chemical and physicochemical properties.
CONCLUSIONS:
Among the three new compounds, hazeleamide (3) was found to show a pungent taste and to exert a moderate antimalarial activity in an in vitro test system. |
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