Info: Read More
  • 中药标准品生产商,产品定制服务
  • Nardoaristolone B

    Nardoaristolone B

    Nardoaristolone B
    产品编号 CFN95203
    CAS编号 1422517-82-5
    分子式 = 分子量 C14H18O2 = 218.3
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Sesquiterpenoids
    植物来源 The roots of Nardostachys chinensis.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    Nardoaristolone B CFN95203 1422517-82-5 1mg QQ客服:2159513211
    Nardoaristolone B CFN95203 1422517-82-5 5mg QQ客服:2159513211
    Nardoaristolone B CFN95203 1422517-82-5 10mg QQ客服:2159513211
    Nardoaristolone B CFN95203 1422517-82-5 20mg QQ客服:2159513211
    存储与注意事项
    1. 在您收到产品后请检查产品。如无问题,请将产品存入冰霜并且样品瓶保持密封,产品可以存放长达24个月(2-8摄氏度)。

    2. 只要有可能,产品溶解后,您应该在同一天应用于您的实验。 但是,如果您需要提前做预实验,或者需要全部溶解,我们建议您将溶液以等分试样的形式存放在-20℃的密封小瓶中。 通常,这些可用于长达两周。 使用前,打开样品瓶前,我们建议您将产品平衡至室温至少1小时。

    3. 需要更多关于溶解度,使用和处理的建议? 请发送电子邮件至:service@chemfaces.com
    订购流程
  • 1. 在线订购
  • 请联系我们QQ客服

  • 2. 电话订购
  • 请拨打电话:
    027-84237683 或 027-84237783

  • 3. 邮件或传真订购
  • 发送电子邮件到: manager@chemfaces.com 或
    发送传真到:027-84254680

  • 提供订购信息
  • 为了方便客户的订购,请需要订购ChemFaces产品的客户,在下单的时候请提供下列信息,以供我们快速为您建立发货信息。
  •  
  • 1. 产品编号(CAS No.或产品名称)
  • 2. 发货地址
  • 3. 联系方法 (联系人,电话)
  • 4. 开票抬头 (如果需要发票的客户)
  • 5. 发票地址(发货地址与发票地址不同)
  • 发货时间
    1. 付款方式为100%预付款客户,我们将在确认收到货款后当天或1-3个工作日发货。

    2. 付款方式为月结的客户,我们承诺在收到订单后当天或1-3个工作日内发货。

    3. 如果客户所需要的产品,需要重新生产,我们有权告知客户,交货时间需要延期。
    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Sanford Burnham Medical Research Institute (USA)
  • Monash University Malaysia (Malaysia)
  • University of Eastern Finland (Finland)
  • University of Indonesia (Indonesia)
  • University of Otago (New Zealand)
  • University of Maryland School of Medicine (USA)
  • Kyoto University (Japan)
  • University Medical Center Mainz (Germany)
  • Osmania University (India)
  • Kamphaengphet Rajabhat University (Thailand)
  • Universidade de Franca (Brazil)
  • University of Fribourg (Switzerland)
  • St. Jude Children Research Hospital (USA)
  • Max-Planck-Insitut (Germany)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Molecules.2023, 28(13):4971.
  • Pharmacognosy Journal2019, 11(2): 369-373
  • Applied Physics B2021, 127(92).
  • Naunyn Schmiedebergs Arch Pharmacol.2021, 394(1):107-115.
  • Int J Mol Sci.2021, 22(21):11836.
  • Chin J Appl. Physiol.2019, 35(3):283-288
  • BMC Complement Altern Med.2019, 19(1):11
  • 2023, 24(6):5769.Int J Mol Sci.
  • Oxid Med Cell Longev2019, 9056845:13
  • Int J Mol Med.2020, 45(5):1514-1524.
  • Food Quality and Safety2018, 2:213-219
  • National Academy Science Letters2023, s40009.
  • J Immunol.2023, ji2200727.
  • Int J Biol Macromol.2020, 169:342-351
  • Biomed Pharmacother.2023, 163:114785.
  • Pharmaceutics.2022, 14(3):564.
  • Molecules.2020, 25(23):5609.
  • Process Biochemistry2019, 85:106-115
  • J of Apicultural Research2020, 10.1080
  • Food Funct.2022, 13(14):7638-7649.
  • Molecules.2021, 26(3):695.
  • Institute of Food Science & Technology2021, 45(9).
  • Psychopharmacology (Berl).2020, 10.1007
  • ...
  • 生物活性
    Description: Nardoaristolone B, a nor-sesquiterpenoid with an unusual fused ring system and having protective effects on the injury of neonatal rat cardiomyocytes. The novel mosquito-repellentsynthetic hydrindanesbased on noreremophilanes and nardoaristolone B which show increasedactivity against adult females of Aedes aegypti.
    In vitro:
    Molecules. 2018 Sep 17;23(9). pii: E2367.
    Isolation of Novel Sesquiterpeniods and Anti-neuroinflammatory Metabolites from Nardostachys jatamansi.[Pubmed: 30227591]
    Nardostachys jatamansi contains various types of sesquiterpenoids that may play an important role in the potency of plant's anti-inflammatory effects, depending on their structure.
    METHODS AND RESULTS:
    In this study, five new sesquiterpenoids, namely kanshone L (1), kanshone M (2), 7-methoxydesoxo-narchinol (3), kanshone N (4), and nardosdaucanol (5), were isolated along with four known terpenoids (kanshone D (6), nardosinanone G (7), narchinol A (8), and nardoaristolone B (9)) from the rhizomes and roots of Nardostachys jatamansi. Their structures were determined by analyzing 1D and 2D NMR and MS data. Among the nine sesquiterpenoids, compounds 3, 4, and 8 were shown to possess dose-dependent inhibitory effects against lipopolysaccharide (LPS)-stimulated nitric oxide (NO) production in BV2 microglial cells. Furthermore, compounds 3, 4, and 8 exhibited anti-neuroinflammatory effects by inhibiting the production of pro-inflammatory mediators, including prostaglandin E₂ (PGE₂), inducible nitric oxide synthase (iNOS), and cyclooxygenase-2 (COX-2) proteins, as well as pro-inflammatory cytokines, such as interleukin (IL)-1β, IL-12 and tumor necrosis factor-α (TNF-α), in LPS-stimulated BV2 microglial cells. Moreover, these compounds were shown to inhibit the activation of the NF-κB signaling pathway in LPS-stimulated BV2 microglial cells by suppressing the phosphorylation of IκB-α and blocking NF-κB translocation.
    CONCLUSIONS:
    In conclusion, five new and four known sesquiterpenoids were isolated from Nardostachys jatamansi, and compounds 3, 4, and 8 exhibited anti-neuroinflammatory effects in LPS-stimulated BV2 microglial cells through inhibiting of NF-κB signaling pathway.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.5809 mL 22.9043 mL 45.8085 mL 91.617 mL 114.5213 mL
    5 mM 0.9162 mL 4.5809 mL 9.1617 mL 18.3234 mL 22.9043 mL
    10 mM 0.4581 mL 2.2904 mL 4.5809 mL 9.1617 mL 11.4521 mL
    50 mM 0.0916 mL 0.4581 mL 0.9162 mL 1.8323 mL 2.2904 mL
    100 mM 0.0458 mL 0.229 mL 0.4581 mL 0.9162 mL 1.1452 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    甘松新酮二醇; Nardosinonediol CFN89546 20489-11-6 C15H24O3 = 252.34 5mg QQ客服:3257982914
    异甘松新酮; Isonardosinone CFN95180 27062-01-7 C15H20O4 = 264.3 10mg QQ客服:2159513211
    Narchinol B; Narchinol B CFN89522 1356822-09-7 C12H16O3 = 208.25 5mg QQ客服:2056216494
    Desoxo-narchinol A; Desoxo-narchinol A CFN89358 53859-06-6 C12H16O2 = 192.25 5mg QQ客服:1457312923
    努特卡酮, 诺卡酮; Nootkatone CFN98699 4674-50-4 C15H22O = 218.3 20mg QQ客服:3257982914
    Oxyphyllol B; Oxyphyllol B CFN95575 226546-99-2 C15H22O2 = 234.3 5mg QQ客服:1413575084
    Tessaric acid; Tessaric acid CFN95182 58142-10-2 C15H20O3 = 248.3 5mg QQ客服:3257982914
    苷松新酮; Nardosinone CFN90178 23720-80-1 C15H22O3 = 250.33 20mg QQ客服:1457312923
    甘松香酮B ; Kanshone B CFN89423 115370-61-1 C15H22O4 = 266.33 5mg QQ客服:3257982914
    马兜铃酮; Aristolone CFN96139 6831-17-0 C15H22O = 218.3 20mg QQ客服:3257982914

    信息支持


    公司简介
    订购流程
    付款方式
    退换货政策

    ChemFaces提供的产品仅用于科学研究使用,不用于诊断或治疗程序。

    联系方式


    电机:027-84237783
    传真:027-84254680
    在线QQ: 1413575084
    E-Mail:manager@chemfaces.com

    湖北省武汉沌口经济技术开区车城南路83号1号楼第三层厂房


    ChemFaces为科学家,科研人员与企业提供快速的产品递送。我们通过瑞士SGS ISO 9001:2008质量体系认证天然化合物与对照品的研发和生产