脱镁叶绿酸A甲酯

Methylpheophorbide A

	产品编号	CFN91976
	CAS编号	5594-30-9
	分子式 = 分子量	C₃₆H₃₈N₄O₅ = 606.71
	产品纯度	>=98%
	物理属性	Powder
	化合物类型	Alkaloids
	植物来源	The herbs of Rubia cordifolia
ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用

提供自定义包装

产品名称	产品编号	CAS编号	包装	QQ客服
脱镁叶绿酸A甲酯	CFN91976	5594-30-9	1mg	QQ客服：1457312923
脱镁叶绿酸A甲酯	CFN91976	5594-30-9	5mg	QQ客服：1457312923
脱镁叶绿酸A甲酯	CFN91976	5594-30-9	10mg	QQ客服：1457312923
脱镁叶绿酸A甲酯	CFN91976	5594-30-9	20mg	QQ客服：1457312923

存储与注意事项

1. 在您收到产品后请检查产品。如无问题，请将产品存入冰霜并且样品瓶保持密封，产品可以存放长达24个月（2-8摄氏度）。

2. 只要有可能，产品溶解后，您应该在同一天应用于您的实验。但是，如果您需要提前做预实验，或者需要全部溶解，我们建议您将溶液以等分试样的形式存放在-20℃的密封小瓶中。通常，这些可用于长达两周。使用前，打开样品瓶前，我们建议您将产品平衡至室温至少1小时。

3. 需要更多关于溶解度，使用和处理的建议？请发送电子邮件至：service@chemfaces.com

订购流程

1. 在线订购

请联系我们QQ客服

2. 电话订购

请拨打电话：
027-84237683 或 027-84237783

3. 邮件或传真订购

发送电子邮件到: manager@chemfaces.com 或
发送传真到：027-84254680

提供订购信息

为了方便客户的订购，请需要订购ChemFaces产品的客户，在下单的时候请提供下列信息，以供我们快速为您建立发货信息。

1. 产品编号（CAS No.或产品名称）

2. 发货地址

3. 联系方法 (联系人，电话）

4. 开票抬头 (如果需要发票的客户）

5. 发票地址（发货地址与发票地址不同）

发货时间

1. 付款方式为100%预付款客户，我们将在确认收到货款后当天或1-3个工作日发货。

2. 付款方式为月结的客户，我们承诺在收到订单后当天或1-3个工作日内发货。

3. 如果客户所需要的产品，需要重新生产，我们有权告知客户，交货时间需要延期。

ChemFaces的产品在许多优秀和顶级科学期刊中被引用

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089

Semmelweis Unicersity (Hungary)

Instituto de Investigaciones Agropecuarias (Chile)

Instituto Politécnico de Bragan?a (Portugal)

Almansora University (Egypt)

Indian Institute of Science (India)

Universite Libre de Bruxelles (Belgium)

University of the Basque Country (Spain)

Sri Ramachandra University (India)

Molecular Biology Institute of Barcelona (IBMB)-CSIC (Spain)

Leibniz Institute of Plant Biochemistry (Germany)

Universidad Veracuzana (Mexico)

Universidade da Beira Interior (Germany)

Universiti Putra Malaysia(UPM) (Malaysia)

Mahidol University (Thailand)

More...

Description:

Methylphophorbide A shows antioxidative and anticarcinogenic activities.

In vitro:

Photodiagnosis Photodyn Ther. 2017 Mar;17:39-47.

Semi-synthesis and PDT activities of a new amphiphilic chlorin derivative.[Pubmed: 27769913]

An amphiphilic chlorin derivative (CHL-T) was prepared from Methylpheophorbide A (CHL) and 2-Amino-2-(hydroxymethyl)-1,3-propanediol (TRISMA®).
METHODS AND RESULTS:
The new chlorin was compared to other dyes (CHL and Hypericin) in relation to photophysical and photobiological activities in tumor and non-tumor cell lines. Cytotoxicity and cell death target were determined to evaluate the CHL-T efficiency, comparing to the precursor CHL and to the well-known dye hypericin (HY). All of the studied compounds exhibited absorption bands in the therapeutic window and presented a small fluorescence quantum yield compared to the reference dye (rhodamine B). CHL-T was about three times more efficient on singlet oxygen generation than the others photosensitizers. The lipophilicity order of the photosensitizers was CHL>HY>CHL-T. The tumoral HeLa cells presented improved accumulation for CHL and CHL-T compared to HY. The phototoxicity presented by the CHL-T was about ten times higher than by CHL, as demonstrated by the MTT assay. CHL-T showed more cytotoxicity to tumoral cell, comparing to non-tumoral cell in short incubation time. The cell death rises proportionally with increasing PSs concentrations, mainly by necrosis.
CONCLUSIONS:
These findings suggest that CHL-T is a potential new photosensitizer for PDT.

Nat Prod Res. 2016;30(4):474-7.

Antioxidative and anticarcinogenic activities of methylpheophorbide a, isolated from wheat grass (Triticum aestivum Linn.).[Pubmed: 25782530 ]

Methylphophorbide A (MPa) has been isolated from the ethanol extract of the wheat grass plant.
METHODS AND RESULTS:
Its antioxidative efficacy is evaluated by hydroxyl radical scavenging activities and reducing capacity which are significantly up regulated in comparison with aqueous extract of the plant. The compound shows iron-binding capacity where the Fe(2+) binds with MPa by two types of binding patterns with dissociation constants 157.17 and 27.89. It has antioxidative and cytotoxic effects on HeLa and Hep G2 cells. The cancerous cell survivability decreases with increasing concentration of MPa.
CONCLUSIONS:
These findings have provided evidence for the traditional use of the wheat grass plant in the treatment of cancers, oxidative stress and iron overloaded disorders.

产品名称	产品编号	CAS编号	分子式 = 分子量	位单	联系QQ
RA VII; RA VII	CFN92604	86229-97-2	C₄₁H₅₀N₆O₉ = 770.9	5mg	QQ客服：2159513211
RA-V; RA-V	CFN92605	64725-24-2	C₄₀H₄₈N₆O₉ = 756.9	5mg	QQ客服：2056216494
RA-XI; RA-XI	CFN92606	143277-27-4	C₄₂H₅₀N₆O₁₁ = 814.9	5mg	QQ客服：1413575084
恩镰孢菌素B; Enniatin B	CFN97902	917-13-5	C₃₃H₅₇N₃O₉ = 639.8	5mg	QQ客服：1413575084
恩镰孢菌素B1; Enniatin B1	CFN97986	19914-20-6	C₃₄H₅₉N₃O₉ = 653.9	5mg	QQ客服：2056216494
脱镁叶绿酸A甲酯; Methylpheophorbide A	CFN91976	5594-30-9	C₃₆H₃₈N₄O₅ = 606.71	5mg	QQ客服：3257982914
细胞松驰素D; Cytochalasin D	CFN98204	22144-77-0	C₃₀H₃₇NO₆ = 507.6	5mg	QQ客服：1457312923
细胞松驰素 C; Cytochalasin C	CFN70315	22144-76-9	C₃₀H₃₇NO₆ = 507.6	5mg	QQ客服：215959384
细胞松弛素B; Cytochalasin B	CFN96781	14930-96-2	C₂₉H₃₇NO₅ = 479.61	5mg	QQ客服：2056216494

信息支持

公司简介
订购流程
付款方式
退换货政策

ChemFaces提供的产品仅用于科学研究使用，不用于诊断或治疗程序。

联系方式

电机：027-84237783
传真：027-84254680
在线QQ: 1413575084
E-Mail：manager@chemfaces.com

湖北省武汉沌口经济技术开区车城南路83号1号楼第三层厂房

ChemFaces为科学家，科研人员与企业提供快速的产品递送。我们通过瑞士SGS ISO 9001:2008质量体系认证天然化合物与对照品的研发和生产。

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.6482 mL	8.2412 mL	16.4823 mL	32.9647 mL	41.2058 mL
5 mM	0.3296 mL	1.6482 mL	3.2965 mL	6.5929 mL	8.2412 mL
10 mM	0.1648 mL	0.8241 mL	1.6482 mL	3.2965 mL	4.1206 mL
50 mM	0.033 mL	0.1648 mL	0.3296 mL	0.6593 mL	0.8241 mL
100 mM	0.0165 mL	0.0824 mL	0.1648 mL	0.3296 mL	0.4121 mL