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  • 芥子酸甲酯

    • 芥子酸甲酯

    Methyl sinapate

    芥子酸甲酯
    		产品编号 CFN97787
    CAS编号 20733-94-2
    分子式 = 分子量 C12H14O5 = 238.24
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Phenylpropanoids
    植物来源 The herbs of Rauvolfia tetraphylla
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    芥子酸甲酯 CFN97787 20733-94-2 10mg QQ客服：1413575084
    芥子酸甲酯 CFN97787 20733-94-2 20mg QQ客服：1413575084
    芥子酸甲酯 CFN97787 20733-94-2 50mg QQ客服：1413575084
    芥子酸甲酯 CFN97787 20733-94-2 100mg QQ客服：1413575084
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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    • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Nat Commun.2024, 15(1):8221.
  • Biomolecules.2024, 14(10):1257.
  • Iranian J. Pharm. Res.2021, 20(4):59-70
  • Cell J.2024, 26(8):496-504.
  • Molecules.2023, 28(10):4062.
  • Int J Mol Sci. 2014, 15(5):8443-57
  • Preprints2021, doi:10.20944
  • Korean J. Crop Sci.2018, 63(2):131-139
  • Malaysian Journal of Analytical Sciences2022, 26(2):360-369.
  • Plants (Basel).2021, 10(5):951.
  • J Chromatogr B Analyt Technol Biomed Life Sci.2019, 1126-1127:121743
  • Phytother Res.2020, 34(4):788-795.
  • Antioxidants2022, 11(2),234.
  • Int J Mol Sci.2022, 23(1):538.
  • J Agric Food Chem.2024, 72(40):22237-22249.
  • Clin Exp Pharmacol Physiol.2015, 42(11):1189-97
  • Molecules.2016, 21(6)
  • Food Science&Tech. Res.2022, 28(2):123-132.
  • Anticancer Res.2021, 41(3):1357-1364.
  • Int J Mol Sci.2020, 21(8):2790.
  • Kyung Hee University2024, 4789969.
  • Phytomedicine.2017, 24:77-86
  • Oncol Rep.2021, 46(1):143.
  • ...
    • 生物活性
    Description: Methyl sinapate can increase the frequency of cells with chromosome aberrations in the CHO K-1 cells treated with MMC, 4NQO or UV.
    In vitro:
    Mutat Res. 1989 Jun;212(2):213-21.
    Enhancing effects of cinoxate and methyl sinapate on the frequencies of sister-chromatid exchanges and chromosome aberrations in cultured mammalian cells.[Pubmed: 2499777]

    METHODS AND RESULTS:
    Sister-chromatid exchanges (SCEs) induced by mitomycin C (MMC), 4-nitroquinoline-1-oxide (4NQO) or UV-light in cultured Chinese hamster ovary cells (CHO K-1 cells) were enhanced by cinoxate (2-ethoxyethyl p-methoxycinnamate) or Methyl sinapate (methyl 3,5-dimethoxy 4-hydroxycinnamate). Both substances are cinnamate derivatives and cinoxate is commonly used as a cosmetic UV absorber. Methyl sinapate also increased the frequency of cells with chromosome aberrations in the CHO K-1 cells treated with MMC, 4NQO or UV. These increasing effects of Methyl sinapate were critical in the G1 phase of the cell cycle and the decline of the frequencies of UV-induced SCEs and chromosome aberrations during liquid holding was not seen in the presence of Methyl sinapate. Both compounds were, however, ineffective in cells treated with X-rays. In cells from a normal human embryo and from a xeroderma pigmentosum (XP) patient, MMC-induced SCEs were also increased by the post-treatment with Methyl sinapate. The SCE frequencies in UV-irradiated normal human cells were elevated by Methyl sinapate, but no SCE-enhancing effects were observed in UV-irradiated XP cells.
    CONCLUSIONS:
    Our results suggest that the test substances inhibit DNA excision repair and that the increase in the amount of unrepaired DNA damage might cause the enhancement of induced SCEs and chromosome aberrations.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.1974 mL 20.9872 mL 41.9745 mL 83.949 mL 104.9362 mL
    5 mM 0.8395 mL 4.1974 mL 8.3949 mL 16.7898 mL 20.9872 mL
    10 mM 0.4197 mL 2.0987 mL 4.1974 mL 8.3949 mL 10.4936 mL
    50 mM 0.0839 mL 0.4197 mL 0.8395 mL 1.679 mL 2.0987 mL
    100 mM 0.042 mL 0.2099 mL 0.4197 mL 0.8395 mL 1.0494 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    反式-5-羟基阿魏酸; trans-5-Hydroxyferulic acid CFN70250 110642-42-7 C10H10O5 = 210.2 5mg QQ客服：2159513211
    芥子醇; Sinapyl alcohol CFN91507 537-33-7 C11H14O4 = 210.2 20mg QQ客服：1457312923
    反-3,5-二甲氧基-4-羟基肉桂醛; trans-3,5-Dimethoxy-4-hydroxy cinnamaldehyde CFN70106 4206-58-0 C11H12O4 = 208.2 20mg QQ客服：2056216494
    3,5-二甲氧基-4-羟基肉桂酸，芥子酸; Sinapic acid CFN92631 530-59-6 C11H12O5 = 224.2 20mg QQ客服：2159513211
    芥子酸甲酯; Methyl sinapate CFN97787 20733-94-2 C12H14O5 = 238.24 20mg QQ客服：3257982914
    3,4,5-三甲氧基肉桂酸; 3,4,5-Trimethoxy-trans-cinnamic acid CFN92506 20329-98-0 C12H14O5 = 238.2 20mg QQ客服：1413575084
    3,4,5-三甲氧基肉桂酸; 3,4,5-Trimethoxycinnamic acid CFN98182 90-50-6 C12H14O5 = 238.24 20mg QQ客服：2159513211
    3,4,5-三甲基肉桂酸甲酯; Methyl 3,4,5-trimethoxycinnamate CFN97691 7560-49-8 C13H16O5 = 252.26 20mg QQ客服：2056216494
    2,3,4-三甲氧基肉桂酸; trans-2,3,4-Trimethoxycinnamic acid CFN98189 33130-03-9 C12H14O5 = 238.24 20mg QQ客服：2159513211
    Secodihydro-hydramicromelin B; Secodihydro-hydramicromelin B CFN97911 1212148-58-7 C15H18O8 = 326.3 5mg QQ客服：1457312923

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