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  • 氯化锦葵色素

    Malvidin chloride

    氯化锦葵色素
    产品编号 CFN92035
    CAS编号 643-84-5
    分子式 = 分子量 C17H15ClO7 = 366.8
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Flavonoids
    植物来源 The fruits of Vaccinium myrtillus
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    氯化锦葵色素 CFN92035 643-84-5 1mg QQ客服:2056216494
    氯化锦葵色素 CFN92035 643-84-5 5mg QQ客服:2056216494
    氯化锦葵色素 CFN92035 643-84-5 10mg QQ客服:2056216494
    氯化锦葵色素 CFN92035 643-84-5 20mg QQ客服:2056216494
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Uniwersytet Medyczny w ?odzi (Poland)
  • Julius Kühn-Institut (Germany)
  • Centrum Menselijke Erfelijkheid (Belgium)
  • Nicolaus Copernicus Uniwersity (Poland)
  • Instituto de Investigaciones Agropecuarias (Chile)
  • Amity University (India)
  • Lodz University of Technology (Poland)
  • University of Minnesota (USA)
  • Osmania University (India)
  • Korea Food Research Institute(KFRI) (Korea)
  • University of British Columbia (Canada)
  • Ain Shams University (Egypt)
  • University of East Anglia (United Kingdom)
  • Korea Intitute of Science and Technology (KIST) (Korea)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Food Chemistry: X.2022, 2022.100270
  • Mol Med Rep.2024, 29(2):26.
  • Plant Growth Regulation2020, 90(2):383-392
  • Phytochem Anal.2016, 27(5):296-303
  • Food Res Int.2018, 106:909-919
  • Journal of Apiculture2019, 34(2):131-136
  • Antioxidants (Basel).2020, 9(6):526.
  • Biomedicine & Pharmacotherapy2022, 153:113404.
  • Evid-Based Compl Alt2020, 7202519:13
  • Plants (Basel).2023, 12(22):3877.
  • Antioxidants (Basel).2023, 12(1):189.
  • Environ Toxicol.2023, 38(5):1174-1184.
  • Food Science and Human Wellness2022, 11(4):965-974
  • Front Microbiol.2023, 14:921653.
  • FUTURE VIROLOGYVOL.2023, 18(5).
  • J Chromatogr B Analyt Technol Biomed Life Sci.2020, 1149:122123.
  • Theranostics.2023, 13(9):3103-3116.
  • Front Nutr.2021, 8: 687851.
  • Phytomedicine.2019, 58:152893
  • Environ Toxicol.2019, 34(12):1354-1362
  • Molecules.2019, 24(11):E2102
  • Environ Toxicol.2024, 39(3):1556-1566.
  • Plant Pathology2022, 13527
  • ...
  • 生物活性
    Description: Malvidin chloride has anti-spermatogenic, and antioxidant activities. It can prevent endothelial dysfunction by inhibiting ROS and XO-1.
    Targets: ROS | XO-1
    In vitro:
    Food Science, 2015.
    Antioxidant Effect of Blueberry Malvidin Chloride in Human Umbilical Vein Endothelial Cells.[Reference: WebLink]
    The effect of malvidin chloride(Mv-Cl) extracted from blueberries on the amounts of reactive oxygen species(ROS) and xanthine oxidase-1(XO-1) in human umbilical vein endothelial cells(HUVECs) was investigated to explore the antioxidant potential of the anthocyanin compound.
    METHODS AND RESULTS:
    HUVECs were in vitro cultured in the presence of Mv-Cl(1, 5 and 10 μmol/L), angiotensinⅡ(Ang II, 10-2 μmol/L) and their combination, respectively. DMSO was used as control. The ROS content in the cells was detected by immunofluorescence. The soluble XO-1 protein content in the cell culture supernatant was detected by ELISA. The protein expression of XO-1 in the cells was assessed by Western blotting. The content of ROS and the protein expression of XO-1 in HUVECs were decreased when treated with low concentration of Mv-Cl. Ang II significantly increased ROS and XO-1 content, and Mv-Cl appeared to specifically down-regulate the production of ROS and XO-1.
    CONCLUSIONS:
    Malvidin chloride can prevent endothelial dysfunction by inhibiting ROS and XO-1. Therefore, blueberry anthocyanin may be a new inhibitor of ROS and XO-1, which provides a theoretical basis for the application of blueberry anthocyanins to prevent cardiovascular diseases as a functional food or nutraceutical ingredient.
    Nutrition and Cancer, 2011, 63(7):1044-1052.
    Inhibitory Effect of Antioxidant Extracts From Various Potatoes on the Proliferation of Human Colon and Liver Cancer Cells.[Reference: WebLink]
    Antioxidant extracts from 5 potato lines were evaluated for antioxidant activity, total phenolics, chlorogenic acid, anthocyanin content, and in vitro anticancer capacity.
    METHODS AND RESULTS:
    Analysis showed that Mexican wild species S. pinnatisectum had the highest antioxidant activity, total phenolic, and chlorogenic acid content. The proliferation of colon cancer and liver cancer cells was significantly inhibited by potato antioxidant extracts. The highest antiproliferative activity was observed in extracts of S. pinnatisectum and the lowest in Northstar. An inverse correlation was found between total phenolics and the EC50 of colon cancer cell (R2 = 0.9303), as well as liver cancer cell proliferation (R2 = 0.8992). The relationship between antioxidant activity and EC50 of colon cancer/liver cancer cell proliferation was significant (R2 = 0.8144; R2 = 0.956, respectively).
    CONCLUSIONS:
    A significant difference in inhibition of cancer cells (P < 0.01) existed between the 3 polyphenols: chlorogenic acid, pelargonidin chloride, and malvidin chloride, suggesting that chlorogenic acid was a critical factor in the antiproliferation of colon cancer and liver cancer cells.
    In vivo:
    International Journal of Andrology, 1990, 13(3):207-215.
    Anti-spermatogenic activity of malvidin chloride in langur monkeys (Presbytis entellus entellus Dufresne).[Reference: WebLink]
    Malvidin chloride (MC) a colouring agent from flowers of Malvaviscus conzattii Greenum was studied for male anti-fertility effects in adult langur monkeys (Presbytis entellus entellus Dufresne).
    METHODS AND RESULTS:
    When fed 50 mg MC kg-1 for a period of 60 days, inhibition of spermatogenesis resulted. The weights of testes and epididymides were reduced and there was atrophy of the Leydig cells. In the epididymis, epithelial cell heights were reduced after MC-treatment. Conspicuous shrinkage of seminiferous tubules and Leydig cell nuclei were evident. Depletion of total proteins, RNA, sialic acid, alkaline/acid phosphatase activity in testes and epididymides with the elevation of testicular levels of cholesterol and glycogen also occurred. Blood/serum analysis and haematology of MC-treated langur monkeys revealed that all of the clinically important parameters were well within the normal range. The slightly increased bilirubin concentration and alkaline phosphatase activity returned to normal range within 30 days of the last dose of MC. The anti-spermatogenic activity of MC in langur monkeys is discussed.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.7263 mL 13.6314 mL 27.2628 mL 54.5256 mL 68.157 mL
    5 mM 0.5453 mL 2.7263 mL 5.4526 mL 10.9051 mL 13.6314 mL
    10 mM 0.2726 mL 1.3631 mL 2.7263 mL 5.4526 mL 6.8157 mL
    50 mM 0.0545 mL 0.2726 mL 0.5453 mL 1.0905 mL 1.3631 mL
    100 mM 0.0273 mL 0.1363 mL 0.2726 mL 0.5453 mL 0.6816 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    氯化矢车菊素-3-O-槐糖苷; Cyanidin 3-sophoroside chloride CFN90469 18376-31-3 C27H31O16.Cl = 646.99 5mg QQ客服:1457312923
    氯化矢车菊素-3-O-(6''-丙二酰葡糖苷); Cyanidin-3-O-(6''-malonylglucoside) chloride CFN91864 171828-62-9 C24H23ClO14 = 570.9 5mg QQ客服:3257982914
    氯化锦葵色素; Malvidin chloride CFN92035 643-84-5 C17H15ClO7 = 366.8 10mg QQ客服:2159513211
    氯化锦葵色素-3-O-阿拉伯糖苷; Malvidin-3-O-arabinoside chloride CFN92050 28500-04-1 C22H23ClO11 = 498.9 5mg QQ客服:3257982914
    氯化锦葵色素-3-O-葡萄糖苷; Malvidin-3-O-glucoside chloride CFN92049 7228-78-6 C23H25ClO12 = 528.9 10mg QQ客服:2159513211
    氯化锦葵色素-3-O-半乳糖苷; Malvidin-3-O-galactoside chloride CFN92048 30113-37-2 C23H25ClO12 = 528.9 10mg QQ客服:2159513211
    氯化锦葵色素-3,5-O-双葡萄糖苷; Malvidin-3,5-O-diglucoside chloride CFN91867 16727-30-3 C29H35ClO17 = 691.0 10mg QQ客服:1457312923
    氯化矮牵牛素; Petunidin chloride CFN92036 1429-30-7 C16H13ClO7 = 352.7 5mg QQ客服:215959384
    氯化矮牵牛素-3-O-葡萄糖苷; Petunidin-3-O-glucoside chloride CFN92043 6988-81-4 C22H23ClO12 = 514.9 5mg QQ客服:2056216494
    氯化矮牵牛素-3-O-半乳糖苷; Petunidin-3-O-galactoside chloride CFN92042 28500-02-9 C22H23ClO12 = 514.9 5mg QQ客服:1413575084

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