异肥皂草苷
Isosaponarin
|
|
产品编号 |
CFN90133 |
| CAS编号 |
19416-87-6 |
| 分子式 = 分子量 |
C27H30O15 = 594.52 |
| 产品纯度 |
>=98% |
| 物理属性 |
Yellow powder |
| 化合物类型 |
Flavonoids |
| 植物来源 |
The seeds of Vaccaria segetalis |
| ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用 |
|
| 产品名称 |
产品编号 |
CAS编号 |
包装 |
QQ客服 |
| 异肥皂草苷 |
CFN90133 |
19416-87-6 |
1mg |
QQ客服：3004468091 |
| 异肥皂草苷 |
CFN90133 |
19416-87-6 |
5mg |
QQ客服：3004468091 |
| 异肥皂草苷 |
CFN90133 |
19416-87-6 |
10mg |
QQ客服：3004468091 |
| 异肥皂草苷 |
CFN90133 |
19416-87-6 |
20mg |
QQ客服：3004468091 |
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ChemFaces的产品在许多优秀和顶级科学期刊中被引用
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
我们的产品现已经出口到下面的研究机构与大学，并且还在增涨
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University of Medicine and Pharmacy (Romania)
Center for protein Engineering (CIP) (Belgium)
Johannes Gutenberg University Mainz (JGU) (Germany)
Anna University (India)
Institute of Bioorganic Chemistry Polish Academy of Sciences (Poland)
University of Cincinnati (USA)
MTT Agrifood Research Finland (Finland)
Universitas islam negeri Jakarta (Indonesia)
VIB Department of Plant Systems Biology, UGent (PSB) (Belgium)
Calcutta University (India)
Universidade Federal de Pernambuco (UFPE) (Brazil)
The Institute of Cancer Research (United Kingdom)
Leibniz-Institut für Pflanzenbiochemie (IPB) (Germany)
More...
国外学术期刊发表的引用ChemFaces产品的部分文献
| Description: |
Isosaponarin increases collagen synthesis in human fibroblasts, causes by up-regulated TbetaR-II and P4H production. |
| Targets: |
TGF-β/Smad |
| In vitro: |
| J Nat Med. 2010 Jul;64(3):305-12. | | The effect of isosaponarin isolated from wasabi leaf on collagen synthesis in human fibroblasts and its underlying mechanism.[Pubmed: 20349148 ] | Wasabi has been used as an important spice in Japanese foods. The wasabi leaves were used as a cosmetic material, but its biological activities have not yet been examined.
METHODS AND RESULTS:
We investigated the effect of Isosaponarin derived from wasabi leaf on collagen synthesis in human fibroblasts. The production of type I collagen in human fibroblasts was increased with treatment of wasabi leaf extract. Isosaponarin isolated from wasabi leaves belonged to the group of flavone glycoside, and was the key compound in collagen synthesis from the wasabi leaf ingredients. Isosaponarin increased the type I collagen production at the mRNA gene level. The treatment of Isosaponarin did not influence the production of transforming growth factor-beta (TGF-beta) protein, but increased the production of TGF-beta type II receptor (TbetaR-II) protein and TbetaR-II mRNA. Prolyl 4-hydroxylase (P4H) protein and P4H mRNA were increased by treatment with Isosaponarin. Heat shock protein 47 (HSP47) was not increased by treatment with Isosaponarin.
CONCLUSIONS:
These results suggested that Isosaponarin increased collagen synthesis in human fibroblasts, caused by up-regulated TbetaR-II and P4H production. |
|
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
1.682 mL |
8.4101 mL |
16.8203 mL |
33.6406 mL |
42.0507 mL |
| 5 mM |
0.3364 mL |
1.682 mL |
3.3641 mL |
6.7281 mL |
8.4101 mL |
| 10 mM |
0.1682 mL |
0.841 mL |
1.682 mL |
3.3641 mL |
4.2051 mL |
| 50 mM |
0.0336 mL |
0.1682 mL |
0.3364 mL |
0.6728 mL |
0.841 mL |
| 100 mM |
0.0168 mL |
0.0841 mL |
0.1682 mL |
0.3364 mL |
0.4205 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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