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  • 鸢尾酚酮3-C-beta-D-吡喃葡萄糖苷

    Iriflophenone 3-C-beta-D-glucopyranoside

    鸢尾酚酮3-C-beta-D-吡喃葡萄糖苷
    产品编号 CFN99063
    CAS编号 104669-02-5
    分子式 = 分子量 C19H20O10 = 408.4
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Xanthones
    植物来源 The herbs of Aquilaria sinensis
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    鸢尾酚酮3-C-beta-D-吡喃葡萄糖苷 CFN99063 104669-02-5 1mg QQ客服:2159513211
    鸢尾酚酮3-C-beta-D-吡喃葡萄糖苷 CFN99063 104669-02-5 5mg QQ客服:2159513211
    鸢尾酚酮3-C-beta-D-吡喃葡萄糖苷 CFN99063 104669-02-5 10mg QQ客服:2159513211
    鸢尾酚酮3-C-beta-D-吡喃葡萄糖苷 CFN99063 104669-02-5 20mg QQ客服:2159513211
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

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    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • University of Burgos2024, ssrn.4795441.
  • Plants.2024, 13(10):1348;
  • J Formos Med Assoc.2020, S0929-6646(20)30425-3
  • J Pharm Biomed Anal2016, 118:183-194
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  • Molecules.2021, 26(6):1635.
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  • ...
  • 生物活性
    Description: Iriflophenone-3-C-β-d-glucoside shows potent inhibitory activity against α-glucosidase. Iriflophenone 3-C-β-D-glucoside and mangiferin which along with 3 β taraxerol and other sterols could be contributing to the cholesterol lowering activity. Iriflophenone-3- C -glucoside has antioxidant activity, it presents no radical scavenging ability against DPPH , but scavenges ABTS + and peroxyl radicals (TEAC ABTS of 1.04 and TEAC ORAC of 3.61).
    In vitro:
    J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Mar 1;951-952:164-71.
    Iriflophenone-3-C-glucoside from Cyclopia genistoides: isolation and quantitative comparison of antioxidant capacity with mangiferin and isomangiferin using on-line HPLC antioxidant assays.[Pubmed: 24566268 ]

    METHODS AND RESULTS:
    The benzophenone, iriflophenone-3-C-glucoside, was isolated from Cyclopia genistoides using a combination of fluid-fluid extraction, high performance counter-current chromatography (HPCCC) and semi-preparative high performance liquid chromatography (HPLC). The microplate oxygen radical absorbance capacity (ORAC) assay, with fluorescein as probe, was adapted for use in an on-line HPLC configuration. The method was validated using a mixture of authentic standards including iriflophenone-3-C-glucoside(Iriflophenone 3-C-beta-D-glucopyranoside), and the xanthones, mangiferin and isomangiferin. Trolox (6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid) was included in the mixture for calculation of Trolox equivalent antioxidant capacity (TEAC) values. Using the on-line HPLC-ORAC assay, as well as 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS(+)) on-line assays, the antioxidant activity of iriflophenone-3-C-glucoside(Iriflophenone 3-C-beta-D-glucopyranoside) and isomangiferin was demonstrated for the first time.
    CONCLUSIONS:
    Iriflophenone-3-C-glucoside(Iriflophenone 3-C-beta-D-glucopyranoside) presented no radical scavenging ability against DPPH, but scavenged ABTS(+) and peroxyl radicals (TEACABTS of 1.04 and TEACORAC of 3.61). Isomangiferin showed slightly lower antioxidant capacity than mangiferin against DPPH (TEACDPPH of 0.57 vs. 0.62), but higher capacity against ABTS(+) (TEACABTS of 1.82 vs. 1.67) and peroxyl radical (TEACORAC of 4.14 vs. 3.69) than mangiferin. The on-line HPLC-ORAC assay was shown to be more sensitive for radical scavengers, but at the same time less selective for rapid radical scavengers than the DPPH assay.
    In vivo:
    Pharmacognosy Res. 2017 Jan-Mar;9(1):21-26.
    Evaluation of Cholesterol-lowering Activity of Standardized Extract of Mangifera indica in Albino Wistar Rats.[Pubmed: 28250649 ]
    Cholesterol lowering activity of Mangifera indica L. has been determined by earlier researchers and kernel, leaf and bark have shown significant activity. However, the specific cholesterol lowering activity of leaf methanol extract has not been determined.
    METHODS AND RESULTS:
    The present study involved evaluation of cholesterol lowering potential of methanol extract of M. indica leaves using high cholesterol diet model in albino Wistar rats. The acute oral toxicity at a dose of 5000 mg/ kg body weight was also determined in female albino Wistar rats. Phytoconstituents Iriflophenone 3-C-beta-D-glucopyranoside and mangiferin were quantified in methanol extracts of different varieties of mango leaves using high performance liquid chromatography. Significant cholesterol lowering activity was observed with methanol extract of M. indica leaves, at dose of 90 mg/kg body weight in rats and it was also found to be safe at dose of 5000 mg/kg rat body. Iriflophenone 3-C-beta-D-glucopyranoside and mangiferin were found to be in the range of 1.2 to 2.8% w/w and 3.9 to 4.6% w/w, respectively which along with 3 β taraxerol and other sterols could be contributing to the cholesterol lowering activity of mango leaves extract.
    CONCLUSIONS:
    The phytosterols rich extract of Mangifera indica leaves is a good source of nutraceutical ingredient that have the potential to lower serum cholesterol levels.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.4486 mL 12.2429 mL 24.4858 mL 48.9716 mL 61.2145 mL
    5 mM 0.4897 mL 2.4486 mL 4.8972 mL 9.7943 mL 12.2429 mL
    10 mM 0.2449 mL 1.2243 mL 2.4486 mL 4.8972 mL 6.1214 mL
    50 mM 0.049 mL 0.2449 mL 0.4897 mL 0.9794 mL 1.2243 mL
    100 mM 0.0245 mL 0.1224 mL 0.2449 mL 0.4897 mL 0.6121 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    鸢尾酚酮3-C-beta-D-吡喃葡萄糖苷; Iriflophenone 3-C-beta-D-glucopyranoside CFN99063 104669-02-5 C19H20O10 = 408.4 5 mg QQ客服:2056216494
    硫赭曲菌素; Sulochrin CFN96651 519-57-3 C17H16O7 = 332.30 5mg QQ客服:2056216494
    Monomethylsulochrin ; Monomethylsulochrin CFN96952 10056-14-1 C18H18O7 = 346.33 5mg QQ客服:2056216494
    9-Dehydroxyeurotinone; 9-Dehydroxyeurotinone CFN89103 1360606-85-4 C15H12O5 = 272.25 5mg QQ客服:3257982914
    (2,3-二羟基苯基)(2-羟基-4,6-二甲氧基苯基)甲酮; 2,2',3'-Trihydroxy-4,6-dimethoxybenzophenone CFN98091 219861-73-1 C15H14O6 = 290.3 5mg QQ客服:1413575084
    2,3',4,6-四羟基二苯甲酮; 2,3',4,6-Tetrahydroxybenzophenone CFN98302 26271-33-0 C13H10O5 = 246.2 5mg QQ客服:1413575084
    柯托苷; 2,6-二羟基-4-甲氧基二苯甲酮; Cotoin CFN98729 479-21-0 C14H12O4 = 244.2 10mg QQ客服:3257982914
    2,5-二羟基-4-甲氧基二苯甲酮; Cearoin CFN89497 52811-37-7 C14H12O4 = 244.24 5mg QQ客服:1413575084
    2,6,4’-三羟基-4-甲氧基二苯甲酮; 2,6,4'-Trihydroxy-4-methoxybenzophenone CFN89307 55051-85-9 C14H12O5 = 260.24 10mg QQ客服:2056216494
    桑橙素,2,3',4,4',6-五羟基二苯甲酮; Maclurin CFN98836 519-34-6 C13H10O6 = 262.2 5mg QQ客服:3257982914

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