绣球酚

Hydrangenol

	产品编号	CFN98745
	CAS编号	480-47-7
	分子式 = 分子量	C₁₅H₁₂O₄ = 256.3
	产品纯度	>=98%
	物理属性	Powder
	化合物类型	Flavonoids
	植物来源	The herbs of Hydrangea hortensia
ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用

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产品名称	产品编号	CAS编号	包装	QQ客服
绣球酚	CFN98745	480-47-7	1mg	QQ客服：1457312923
绣球酚	CFN98745	480-47-7	5mg	QQ客服：1457312923
绣球酚	CFN98745	480-47-7	10mg	QQ客服：1457312923
绣球酚	CFN98745	480-47-7	20mg	QQ客服：1457312923

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ChemFaces的产品在许多优秀和顶级科学期刊中被引用

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089

Universidade de Franca (Brazil)

University of Minnesota (USA)

John Innes Centre (United Kingdom)

Yale University (USA)

Seoul National University (Korea)

St. Jude Children Research Hospital (USA)

Calcutta University (India)

Almansora University (Egypt)

Northeast Normal University Changchun (China)

Institute of Bioorganic Chemistry Polish Academy of Sciences (Poland)

University of South Australia (Australia)

Research Unit Molecular Epigenetics (MEG) (Germany)

S.N.D.T. Women's University (India)

University of Hertfordshire (United Kingdom)

More...

Description:

Hydrangenol is a strong contact sensitizer found in hydrangea (Hydrangea sp.; Hydrangeaceae), it can significantly inhibit the passive cutaneous anaphylaxis (PCA) reaction, it has antiallergic activity. Hydrangenol has anti-inflammatory, and antifungal activities,it can attenuate NO production and inducible NO synthase expression in lipopolysaccharide (LPS)-stimulated BV2 microglial cells by inhibiting NF-κB activation and by stimulating the Nrf2-mediated HO-1 signaling pathway. Hydrangenol has antifungal activity.

Targets:

NO | NOS | NF-kB | HO-1 | Nrf2 | Antifection

In vitro:

Biol Pharm Bull. 1999 Aug;22(8):870-2.

Effects of phyllodulcin, hydrangenol, and their 8-O-glucosides, and thunberginols A and F from Hydrangea macrophylla SERINGE var. thunbergii MAKINO on passive cutaneous anaphylaxis reaction in rats.[Pubmed: 10480329]

METHODS AND RESULTS:
We examined the antiallergic effects of phyllodulcin, hydrangenol, and their 8-O-glucosides, and thunberginols A and F isolated from the processed leaves (Hydrangeae Dulcis Folium) and dried leaves of Hydrangea macrophylla SERINGE var. thunbergii MAKINO using the passive cutaneous anaphylaxis (PCA) reaction. With the exception of phyllodulcin, these constituents were found to significantly inhibit the PCA reaction.
CONCLUSIONS:
Although thunberginol A showed the most potent inhibitory effect, hydrangenol was considered to be the principal antiallergic component in the processed leaves, after taking into account their contents.

Chem Pharm Bull (Tokyo). 1981 Sep;29(9):2689-91.

Antifungal activity of oosponol, oospolactone, phyllodulcin, hydrangenol, and some other related compounds.[Pubmed: 7349286]

METHODS AND RESULTS:
Antifungal activity of oosponol, oospolactone, phyllodulcin, hydrangenol, and some other related compounds.

Contact Dermatitis. 1991 Mar;24(3):233-5.

Hydrangenol, a strong contact sensitizer found in hydrangea (Hydrangea sp.; Hydrangeaceae).[Pubmed: 1868712]

METHODS AND RESULTS:
Hydrangenol, a strong contact sensitizer found in hydrangea (Hydrangea sp.; Hydrangeaceae).

产品名称	产品编号	CAS编号	分子式 = 分子量	位单	联系QQ
绣球酚; Hydrangenol	CFN98745	480-47-7	C₁₅H₁₂O₄ = 256.3	5mg	QQ客服：2159513211
绣球酚8-O-葡萄糖甙; Hydrangenol 8-O-glucoside	CFN97153	67600-94-6	C₂₁H₂₂O₉ = 418.4	5mg	QQ客服：1413575084
(3R)-绣球酚8-O-葡萄糖甙五乙酸酯; (3R)-Hydrangenol 8-O-glucoside pentaacetate	CFN99230	113270-98-7	C₃₁H₃₂O₁₄ = 628.6	5mg	QQ客服：1413575084
(3S)-绣球酚8-O-葡萄糖甙五乙酸酯; (3S)-Hydrangenol 8-O-glucoside pentaacetate	CFN99231	113270-99-8	C₃₁H₃₂O₁₄ = 628.6	5mg	QQ客服：2056216494
Thunberginol C; Thunberginol C	CFN99610	147517-06-4	C₁₅H₁₂O₅ = 272.3	5mg	QQ客服：2056216494
仙鹤草内酯; Agrimonolide	CFN98073	21499-24-1	C₁₈H₁₈O₅ = 314.3	5mg	QQ客服：3257982914
仙鹤草内酯-6-O-葡萄糖甙; Agrimonolide 6-O-glucoside	CFN99374	126223-29-8	C₂₄H₂₈O₁₀ = 476.5	5mg	QQ客服：215959384
5,6-Desmethylenedioxy-5-methoxyaglalactone; 5,6-Desmethylenedioxy-5-methoxyaglalactone	CFN89361	922169-96-8	C₁₇H₁₆O₅ = 300.30	5mg	QQ客服：2056216494
6,8-Di-O-methylcitreoisocoumarin; 6,8-Di-O-methylcitreoisocoumarin	CFN89086	908098-80-6	C₁₆H₁₈O₆ = 306.31	5mg	QQ客服：1457312923

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	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.9017 mL	19.5084 mL	39.0168 mL	78.0336 mL	97.5419 mL
5 mM	0.7803 mL	3.9017 mL	7.8034 mL	15.6067 mL	19.5084 mL
10 mM	0.3902 mL	1.9508 mL	3.9017 mL	7.8034 mL	9.7542 mL
50 mM	0.078 mL	0.3902 mL	0.7803 mL	1.5607 mL	1.9508 mL
100 mM	0.039 mL	0.1951 mL	0.3902 mL	0.7803 mL	0.9754 mL