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  • 人参皂苷Ra1

    Ginsenoside Ra1

    人参皂苷Ra1
    产品编号 CFN93292
    CAS编号 83459-41-0
    分子式 = 分子量 C58H98O26 = 1211.39
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Triterpenoids
    植物来源 The roots of Panax ginseng C. A. Mey.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    人参皂苷Ra1 CFN93292 83459-41-0 1mg QQ客服:2056216494
    人参皂苷Ra1 CFN93292 83459-41-0 5mg QQ客服:2056216494
    人参皂苷Ra1 CFN93292 83459-41-0 10mg QQ客服:2056216494
    人参皂苷Ra1 CFN93292 83459-41-0 20mg QQ客服:2056216494
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Chang Gung University (Taiwan)
  • Research Unit Molecular Epigenetics (MEG) (Germany)
  • Sapienza University of Rome (Italy)
  • Osmania University (India)
  • Rio de Janeiro State University (Brazil)
  • Universidade de Franca (Brazil)
  • John Innes Centre (United Kingdom)
  • Instituto Politécnico de Bragan?a (Portugal)
  • University of Oslo (Norway)
  • Center for protein Engineering (CIP) (Belgium)
  • University of Minnesota (USA)
  • University of Malaya (Malaysia)
  • Chungnam National University (Korea)
  • The University of Newcastle (Australia)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Plant Cell Tiss Org2017, 479-486
  • Nat Commun.2023, 14(1):5075.
  • BioResources J.2020, 15(3).
  • Molecules.2021, 26(19):6032.
  • Nat Prod Sci.2018, 24(3):206
  • Sci Rep.2019, 9(1):4342
  • BioRxiv-The Preprint server for biology2023, 586957.
  • J Nat Prod.2021, 84(9):2544-2553.
  • Neurochem Int.2020, 133:104629
  • J Neuroinflammation.2020, 17(1):75.
  • Molecules.2021, 26(4):817.
  • Daru.2022, 30(2):273-288.
  • Food Res Int.2022, 157:111207.
  • Molecules.2023, 28(8):3503.
  • Food Chem.2021, 337:128023.
  • Food and Fermentation Industries2019, 45(7):45-51
  • Int. J. Mol. Sci.2022, 23(19), 11900.
  • Recent Pat Anticancer Drug Discov.2022, 17(4):416-426.
  • J Ethnopharmacol.2022, 289:115018.
  • Biochem Systematics and Ecology2017, 11-18
  • Int J Mol Sci.2018, 19(2)
  • Antioxidants (Basel).2023, 12(12):2078.
  • J Adv Res.2019, 17:85-94
  • ...
  • 生物活性
    Description: Ginsenoside Ra1 shows significant inhibitory effects on protein tyrosine kinase (PTK) activation induced by hypoxia/reoxygenation (H/R).
    In vitro:
    Planta Med. 2001 Feb;67(1):19-23.
    The inhibitory effects of ginsenosides on protein tyrosine kinase activated by hypoxia/reoxygenation in cultured human umbilical vein endothelial cells.[Pubmed: 11270715]

    METHODS AND RESULTS:
    27 individual ginsenosides and aglycones, together with five extracts from ginseng roots, ginseng leaves, American ginseng roots, American ginseng leaves and non-saponin fraction from roots of Panax ginseng, were tested for their effects on protein tyrosine kinase (PTK) activation induced by an in vitro hypoxia/reoxygenation (H/R) model in cultured human umbilical vein endothelial cells (HUVEC). The results indicated that ginsenoside Rb1 (3), ginsenoside Rd (7), Ginsenoside Ra1 (1) and ginsenoside Ro (27) showed significant inhibitory effects on PTK activation induced by H/R. Dose-response experiments revealed that ginsenoside-Rb1 was the most active compound and it completely blocked PTK activation at a wide range of concentrations.
    CONCLUSIONS:
    Most protopanaxadiol-type ginsenosides and some protopanaxatriol-type saponins also showed significant effects on PTK activation. However, the crude extracts did not protect against H/R-induced PTK activation.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 0.8255 mL 4.1275 mL 8.255 mL 16.51 mL 20.6374 mL
    5 mM 0.1651 mL 0.8255 mL 1.651 mL 3.302 mL 4.1275 mL
    10 mM 0.0825 mL 0.4127 mL 0.8255 mL 1.651 mL 2.0637 mL
    50 mM 0.0165 mL 0.0825 mL 0.1651 mL 0.3302 mL 0.4127 mL
    100 mM 0.0083 mL 0.0413 mL 0.0825 mL 0.1651 mL 0.2064 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    12-羟基灵芝酸D; 12-Hydroxyganoderic acid D CFN91921 942950-96-1 C30H42O8 = 530.65 5mg QQ客服:1413575084
    升麻酸B; Cimicifugic acid B CFN70303 205114-66-5 C21H20O11 = 448.4 5mg QQ客服:2056216494
    柽柳黄素; Tamarixetin CFN97027 603-61-2 C16H12O7 = 316.3 5mg QQ客服:215959384
    槲皮素3-O-(6''-没食子酰基)-β-D-半乳糖苷; Quercetin 3-O-(6''-galloyl)-beta-D-galactopyranoside CFN91065 53171-28-1 C28H24O16 = 616.5 10mg QQ客服:215959384

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