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  • Dorsmanin A

    Dorsmanin A

    Dorsmanin A
    产品编号 CFN96193
    CAS编号 162229-27-8
    分子式 = 分子量 C20H20O4 = 324.4
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Chalcones
    植物来源 The herbs of Psoralea corylifolia
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    Dorsmanin A CFN96193 162229-27-8 1mg QQ客服:215959384
    Dorsmanin A CFN96193 162229-27-8 5mg QQ客服:215959384
    Dorsmanin A CFN96193 162229-27-8 10mg QQ客服:215959384
    Dorsmanin A CFN96193 162229-27-8 20mg QQ客服:215959384
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Copenhagen University (Denmark)
  • Helmholtz Zentrum München (Germany)
  • Agricultural Research Organization (ARO) (Israel)
  • Institute of Pathophysiology Medical University of Vienna (Austria)
  • The Institute of Cancer Research (United Kingdom)
  • University of Dicle (Turkey)
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  • FORTH-IMBB (Greece)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • J Pharm Biomed Anal.2018, 151:32-41
  • J Plant Biotechnol.2023, 50:070-075.
  • Universidade Estadual Paulista2017, 11449
  • Molecules.2023, 28(13):4907.
  • New Journal of Chemistry2019, 43:12538-12547
  • Phytochem Anal.2023, pca.3305.
  • Front Plant Sci.2020, 11:630.
  • Sci Rep.2019, 9(1):4646
  • Molecules.2019, 24(2):329
  • Anticancer Agents Med Chem.2023, 23(10):1204-1210.
  • iScience.2023, 26(9):107602.
  • Nutr Res Pract2019, 13:e45
  • Molecules2022, 27(9):2992.
  • Buildings2023, 13(5), 1112.
  • Translational Neuroscience2024, 15:20220339
  • J Nat Med.2017, 71(2):457-462
  • Cancers (Basel).2021, 13(17):4327.
  • Metabolites. 2023, 13(11):1122.
  • Scientific World Journal.2014, 2014:654193
  • J Am Soc Mass Spectrom.2021, 32(5):1205-1214.
  • Plant Physiol.2024, 194(4):2580-2599.
  • J Chromatogr B Analyt Technol Biomed Life Sci.2019, 1126-1127:121743
  • Chin J Appl. Physiol.2019, 35(3):283-288
  • ...
  • 生物活性
    Description: Dorsmanin A is a natural product from Psoralea corylifolia.
    In vitro:
    BMC Complement Altern Med. 2012 Jun 29;12:83.
    Antimicrobial activities of the methanol extract and compounds from the twigs of Dorstenia mannii (Moraceae).[Pubmed: 22747736 ]
    Dorstenia mannii (Moraceae) is a medicinal herb used traditionally for the treatment of many diseases. In the present study, the methanol extract of D. mannii and nine of its isolated compounds, namely Dorsmanin A (1), B (2), C (3), D (4), E (6), F (7), G (8) dorsmanin I (9) and 6,8-diprenyleriodictyol (5), were tested for their antimicrobial activities against yeast, Mycobacteria and Gram-negative bacteria.
    METHODS AND RESULTS:
    The microplate alamar blue assay (MABA) and the broth microdilution method were used to determine the minimal inhibitory concentration (MIC) and minimal microbicidal concentration (MMC) of the above extract and compounds on a panel of bacterial species. The results of the MIC determinations demonstrated that the methanol extract as well as compounds 3 and 8 were able to prevent the growth of all the fourteen studied microorganisms within the concentration range of 4 to 1024 μg/ml. The lowest MIC value for the methanol extract (64 μg/ml) was obtained on Candida albicans. The lowest value for individual compounds (4 μg/ml) was recorded with compounds 3 on Pseudomonas aeruginosa PA01 and 7 on Eschericia coli ATCC strain. The MIC values recorded with compounds 3 on P. aeruginosa PA01, 6 on C. albicans,7 on P. aeruginosa PA01 and K. pneumoniae ATCC strain and C. albicans,and 8 on P. aeruginosa PA01, PA124, P. stuartii, M. tuberculosis MTCS1 were lower than or equal to those of the reference drugs. MMC values not greater than 1024 μg/ml were recorded on all studied microorganisms with compounds 3 and 8.
    CONCLUSIONS:
    The overall results of the present investigation provided evidence that the crude extract of D. mannii as well as some of its compounds such compounds 3 and 8 could be a potential source of natural antimicrobial products.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.0826 mL 15.4131 mL 30.8261 mL 61.6523 mL 77.0654 mL
    5 mM 0.6165 mL 3.0826 mL 6.1652 mL 12.3305 mL 15.4131 mL
    10 mM 0.3083 mL 1.5413 mL 3.0826 mL 6.1652 mL 7.7065 mL
    50 mM 0.0617 mL 0.3083 mL 0.6165 mL 1.233 mL 1.5413 mL
    100 mM 0.0308 mL 0.1541 mL 0.3083 mL 0.6165 mL 0.7707 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    补骨脂色烯查耳酮; Bavachromene CFN92219 41743-38-8 C20H18O4 = 322.4 5mg QQ客服:215959384
    异补骨脂色烯查耳酮; Isobavachromene CFN92220 52801-22-6 C20H18O4 = 322.4 5mg QQ客服:215959384
    黄腐酚C; Xanthohumol C CFN91509 189299-05-6 C21H20O5 = 352.4 5mg QQ客服:2056216494
    Dorsmanin A; Dorsmanin A CFN96193 162229-27-8 C20H20O4 = 324.4 5mg QQ客服:2159513211
    黄腐醇B; Xanthohumol B CFN91956 189308-10-9 C21H22O6 = 370.40 5mg QQ客服:2159513211
    黄腐醇I; Xanthohumol I CFN91958 688360-06-7 C21H22O6 = 370.40 5mg QQ客服:215959384
    黄腐醇L; Xanthohumol L CFN91957 688360-15-8 C21H22O6 = 370.40 5mg QQ客服:2056216494
    Isodorsmanin A; Isodorsmanin A CFN96199 118266-99-2 C20H20O4 = 324.4 5mg QQ客服:1413575084
    补骨脂呋喃查耳酮; Bakuchalcone CFN92229 84575-13-3 C20H20O5 = 340.4 5mg QQ客服:215959384
    Brosimacutin G; Brosimacutin G CFN92230 350221-50-0 C20H20O6 = 356.4 5mg QQ客服:2056216494

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