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  • 氯化飞燕草素

    Delphinidin chloride

    氯化飞燕草素
    产品编号 CFN92033
    CAS编号 528-53-0
    分子式 = 分子量 C15H11ClO7 = 338.7
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Flavonoids
    植物来源 The fruits of Vaccinium myrtillus
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    氯化飞燕草素 CFN92033 528-53-0 1mg QQ客服:1457312923
    氯化飞燕草素 CFN92033 528-53-0 5mg QQ客服:1457312923
    氯化飞燕草素 CFN92033 528-53-0 10mg QQ客服:1457312923
    氯化飞燕草素 CFN92033 528-53-0 20mg QQ客服:1457312923
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • S.N.D.T. Women's University (India)
  • Kazusa DNA Research Institute (Japan)
  • Complutense University of Madrid (Spain)
  • Heidelberg University (Germany)
  • Lund University (Sweden)
  • University of Eastern Finland (Finland)
  • Utah State University (USA)
  • University of Brasilia (Brazil)
  • VIB Department of Plant Systems Biology, UGent (PSB) (Belgium)
  • Universidade do Porto (Portugal)
  • Korea Institute of Oriental Medicine (Korea)
  • Kamphaengphet Rajabhat University (Thailand)
  • University of Melbourne (Australia)
  • University of Maryland School of Medicine (USA)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Food Chem.2020, 313:126079
  • Nat Commun.2019, 10(1):2745
  • Foods.2020, 9(10):1348.
  • J Ethnopharmacol.2023, 321:117501.
  • J. of The Korean Society of Food Culture2017, 144-149
  • Separations2021, 8(1), 1.
  • Korean J. Medicinal Crop Sci.2021, 29(1):45-50.
  • Molecules.2023, 28(19):6775.
  • Evid Based Complement Alternat Med.2016, 2016:1739760
  • J Korean Med Ophthalmol Otolaryngol Dermatol2023, 36(1):21-39.
  • Molecules.2023, 28(7):3039.
  • Phytomedicine.2015, 22(11):1027-36
  • Chem Biol Interact.2018, 290:44-51
  • bioRxiv - Biochemistry2023, 548213.
  • J Chromatogr B Analyt Technol Biomed Life Sci.2019, 1124:323-330
  • J Agric Food Chem.2021, 69(11):3496-3510.
  • Appl. Sci.2020, 10(20), 7323.
  • Food Research International2016, 106-113
  • Vietnam Journal of Food Control.2022, 5(3):pp.488-497.
  • J Chromatogr Sci.2015, 53(5):824-9
  • Inflammation.2015, 38(4):1502-16
  • J Ethnopharmacol.2019, 244:112074
  • Tissue Cell.2022, 75:101728.
  • ...
  • 生物活性
    Description: Delphinidin chloride is a dietary antioxidant. Delphinidin is a naturally occurring inhibitor of vascular endothelial growth factor receptors, possesses important antiangiogenic properties that may be helpful for the prevention and treatment of cancer.
    Targets: VEGFR
    In vitro:
    Environ Toxicol . 2021 Aug;36(8):1557-1566.
    Delphinidin modulates JAK/STAT3 and MAPKinase signaling to induce apoptosis in HCT116 cells[Pubmed: 33955636]
    Abstract Delphinidin is an anthocyanin that belongs to the group of flavonoids that exert numerous biological activities. However, the molecular mechanisms underlying the anticancer effects of delphinidin remain poorly understood. In our study we analyzed delphinidin modulate STAT-3 and MAPKinase signaling thereby inhbits cell proliferation and promote apoptosis. Our study demonstrated that delphinidin treatment significantly reduced the viability of human colon cancer HCT116 in a concentration-dependent manner. We noticed that delphinidin effectively induced oxidative stress-mediated apoptosis by generating intracellular ROS, decreasing antioxidant levels, inducing lipid peroxidation, and single-strand break on colon cancer cells. In this study, we observed that delphinidin treatment alters the mitochondrial membrane potential, thereby induces apoptosis was closely associated with the induction of pro-apoptotic Bax, Caspase- 3,8 & 9, cytochrome C, and inhibition of anti-apoptotic protein expression. Studies on STAT-3 and MAPKinase signaling showed delphinidin inhibited the phosphorylation of these transcription factors' activity. Inhibition of STAT-3, p38, and ERK1/2 phosphorylation and modulation pro-apoptotic protein expression might be responsible for the anticancer activity of delphinidin in colon cancer cells.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.9525 mL 14.7623 mL 29.5247 mL 59.0493 mL 73.8116 mL
    5 mM 0.5905 mL 2.9525 mL 5.9049 mL 11.8099 mL 14.7623 mL
    10 mM 0.2952 mL 1.4762 mL 2.9525 mL 5.9049 mL 7.3812 mL
    50 mM 0.059 mL 0.2952 mL 0.5905 mL 1.181 mL 1.4762 mL
    100 mM 0.0295 mL 0.1476 mL 0.2952 mL 0.5905 mL 0.7381 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    = 5mg QQ客服:2056216494
    氯化失车菊素-3-O-葡萄糖苷; Cyanidin-3-O-glucoside chloride CFN99740 7084-24-4 C21H21O11 = 449.38 20mg QQ客服:1413575084
    氯化矢车菊素-3-O-阿拉伯糖苷; Cyanidin-3-O-arabinoside chloride CFN92041 111613-04-8 C20H19ClO10 = 454.8 10mg QQ客服:1457312923
    氯化失车菊素-3-O-半乳糖苷; Cyanidin-3-O-galactoside chloride CFN92040 27661-36-5 C21H21ClO11 = 484.9 10mg QQ客服:2056216494
    氯化失车菊素-3-O-桑布双糖苷; Cyanidin-3-O-sambubioside chloride CFN92173 33012-73-6 C26H29ClO15 = 617.0 10mg QQ客服:215959384
    矢车菊素-3-O-桑布双糖苷-5-O-葡萄糖苷; Cyanidin-3-O-sambubioside-5-O-glucoside chloride CFN91865 53925-33-0 C32H39ClO20 = 779.1 10mg QQ客服:1413575084
    氯化失车菊素-3,5-O-双葡萄糖苷; Cyanidin-3,5-O-diglucoside chloride CFN92138 2611-67-8 C27H31O16Cl = 647.0 10mg QQ客服:215959384
    氯化失车菊素-3-O-芸香糖苷; Cyanidin-3-O-rutinoside chloride CFN92135 18719-76-1 C27H31O15Cl = 630.98 10mg QQ客服:215959384
    氯化矢车菊素-3-O-槐糖苷; Cyanidin 3-sophoroside chloride CFN90469 18376-31-3 C27H31O16.Cl = 646.99 5mg QQ客服:1457312923
    氯化矢车菊素-3-O-(6''-丙二酰葡糖苷); Cyanidin-3-O-(6''-malonylglucoside) chloride CFN91864 171828-62-9 C24H23ClO14 = 570.9 5mg QQ客服:2159513211

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