D(+)-阿拉伯糖醇
D-arabinitol
|
|
产品编号 |
CFN98779 |
| CAS编号 |
488-82-4 |
| 分子式 = 分子量 |
C5H12O5 = 152.1 |
| 产品纯度 |
>=98% |
| 物理属性 |
Cryst. |
| 化合物类型 |
Miscellaneous |
| 植物来源 |
The barks of Eucommia ulmoides Oliver |
| ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用 |
|
| 产品名称 |
产品编号 |
CAS编号 |
包装 |
QQ客服 |
| D(+)-阿拉伯糖醇 |
CFN98779 |
488-82-4 |
10mg |
QQ客服：3257982914 |
| D(+)-阿拉伯糖醇 |
CFN98779 |
488-82-4 |
20mg |
QQ客服：3257982914 |
| D(+)-阿拉伯糖醇 |
CFN98779 |
488-82-4 |
50mg |
QQ客服：3257982914 |
| D(+)-阿拉伯糖醇 |
CFN98779 |
488-82-4 |
100mg |
QQ客服：3257982914 |
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ChemFaces的产品在许多优秀和顶级科学期刊中被引用
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
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国外学术期刊发表的引用ChemFaces产品的部分文献
Int J Mol Sci. 2014, 15(5):8443-57
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J Nat Med.2018, 72(3):734-744
Antibiotics.2022, 11(4), 510.
Phytomedicine.2019, 55:229-237
Front Plant Sci.2020, 11:630.
Foods.2022, 11(12):1773.
| Description: |
D-arabinitol is a marker for the diagnosis of disseminated candidiasis and for monitoring response to antifungal therapy. |
| In vivo: |
| J Med Vet Mycol. 1994;32(3):205-15. | | Serum D-arabinitol measured by automated quantitative enzymatic assay for detection and therapeutic monitoring of experimental disseminated candidiasis: correlation with tissue concentrations of Candida albicans.[Pubmed: 7965491] | In order to further understand serum D-arabinitol (DA) as a marker for the diagnosis of disseminated candidiasis and for monitoring response to antifungal therapy, we studied the serum levels of this Candida carbohydrate metabolite by rapid automated enzymatic assay in rabbits with experimental disseminated candidiasis. As a correction for renal impairment, data were expressed as serum D-arabinitol/creatinine ratio (D-arabinitol/Cr). Serum creatinine concentrations were determined from the same sample with the same instrument, thereby allowing rapid determination of the D-arabinitol/Cr within one laboratory.
METHODS AND RESULTS:
The D-arabinitol/Cr was determined in 321 samples from 132 rabbits. The mean serum D-arabinitol/Cr in 31 normal non-infected rabbits was 1.51 +/- 0.2 microM mg-1 dl-1. Among 84 rabbits with disseminated candidiasis and pre-terminal samples, there was a direct correlation between D-arabinitol/Cr and tissue concentration of Candida albicans (r = 0.80; P < 0.001). A threshold of elevated D-arabinitol/Cr (> or = 3.0 microM mg-1 dl-1) was evident in rabbits with a tissue concentration of C. albicans > or = 3 x 10(4) colony forming units (CFU) g-1. Elevated D-arabinitol/Cr was detected in 48 (89%) of 54 rabbits at a C. albicans tissue concentration of > or = 3 x 10(4) CFU g-1 vs. The relationship between the tissue response to antifungal therapy and change in D-arabinitol/Cr was then further analysed. Ten (91%) of 11 rabbits with a tissue-proven response to antifungal therapy (defined as > or = 10(2)-fold reduction of CFU g-1 in comparison to untreated controls) had a > 50% reduction in elevated D-arabinitol/Cr levels. By comparison, 10 (83%) of 12 treated rabbits with no response to therapy had persistently elevated D-arabinitol/Cr levels (P < 0.001).
CONCLUSIONS:
These findings provide an experimental basis for understanding the patterns of expression of serum D-arabinitol in disseminated candidiasis and further indicate that serial D-arabinitol/Cr measurements may be useful for diagnosis and therapeutic monitoring of disseminated candidiasis. |
|
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
6.5746 mL |
32.8731 mL |
65.7462 mL |
131.4924 mL |
164.3655 mL |
| 5 mM |
1.3149 mL |
6.5746 mL |
13.1492 mL |
26.2985 mL |
32.8731 mL |
| 10 mM |
0.6575 mL |
3.2873 mL |
6.5746 mL |
13.1492 mL |
16.4366 mL |
| 50 mM |
0.1315 mL |
0.6575 mL |
1.3149 mL |
2.6298 mL |
3.2873 mL |
| 100 mM |
0.0657 mL |
0.3287 mL |
0.6575 mL |
1.3149 mL |
1.6437 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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