D-(-)-奎宁酸

D-(-)-Quinic acid

	产品编号	CFN99930
	CAS编号	77-95-2
	分子式 = 分子量	C₇H₁₂O₆ = 192.17
	产品纯度	>=98%
	物理属性	Powder
	化合物类型	Miscellaneous
	植物来源	The fruits of Citrus limon (L.) Burm. f.
ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用

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产品名称	产品编号	CAS编号	包装	QQ客服
D-(-)-奎宁酸	CFN99930	77-95-2	10mg	QQ客服：1457312923
D-(-)-奎宁酸	CFN99930	77-95-2	20mg	QQ客服：1457312923
D-(-)-奎宁酸	CFN99930	77-95-2	50mg	QQ客服：1457312923
D-(-)-奎宁酸	CFN99930	77-95-2	100mg	QQ客服：1457312923

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ChemFaces的产品在许多优秀和顶级科学期刊中被引用

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089

Korea Institute of Oriental Medicine (Korea)

Stanford University (USA)

Fraunhofer-Institut für Molekularbiologie und Angewandte ?kologie IME (Germany)

University of Bonn (Germany)

VIT University (India)

MTT Agrifood Research Finland (Finland)

Universidade Federal de Santa Catarina (Brazil)

The Institute of Cancer Research (United Kingdom)

Lund University (Sweden)

Seoul National University (Korea)

University of Malaya (Malaysia)

Uniwersytet Jagielloński w Krakowie (Poland)

Helmholtz Zentrum München (Germany)

University of Amsterdam (Netherlands)

More...

Description:

D-(-)-Quinic acid is a cellular metal ion chelator, capable of promoting reactions with metal M(II,III) ions under pH-specific conditions. It may possess potent inhibition against alpha-mannosidase and alpha-fucosidase.

Targets:

Beta Amyloid | alpha-mannosidase | alpha-fucosidase

In vivo:

Mol Nutr Food Res. 2011 Mar;55(3):368-77.

Colonic availability of polyphenols and D-(-)-quinic acid after apple smoothie consumption.[Pubmed: 21370449]

The aim of this study was to determine the amounts of polyphenols and D-(-)-Quinic acid reaching the ileostomy bags of probands (and thus the colon in healthy humans) after ingestion of apple smoothie, a beverage containing 60% cloudy apple juice and 40% apple puree.
METHODS AND RESULTS:
Ten healthy ileostomy subjects each ingested 0.7 L of apple smoothie (a bottle). Their ileostomy bags were collected directly before and 1, 2, 4, 6 and 8 h after smoothie consumption, and the polyphenol and D-(-)-Quinic acid contents of the ileostomy fluids were examined using HPLC-DAD and HPLC-MS/MS. The total polyphenol and D-(-)-Quinic acid content of the apple smoothie was determined to be 1955.6±124.6 mg/0.7 L, which is very high compared to cloudy apple juices. The most abundant substances found in the ileostomy bags were oligomeric procyanidins (705.6±197.9 mg), D-(-)-Quinic acid (363.4±235.5 mg) and 5-caffeoylquinic acid (76.7±26.8 mg). Overall recovery of ingested polyphenols and D-(-)-Quinic acid in the ileostomy bags was 63.3±16.1%.
CONCLUSIONS:
The amounts of polyphenol and D-(-)-Quinic acids reaching the ileostomy bags are considerably higher after apple smoothie consumption than after the consumption of cloudy apple juice or cider. These results suggest that the food matrix might affect the colonic availability of polyphenols, and apple smoothies could be more effective in the prevention of chronic colon diseases than both cloudy apple juice and apple cider.

产品名称	产品编号	CAS编号	分子式 = 分子量	位单	联系QQ
去氧野艽霉素盐酸盐; Deoxynojirimycin hydrochloride	CFN90484	73285-50-4	C₆H₁₄ClNO₄ = 199.6	5mg	QQ客服：215959384
环己五醇, L-栎醇; vibo-Quercitol	CFN98778	488-76-6	C₆H₁₂O₅ = 164.2	20mg	QQ客服：1457312923
肌醇; Inositol	CFN91718	87-89-8	C₆H₁₂O₆ = 180.16	20mg	QQ客服：2056216494
(E)-1-甲氧基-2-O-(p-香豆酰)-myo-肌醇; (E)-1-methoxy-2-O-(p-coumaroyl)-myo-inositol	CFN95609	1391715-18-6	C₁₆H₂₀O₈ = 340.3	20mg	QQ客服：1413575084
D-松醇; D-Pinitol	CFN99044	10284-63-6	C₇H₁₄O₆ = 194.2	20mg	QQ客服：215959384
(-)-白雀木醇; L-Quebrachitol	CFN90586	642-38-6	C₇H₁₄O₆ = 194.18	5mg	QQ客服：1413575084
牛弥菜醇A; Conduritol A	CFN98868	526-87-4	C₆H₁₀O₄ = 146.1	10mg	QQ客服：1457312923
D-(-)-奎宁酸; D-(-)-Quinic acid	CFN99930	77-95-2	C₇H₁₂O₆ = 192.17	20mg	QQ客服：2056216494
莽草酸; Shikimic acid	CFN99436	138-59-0	C₇H₁₀O₅ = 174.2	20mg	QQ客服：2159513211
3,4-O-异亚丙基莽草酸; 3,4-O-Isopropylidene shikimic acid	CFN99852	183075-03-8	C₁₀H₁₄O₅ = 214.2	5mg	QQ客服：2056216494

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	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	5.2037 mL	26.0186 mL	52.0373 mL	104.0745 mL	130.0931 mL
5 mM	1.0407 mL	5.2037 mL	10.4075 mL	20.8149 mL	26.0186 mL
10 mM	0.5204 mL	2.6019 mL	5.2037 mL	10.4075 mL	13.0093 mL
50 mM	0.1041 mL	0.5204 mL	1.0407 mL	2.0815 mL	2.6019 mL
100 mM	0.052 mL	0.2602 mL	0.5204 mL	1.0407 mL	1.3009 mL