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  • D-(-)-奎宁酸

    • D-(-)-奎宁酸

    D-(-)-Quinic acid

    D-(-)-奎宁酸
    		产品编号 CFN99930
    CAS编号 77-95-2
    分子式 = 分子量 C7H12O6 = 192.17
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Miscellaneous
    植物来源 The fruits of Citrus limon (L.) Burm. f.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    D-(-)-奎宁酸 CFN99930 77-95-2 10mg QQ客服：3257982914
    D-(-)-奎宁酸 CFN99930 77-95-2 20mg QQ客服：3257982914
    D-(-)-奎宁酸 CFN99930 77-95-2 50mg QQ客服：3257982914
    D-(-)-奎宁酸 CFN99930 77-95-2 100mg QQ客服：3257982914
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
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    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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    • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Journal of Third Military Medical University2019, 41(2):110-115
  • J.the Korean Socie. Food Sci.&Nut.2023; 52(1):26-39.
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  • Sustainable Chemistry & Pharmacy2022, 30:100883.
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  • Pharmaceutics.2021, 13(11):1839.
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  • Srinakharinwirot University2023, 2669.
  • J Agric Food Chem.2021, 69(14):4210-4222.
  • Phytomedicine.2019, 58:152893
  • J. Pharm. Res. Int.2022, 34(58): pp.1-14.
  • J Med Food.2022, 25(3):272-280.
  • Front Plant Sci.2020, 11:630.
  • Front Plant Sci.2022, 12:811166.
  • J Ethnopharmacol.2017, 196:75-83
  • J Sci Food Agric.2018, 98(3):1153-1161
  • Environ Toxicol.2024, 39(3):1556-1566.
  • ...
    • 生物活性
    Description: D-(-)-Quinic acid is a cellular metal ion chelator, capable of promoting reactions with metal M(II,III) ions under pH-specific conditions. It may possess potent inhibition against alpha-mannosidase and alpha-fucosidase.
    Targets: Beta Amyloid | alpha-mannosidase | alpha-fucosidase
    In vivo:
    Mol Nutr Food Res. 2011 Mar;55(3):368-77.
    Colonic availability of polyphenols and D-(-)-quinic acid after apple smoothie consumption.[Pubmed: 21370449]
    The aim of this study was to determine the amounts of polyphenols and D-(-)-Quinic acid reaching the ileostomy bags of probands (and thus the colon in healthy humans) after ingestion of apple smoothie, a beverage containing 60% cloudy apple juice and 40% apple puree.
    METHODS AND RESULTS:
    Ten healthy ileostomy subjects each ingested 0.7 L of apple smoothie (a bottle). Their ileostomy bags were collected directly before and 1, 2, 4, 6 and 8 h after smoothie consumption, and the polyphenol and D-(-)-Quinic acid contents of the ileostomy fluids were examined using HPLC-DAD and HPLC-MS/MS. The total polyphenol and D-(-)-Quinic acid content of the apple smoothie was determined to be 1955.6±124.6 mg/0.7 L, which is very high compared to cloudy apple juices. The most abundant substances found in the ileostomy bags were oligomeric procyanidins (705.6±197.9 mg), D-(-)-Quinic acid (363.4±235.5 mg) and 5-caffeoylquinic acid (76.7±26.8 mg). Overall recovery of ingested polyphenols and D-(-)-Quinic acid in the ileostomy bags was 63.3±16.1%.
    CONCLUSIONS:
    The amounts of polyphenol and D-(-)-Quinic acids reaching the ileostomy bags are considerably higher after apple smoothie consumption than after the consumption of cloudy apple juice or cider. These results suggest that the food matrix might affect the colonic availability of polyphenols, and apple smoothies could be more effective in the prevention of chronic colon diseases than both cloudy apple juice and apple cider.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 5.2037 mL 26.0186 mL 52.0373 mL 104.0745 mL 130.0931 mL
    5 mM 1.0407 mL 5.2037 mL 10.4075 mL 20.8149 mL 26.0186 mL
    10 mM 0.5204 mL 2.6019 mL 5.2037 mL 10.4075 mL 13.0093 mL
    50 mM 0.1041 mL 0.5204 mL 1.0407 mL 2.0815 mL 2.6019 mL
    100 mM 0.052 mL 0.2602 mL 0.5204 mL 1.0407 mL 1.3009 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    去氧野艽霉素盐酸盐; Deoxynojirimycin hydrochloride CFN90484 73285-50-4 C6H14ClNO4 = 199.6 5mg QQ客服：215959384
    环己五醇, L-栎醇; vibo-Quercitol CFN98778 488-76-6 C6H12O5 = 164.2 20mg QQ客服：2056216494
    肌醇; Inositol CFN91718 87-89-8 C6H12O6 = 180.16 20mg QQ客服：1413575084
    (E)-1-甲氧基-2-O-(p-香豆酰)-myo-肌醇; (E)-1-methoxy-2-O-(p-coumaroyl)-myo-inositol CFN95609 1391715-18-6 C16H20O8 = 340.3 20mg QQ客服：2056216494
    D-松醇; D-Pinitol CFN99044 10284-63-6 C7H14O6 = 194.2 20mg QQ客服：215959384
    (-)-白雀木醇; L-Quebrachitol CFN90586 642-38-6 C7H14O6 = 194.18 5mg QQ客服：1413575084
    牛弥菜醇A; Conduritol A CFN98868 526-87-4 C6H10O4 = 146.1 10mg QQ客服：1413575084
    D-(-)-奎宁酸; D-(-)-Quinic acid CFN99930 77-95-2 C7H12O6 = 192.17 20mg QQ客服：3257982914
    莽草酸; Shikimic acid CFN99436 138-59-0 C7H10O5 = 174.2 20mg QQ客服：2056216494
    3,4-O-异亚丙基莽草酸; 3,4-O-Isopropylidene shikimic acid CFN99852 183075-03-8 C10H14O5 = 214.2 5mg QQ客服：215959384

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