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  • 紫菫定酚

    Corydine

    紫菫定酚
    产品编号 CFN90527
    CAS编号 476-69-7
    分子式 = 分子量 C20H23NO4 = 341.40
    产品纯度 >=98%
    物理属性 Solid
    化合物类型 Alkaloids
    植物来源 The tubers of Corydalis tuberosa DC.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    紫菫定酚 CFN90527 476-69-7 1mg QQ客服:1413575084
    紫菫定酚 CFN90527 476-69-7 5mg QQ客服:1413575084
    紫菫定酚 CFN90527 476-69-7 10mg QQ客服:1413575084
    紫菫定酚 CFN90527 476-69-7 20mg QQ客服:1413575084
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Amity University (India)
  • University of Madras (India)
  • Max Rubner-Institut (MRI) (Germany)
  • Wageningen University (Netherlands)
  • Uniwersytet Medyczny w ?odzi (Poland)
  • Auburn University (USA)
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  • Universit?t Basel (Switzerland)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Nutrients.2021, 13(1):254.
  • Postharvest Biol Tec2019, 149:18-26
  • Molecules.2019, 24(10):E1930
  • Plant Cell,Tissue & Organ Culture2016, 127(1):115-121
  • Food Chem.2019, 275:746-753
  • Evid Based Complement Alternat Med.2018, 2018:1073509
  • Comput Biol Chem.2019, 83:107096
  • Food Funct.2022, 13(23):12105-12120.
  • Journal of Analytical Chemistry2017, 854-861
  • J of Ana. Chem.2019, 74(11):1113-1121
  • Biomed Pharmacother.2019, 116:108987
  • Int J Pharmacol2020, 16:1-9
  • Konkuk University2023, 29:4634721
  • Fitoterapia.2024, 106006.
  • bioRxiv-Pharm.&Toxi.2022, 2022.481203.
  • Emirates Journal of Food and Agriculture.2022, 34(6): 528-536.
  • Molecules.2023, 28(8):3414.
  • Molecules.2018, 23(7):E1817
  • University of Manitoba2023, 37433.
  • Microb Pathog.2019, 131:128-134
  • PLoS One.2017, 12(8):e0181191
  • J Sci Food Agric.2023, 103(1):213-220.
  • Food Research International2020, 108987
  • ...
  • 生物活性
    Description: Corydine is the adrenolytic and weak cholinergic agent, it shows antimicrobial, and antineoplastic activities. Corydine shows irritant and respiratory stimulant and CNS depressant activities. Injected intravenously in rabbits corydine produced an initial fall in blood pressure followed by a return to normal or above normal.
    Targets: IL Receptor | Antifection
    In vitro:
    J Pharmacobiodyn. 1990 Jul;13(7):426-31.
    Suppression of tumor cell growth and mitogen response by aporphine alkaloids, dicentrine, glaucine, corydine, and apomorphine.[Pubmed: 2290126]

    METHODS AND RESULTS:
    The aporphine alkaloids, dicentrine, glaucine, Corydine, and apomorphine were shown to have inhibitory activity against several mouse tumor cell lines, leukemia P388 and L1210, melanoma B16, bladder cancer MBC2, and colon cancer Colon 26 in culture. These aporphine alkaloids also inhibited the mitogen-induced lymphocyte proliferation as well as the growth of IL-2 dependent CTLL2 line in a dose-dependent way. Of the four alkaloids apomorphine proved to be most potent in the inhibitory action.
    CONCLUSIONS:
    Apomorphine treatment resulted in some prolongation of survival time of the mice inoculated i.p. with P388, although its activity was not enough to meet the standard criterion for antitumor activity.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.9291 mL 14.6456 mL 29.2912 mL 58.5823 mL 73.2279 mL
    5 mM 0.5858 mL 2.9291 mL 5.8582 mL 11.7165 mL 14.6456 mL
    10 mM 0.2929 mL 1.4646 mL 2.9291 mL 5.8582 mL 7.3228 mL
    50 mM 0.0586 mL 0.2929 mL 0.5858 mL 1.1716 mL 1.4646 mL
    100 mM 0.0293 mL 0.1465 mL 0.2929 mL 0.5858 mL 0.7323 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    N-甲基钓樟卡品; N-Methyllindcarpine CFN99454 14028-97-8 C19H21NO4 = 327.4 5mg QQ客服:2056216494
    异紫堇定碱; (+)-Isocorynoline CFN90215 475-67-2 C20H23NO4 = 341.40 20mg QQ客服:2159513211
    紫菫定酚; Corydine CFN90527 476-69-7 C20H23NO4 = 341.40 5mg QQ客服:1457312923
    紫堇块茎碱; Corytuberine CFN90528 517-56-6 C19H21NO4 = 327.37 5mg QQ客服:215959384
    N-甲基-O10-甲基莲叶桐文; Litseglutine B CFN98279 25368-01-8 C20H23NO4 = 341.4 5mg QQ客服:1457312923
    波尔定碱; Boldine CFN98718 476-70-0 C19H21NO4 = 327.4 20mg QQ客服:2056216494
    无根藤辛; Cassythicine CFN98998 5890-28-8 C19H19NO4 = 325.4 5mg QQ客服:3257982914
    海罂粟碱; Glaucine CFN90408 475-81-0 C21H25NO4 = 355.43 20mg QQ客服:215959384
    波尔定碱 2-甲醚; Lauroscholtzine CFN98078 2169-44-0 C20H23NO4 = 341.4 5mg QQ客服:2159513211
    Nantenine; Nantenine CFN89514 2565-01-7 C20H21NO4 = 339.38 5mg QQ客服:215959384

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