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  • 柠檬油素

    Citropten

    柠檬油素
    产品编号 CFN97963
    CAS编号 487-06-9
    分子式 = 分子量 C11H10O4 = 206.2
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Coumarins
    植物来源 The peels of Citrus medica L.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    柠檬油素 CFN97963 487-06-9 10mg QQ客服:2056216494
    柠檬油素 CFN97963 487-06-9 20mg QQ客服:2056216494
    柠檬油素 CFN97963 487-06-9 50mg QQ客服:2056216494
    柠檬油素 CFN97963 487-06-9 100mg QQ客服:2056216494
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Lund University (Sweden)
  • Medizinische Universit?t Wien (Austria)
  • Medical University of South Carolina (USA)
  • Universiti Putra Malaysia(UPM) (Malaysia)
  • University of Amsterdam (Netherlands)
  • University of Melbourne (Australia)
  • Universiti Malaysia Pahang (Malaysia)
  • Celltrion Chemical Research Institute (Korea)
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  • The Vancouver Prostate Centre (VPC) (Canada)
  • Universitas islam negeri Jakarta (Indonesia)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Nutrients2020, 12(3):811.
  • An Acad Bras Cienc.2023, 95(3):e20220672
  • Anal Bioanal Chem.2023, 415(9):1641-1655.
  • Biochem Biophys Res Commun.2020, 522(4):1052-1058
  • Nutrients.2018, 11(1):E17
  • J of the Korean Society of Cosmetics and Cosmetology2019, 225-231
  • Pamukkale Medical Journal2022, 15(4):796-803.
  • Food Chem.2017, 228:301-314
  • Appl Biochem Biotechnol.2022, s12010-022-04166-2.
  • Tissue Cell.2022, 75:101728.
  • Int J Med Sci.2020, 17(5):626-631
  • Antioxidants (Basel).2021, 10(9):1487.
  • Phytother Res.2019, 33(4):1104-1113
  • Biomedicines.2020, 8(11):486.
  • Genes (Basel).2021, 12(7):1024.
  • BMC Cancer. 2021, 21(1):91.
  • United States Patent Application2020, 20200038363
  • J Food Sci Technol.2019, 56(5):2712-2720
  • Industrial Food Engineering2015, 19(4):408-413
  • Asian J of Pharmaceutical&Clinical 2018, 11(2)
  • Food Sci Nutr.2023, 00:1-10.
  • Separation Science Plus2022, sscp.202200048.
  • Curr Issues Mol Biol.2023, 45(3):2136-2156.
  • ...
  • 生物活性
    Description: Citropten and valproic acid show antiproliferative effects against A2058 human melanoma cells.
    In vitro:
    Acta Pol Pharm. 2014 Nov-Dec;71(6):1056-9.
    Antiproliferative effect of valproic acid and 5,7-dimethoxycoumarin against A2058 human melanoma cells.[Pubmed: 25745779]
    Melanoma is one of the most malignant tumors of a dangerous high incidence and high metastatic potential. It grows quickly and in an advanced stage is resistant to radio-, chemo- and immunotherapy, which makes it difficult to cure. Therefore, research efforts are focused on the development of new therapeutics or chemopreventive strategies.
    METHODS AND RESULTS:
    The aim of the study was to investigate whether the valproic acid and 5,7-dimethoxycoumarin(Citropten) have an antiproliferative activity against A2058 human melanoma cell line.
    CONCLUSIONS:
    Investigated compounds inhibited the proliferation of cells, however, no synergistic effect of their co-administration was observed.
    J Photochem Photobiol B. 2016 Sep;162:402-11.
    Inactivation of plant-pathogenic fungus Colletotrichum acutatum with natural plant-produced photosensitizers under solar radiation.[Pubmed: 27434699 ]
    The increasing tolerance to currently used fungicides and the need for environmentally friendly antimicrobial approaches have stimulated the development of novel strategies to control plant-pathogenic fungi such as antimicrobial phototreatment (APT).
    METHODS AND RESULTS:
    We investigated the in vitro APT of the plant-pathogenic fungus Colletotrichum acutatum with furocoumarins and coumarins and solar radiation. The compounds used were: furocoumarins 8-methoxypsoralen (8-MOP) and 5,8-dimethoxypsoralen (isopimpinellin), coumarins 2H-chromen-2-one (coumarin), 7-hydroxycoumarin, 5,7-dimethoxycoumarin (citropten) and a mixture (3:1) of 7-methoxycoumarin and 5,7-dimethoxycoumarin. APT of conidia with crude extracts from 'Tahiti' acid lime, red and white grapefruit were also performed. Pure compounds were tested at 50μM concentration and mixtures and extracts at 12.5mgL(-1). The C. acutatum conidia suspension with or without the compounds was exposed to solar radiation for 1h. In addition, the effects of APT on the leaves of the plant host Citrus sinensis were determined. APT with 8-MOP was the most effective treatment, killing 100% of the conidia followed by the mixture of two coumarins and isopimpinellin that killed 99% and 64% of the conidia, respectively. APT with the extracts killed from 20% to 70% of the conidia, and the extract from 'Tahiti' lime was the most effective.
    CONCLUSIONS:
    No damage to sweet orange leaves was observed after APT with any of the compounds or extracts.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.8497 mL 24.2483 mL 48.4966 mL 96.9932 mL 121.2415 mL
    5 mM 0.9699 mL 4.8497 mL 9.6993 mL 19.3986 mL 24.2483 mL
    10 mM 0.485 mL 2.4248 mL 4.8497 mL 9.6993 mL 12.1242 mL
    50 mM 0.097 mL 0.485 mL 0.9699 mL 1.9399 mL 2.4248 mL
    100 mM 0.0485 mL 0.2425 mL 0.485 mL 0.9699 mL 1.2124 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    7-羟基-5-甲氧基香豆素; 5-Methoxy-7-hydroxycoumarin CFN92630 3067-10-5 C10H8O4 = 192.2 5mg QQ客服:1457312923
    柠檬油素; Citropten CFN97963 487-06-9 C11H10O4 = 206.2 20mg QQ客服:1413575084
    7-香叶草氧基-5-甲氧基香豆素; 7-Geranyloxy-5-methoxycoumarin CFN99003 1432075-68-7 C20H24O4 = 328.4 5mg QQ客服:3257982914
    5-香叶草氧基-7-甲氧基香豆素; 5-Geranoxy-7-methoxycoumarin CFN70446 7380-39-4 C20H24O4 = 328.4 5mg QQ客服:2056216494
    6-Hydroxymethylherniarin; 6-Hydroxymethylherniarin CFN92666 117597-79-2 C11H10O4 = 206.2 5mg QQ客服:2056216494
    7-羟基香豆素-6-羧酸; 7-Hydroxycoumarin-6-carboxylic acid CFN97325 833-52-3 C10H6O5 = 206.2 5mg QQ客服:2159513211
    6-Formyllimetin; 6-Formyllimetin CFN92511 88140-31-2 C12H10O5 = 234.2 5mg QQ客服:215959384

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