菊苣苷
Cichoriin
| 产品名称 |
产品编号 |
CAS编号 |
包装 |
QQ客服 |
| 菊苣苷 |
CFN95196 |
531-58-8 |
10mg |
QQ客服：2056216494 |
| 菊苣苷 |
CFN95196 |
531-58-8 |
20mg |
QQ客服：2056216494 |
| 菊苣苷 |
CFN95196 |
531-58-8 |
50mg |
QQ客服：2056216494 |
| 菊苣苷 |
CFN95196 |
531-58-8 |
100mg |
QQ客服：2056216494 |
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ChemFaces的产品在许多优秀和顶级科学期刊中被引用
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
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国外学术期刊发表的引用ChemFaces产品的部分文献
Biochemical Systematics and Ecology2018, 81
Nutrients.2018, 11(1):E17
Int. J. Mol. Sci.2023, 24(20),15294.
Processes2021, 9(5),831.
Int J Cosmet Sci.2022, doi:10.1111/ics.12827.
Biochem Pharmacol. 2020, 177:114014.
Vietnam Journal of Food Control.2022, 5(3):pp.488-497.
GENENCELL2023, 25:4356740
| Description: |
Cichoriin is a photosensitive compound, it could be used as herbal photosensitizing agent in treating benign breast tumor in rats. |
| In vitro: |
| International Journal of Biological Chemistry, 2009, 3(1):11-17. | | Cytoprotective Activity of Chemical Constituents Isolated from Streptomyces sp.[Reference: WebLink] |
METHODS AND RESULTS:
Four flavonoids including kaempferol (1), isoscutellarin (2), umbelliferone (3) and cichoriin (4) have been isolated from Streptomyces sp. Tc052, an endophyte in the root tissue of Alpinia galanga Swartz. The evaluation for protective effect of compounds 1-4 against glutamate-induced cytotoxicity in hippocampal HT22 cell line was conducted, Compounds 1 and 2 showed significant effective protection ratios of 62.4+2.8 and 55.3+3.4%, respectively, at a concentration of 100 μM, whereas compounds 3-4 were inactive. Compounds 1 and 2 showed potent scavenging effects on DPPH radical exhibiting IC50 value of 60.74 and 75.65 μM, respectively.
CONCLUSIONS:
These results suggest that compounds 1 and 2 may possess the neuroprotective activity against oxdative cellular injuries. |
|
| In vivo: |
| Electromagn Biol Med. 2012 Dec;31(4):299-309. | | Introducing Cichorium Pumilum as a potential therapeutical agent against drug-induced benign breast tumor in rats.[Pubmed: 22812448] | Cichorium Pumilum (chicory) is could be a promising cancer treatment in which a photosensitizing drug concentrates in benign tumor cells and activated by quanta at certain wavelength. Such activated extracts could lead to cell death and tumor ablation. Previous studies have shown that Cichorium Pumilum (chicory) contains photosensitive compounds such as
cichoriin, anthocyanins, lactucin, and Lactucopicrin.
METHODS AND RESULTS:
In the present study, the protective effect of sun light-activated Cichorium against the dimethylbenz[a]anthracene (DMBA) induced benign breast tumors to female Sprague-Dawley rats was investigated. Chicory's extract has significantly increase P.carbonyl (PC) and malondialdehyde (MDA) and decreases the hepatic levels of total antioxidant capacity (TAC) and superoxide dismutase (SOD) in benign breast tumors-induced group compared to control. It also significantly decrease the number of estrogen receptors ER-positive cells in tumor masses.
CONCLUSIONS:
These results suggest that chicory extracts could be used as herbal photosensitizing agent in treating benign breast tumor in rats. |
|
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
2.9386 mL |
14.6929 mL |
29.3858 mL |
58.7717 mL |
73.4646 mL |
| 5 mM |
0.5877 mL |
2.9386 mL |
5.8772 mL |
11.7543 mL |
14.6929 mL |
| 10 mM |
0.2939 mL |
1.4693 mL |
2.9386 mL |
5.8772 mL |
7.3465 mL |
| 50 mM |
0.0588 mL |
0.2939 mL |
0.5877 mL |
1.1754 mL |
1.4693 mL |
| 100 mM |
0.0294 mL |
0.1469 mL |
0.2939 mL |
0.5877 mL |
0.7346 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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