咖啡酸4-O-葡萄糖苷

Caffeic acid 4-O-glucoside

	产品编号	CFN91682
	CAS编号	166735-99-5
	分子式 = 分子量	C₁₅H₁₈O₉ = 342.3
	产品纯度	>=98%
	物理属性	Powder
	化合物类型	Phenols
	植物来源
ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用

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产品名称	产品编号	CAS编号	包装	QQ客服
咖啡酸4-O-葡萄糖苷	CFN91682	166735-99-5	1mg	QQ客服：1413575084
咖啡酸4-O-葡萄糖苷	CFN91682	166735-99-5	5mg	QQ客服：1413575084
咖啡酸4-O-葡萄糖苷	CFN91682	166735-99-5	10mg	QQ客服：1413575084
咖啡酸4-O-葡萄糖苷	CFN91682	166735-99-5	20mg	QQ客服：1413575084

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Description:

Caffeic acid 4-O-glucoside showed significant axonal elongation effects on Aβ25-35-induced atrophy. Caffeic acid 4-O-glucoside has inhibitory effects on the formation of advanced glycation end products (AGEs), the activity of angiotensin-converting (ACE) and acetylcholinesterase (AChE) enzymes.Caffeic acid 4-O-glucoside has radical-scavenging effect.

In vitro:

Biosci Biotechnol Biochem . 2010;74(9):1920-1924.

Biotransformation of cinnamic acid, p-coumaric acid, caffeic acid, and ferulic acid by plant cell cultures of Eucalyptus perriniana[Pubmed: 20834169]

Biotransformations of phenylpropanoids such as cinnamic acid, p-coumaric acid, caffeic acid, and ferulic acid were investigated with plant-cultured cells of Eucalyptus perriniana. The plant-cultured cells of E. perriniana converted cinnamic acid into cinnamic acid β-D-glucopyranosyl ester, p-coumaric acid, and 4-O-β-D-glucopyranosylcoumaric acid. p-Coumaric acid was converted into 4-O-β-D-glucopyranosylcoumaric acid, p-coumaric acid β-D-glucopyranosyl ester, 4-O-β-D-glucopyranosylcoumaric acid β-D-glucopyranosyl ester, a new compound, caffeic acid, and 3-O-β-D-glucopyranosylcaffeic acid. On the other hand, incubation of caffeic acid with cultured E. perriniana cells gave 3-O-β-D-glucopyranosylcaffeic acid, 3-O-(6-O-β-D-glucopyranosyl)-β-D-glucopyranosylcaffeic acid, a new compound, 3-O-β-D-glucopyranosylcaffeic acid β-D-glucopyranosyl ester, 4-O-β-D-glucopyranosylcaffeic acid, 4-O-β-D-glucopyranosylcaffeic acid β-D-glucopyranosyl ester, ferulic acid, and 4-O-β-D-glucopyranosylferulic acid. 4-O-β-D-Glucopyranosylferulic acid, ferulic acid β-D-glucopyranosyl ester, and 4-O-β-D-glucopyranosylferulic acid β-D-glucopyranosyl ester were isolated from E. perriniana cells treated with ferulic acid.

Food Chem . 2020 Jun 1;314:126181.

Polyphenols and inhibitory effects of crude and purified extracts from tomato varieties on the formation of advanced glycation end products and the activity of angiotensin-converting and acetylcholinesterase enzymes[Pubmed: 31954938]

The study analyzed the inhibitory effects (IC50) of crude and purified extracts from Maliniak, Cerise, Black Prince and Lima tomatoes on the formation of advanced glycation end products (AGEs), the activity of angiotensin-converting (ACE) and acetylcholinesterase (AChE) enzymes. Polyphenol composition (LC-MS) and antioxidant capacity (PCL, FRAP) were measured. The purified extracts of Black Prince tomatoes were the most potent inhibitors of AGEs in BSA-GLU (7.20mg/mL) and BSA-MGO (9.53mg/mL) models. The purified extracts of Cerise and Black Prince tomatoes had the highest ACE (0.50-0.44mg/mL) and AChE (7.93-5.83mg/mL) inhibitory activity. Cerise variety showed the highest polyphenol concentrations in crude (488.93μg/g DM) and purified (8394.99μg/g DM) extracts. The highest PCLACW and FRAP values were found for Cerise purified extracts (71.83 and 87.78μmol Trolox/g DM). Caffeic acid, caffeoyl-glucose, linocaffein, glucosyl-coumarate, vanillic acid, rutin and TPI values were significantly correlated with BSA-MGO, anti-ACE, anti-AChE and PCLACW parameters.

Nat Prod Res . 2015 Feb;29(3):262-267.

A new hemiterpene glycoside from the ripe tomatoes[Pubmed: 25421719]

A new hemiterpene glycoside (1) was isolated from ripe tomatoes (the fruit of Lycopersicon esculentum, Solanaceae) along with eight known compounds. The chemical structure of 1 was determined to be 2-methylbutan-1-ol β-d-glucopyranosyl-(1 → 6)-β-d-glucopyranoside, based on spectroscopic data as well as chemical evidence. In addition, the radical-scavenging activities of the isolated compounds on the free radical of 1,1-diphenyl-2-picrylhydrazyl were examined. Among the tested compounds, tryptophan, 4-O-β-d-glucopyranosyl caffeic acid and dihydro-p-coumaryl alcohol γ-O-β-d-glucopyranoside demonstrated 42.0%, 50.1% and 76.0% scavenging activities, respectively, at a concentration of 0.5 mM.

In vivo:

J Nat Prod . 2015 Sep 25;78(9):2297-2300.

Active Constituents from Drynaria fortunei Rhizomes on the Attenuation of Aβ(25-35)-Induced Axonal Atrophy[Pubmed: 26299900]

Axonal regeneration might contribute to the restoration of damaged neuronal networks and improvement of memory deficits in a murine Alzheimer's disease (AD) model. A search for axonal regenerative drugs was performed to discover novel therapeutic options for AD. In this study, an aqueous extract of Drynaria fortunei rhizomes reversed Aβ25-35-induced axonal atrophy in cultured cortical neurons of mice. Bioassay-guided fractionation of this extract led to the isolation and identification of compounds 1-5. Among them, (2S)-neoeriocitrin (2) and caffeic acid 4-O-glucoside (4) showed significant axonal elongation effects on Aβ25-35-induced atrophy.

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.9214 mL	14.6071 mL	29.2141 mL	58.4283 mL	73.0353 mL
5 mM	0.5843 mL	2.9214 mL	5.8428 mL	11.6857 mL	14.6071 mL
10 mM	0.2921 mL	1.4607 mL	2.9214 mL	5.8428 mL	7.3035 mL
50 mM	0.0584 mL	0.2921 mL	0.5843 mL	1.1686 mL	1.4607 mL
100 mM	0.0292 mL	0.1461 mL	0.2921 mL	0.5843 mL	0.7304 mL

产品名称	产品编号	CAS编号	分子式 = 分子量	位单	联系QQ
Caraganaphenol A; Caraganaphenol A	CFN95093	174916-31-5	C₅₆H₄₂O₁₃ = 923.0	5mg	QQ客服：2159513211
利奈唑胺; Linezolid	CFN60414	165800-03-3	C₁₆H₂₀FN₃O₄ = 337.35	5mg	QQ客服：215959384
Temsirolimus (CCI-779); Temsirolimus (CCI-779)	CFN60122	162635-04-3	C₅₆H₈₇NO₁₆ = 1030.29	5mg	QQ客服：215959384
3,4-二甲氧基苯乙酮; 3,4-Dimethoxyacetophenone	CFN70032	1131-62-0	C₁₀H₁₂O₃ = 180.2	20mg	QQ客服：215959384

咖啡酸4-O-葡萄糖苷

Caffeic acid 4-O-glucoside

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