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  • 中药标准品生产商,产品定制服务
  • 鬼箭羽碱,叶含卫矛碱

    Alatamine

    鬼箭羽碱,叶含卫矛碱
    产品编号 CFN92121
    CAS编号 41855-33-8
    分子式 = 分子量 C41H45NO18 = 839.8
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Sesquiterpenoids
    植物来源 The herbs of Ramulus euonymi.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    鬼箭羽碱,叶含卫矛碱 CFN92121 41855-33-8 1mg QQ客服:2159513211
    鬼箭羽碱,叶含卫矛碱 CFN92121 41855-33-8 5mg QQ客服:2159513211
    鬼箭羽碱,叶含卫矛碱 CFN92121 41855-33-8 10mg QQ客服:2159513211
    鬼箭羽碱,叶含卫矛碱 CFN92121 41855-33-8 20mg QQ客服:2159513211
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Northeast Normal University Changchun (China)
  • Monash University Malaysia (Malaysia)
  • National Chung Hsing University (Taiwan)
  • Donald Danforth Plant Science Center (USA)
  • Indian Institute of Science (India)
  • University of Wisconsin-Madison (USA)
  • Medical University of South Carolina (USA)
  • Tokyo Woman's Christian University (Japan)
  • Siksha O Anusandhan University (India)
  • Guangzhou Institutes of Biomedicine and Health (China)
  • University of Vienna (Austria)
  • Gyeongsang National University (Korea)
  • Nanjing University of Chinese Medicine (China)
  • Universitas islam negeri Jakarta (Indonesia)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Molecules2020, 25(4):892
  • Universidade Estadual Paulista2017, 42785
  • Pharmacia2022, 69(3): 883-890.
  • Int J Mol Sci.2017, 19(1)
  • Molecules.2019, 24(17):E3127
  • Mediators Inflamm. 2016, 2016:6189590
  • Evidence-based Compl.&Alternative Med.2023, 5417813
  • Nutrients.2021, 13(1):254.
  • Molecules.2022, 27(7):2116.
  • Curr Res Virol Sci.2022, 3:100019.
  • Saf Health Work.2019, 10(2):196-204
  • Chemistry of Natural Compounds2020, 56,423-426
  • Chem Biol Interact.2019, 298:1-7
  • J Chromatogr Sci.2015, 53(5):824-9
  • Br J Pharmacol.2016, 173(2):396-410
  • Institute of Food Science & Technology2021, 18 December.
  • Cell Biochem Funct.2018, 36(6):303-311
  • Front Pharmacol.2022, 13:883475.
  • Exp Biol Med (Maywood).2019, 244(18):1665-1679
  • Food Research2021, 5(1):65-71
  • TCI CO.2019, US20190151281A1
  • Plants (Basel).2020, 9(11):1535.
  • Int J Mol Sci.2021, 22(21):11836.
  • ...
  • 生物活性
    Description: Alatamine can markedly reduce acute myocardial ischemia (AMI)-induced cardiac injury and cardiac myocyte apoptosis, improve the expression and activity of sarcoplasmic/endoplasmic reticulum Ca(2+) ATPase (SERCA).
    Targets: Calcium Channel | ATPase | Bcl-2/Bax
    In vivo:
    Can. J.Physiol. Pharm., 2015, 94(4):433-40.
    Cardiac-protective effects and the possible mechanisms of alatamine during acute myocardial ischemia.[Pubmed: 26863576 ]
    Alatamine is a constituent in the extract of a traditional herbal medicine Ramulus euonymi widely used for cardiac protection.
    METHODS AND RESULTS:
    Mechanistically, it was also found that Alatamine improved the expression and activity of sarcoplasmic/endoplasmic reticulum Ca(2+) ATPase (SERCA), which were inhibited during AMI, promoting contractility and relaxation. Meanwhile, Alatamine decreased Bax and increased Bcl-2 expressions both in vivo and in vitro, therefore inhibiting cardiac myocyte apoptosis and preventing cardiac dysfunction caused by AMI at the cellular level.
    CONCLUSIONS:
    The present study revealed the beneficial role of Alatamine in cardiac protection and highlighted it as a potential therapeutic reagent for reduction of AMI-induced cardiac injury.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.1908 mL 5.9538 mL 11.9076 mL 23.8152 mL 29.769 mL
    5 mM 0.2382 mL 1.1908 mL 2.3815 mL 4.763 mL 5.9538 mL
    10 mM 0.1191 mL 0.5954 mL 1.1908 mL 2.3815 mL 2.9769 mL
    50 mM 0.0238 mL 0.1191 mL 0.2382 mL 0.4763 mL 0.5954 mL
    100 mM 0.0119 mL 0.0595 mL 0.1191 mL 0.2382 mL 0.2977 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    雷公藤宁碱A; Wilfornine A CFN92120 345954-00-9 C45H51NO20 = 925.9 5mg QQ客服:215959384
    雷公藤次碱; Wilforine CFN99207 11088-09-8 C43H49NO18 = 867.9 20mg QQ客服:215959384
    鬼箭羽碱,叶含卫矛碱; Alatamine CFN92121 41855-33-8 C41H45NO18 = 839.8 5mg QQ客服:215959384
    雷公藤定碱; Wilfordine CFN92103 37239-51-3 C43H49NO19 = 883.9 5mg QQ客服:3257982914
    Peritassine A; Peritassine A CFN92104 150881-01-9 C38H47NO18 = 805.8 5mg QQ客服:1457312923
    乌木叶碱 E-II; Ebenifoline E-II CFN92118 133740-16-6 C48H51NO18 = 929.9 5mg QQ客服:1457312923
    Mayteine; Mayteine CFN92119 104736-05-2 C43H49NO18 = 867.9 5mg QQ客服:215959384

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