Info: Read More
    		•
  • 中药标准品生产商，产品定制服务
    		•
  • 首页
  • 天然产物
  • 产品文献
  • 最新产品
  • 订购流程
  • 公司新闻
  • 公司简介
  • 联系我们
  • 首页
  • /
  • 天然产物（标准品）
  • /
  • 9-酮-泽兰素

    • 9-酮-泽兰素

    9-Oxoageraphorone

    9-酮-泽兰素
    		产品编号 CFN99071
    CAS编号 105181-06-4
    分子式 = 分子量 C15H22O2 = 234.3
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Sesquiterpenoids
    植物来源 The herbs of Eupatorium adenophorum
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    9-酮-泽兰素 CFN99071 105181-06-4 1mg QQ客服：215959384
    9-酮-泽兰素 CFN99071 105181-06-4 5mg QQ客服：215959384
    9-酮-泽兰素 CFN99071 105181-06-4 10mg QQ客服：215959384
    9-酮-泽兰素 CFN99071 105181-06-4 20mg QQ客服：215959384
    存储与注意事项
    1. 在您收到产品后请检查产品。如无问题，请将产品存入冰霜并且样品瓶保持密封，产品可以存放长达24个月（2-8摄氏度）。

    2. 只要有可能，产品溶解后，您应该在同一天应用于您的实验。 但是，如果您需要提前做预实验，或者需要全部溶解，我们建议您将溶液以等分试样的形式存放在-20℃的密封小瓶中。 通常，这些可用于长达两周。 使用前，打开样品瓶前，我们建议您将产品平衡至室温至少1小时。

    3. 需要更多关于溶解度，使用和处理的建议？ 请发送电子邮件至：service@chemfaces.com
    订购流程
  • 1. 在线订购
  • 请联系我们QQ客服

  • 2. 电话订购
  • 请拨打电话：
    027-84237683 或 027-84237783

  • 3. 邮件或传真订购
  • 发送电子邮件到: manager@chemfaces.com 或
    发送传真到：027-84254680

    • 提供订购信息
  • 为了方便客户的订购，请需要订购ChemFaces产品的客户，在下单的时候请提供下列信息，以供我们快速为您建立发货信息。
  •  
  • 1. 产品编号（CAS No.或产品名称）
  • 2. 发货地址
  • 3. 联系方法 (联系人，电话）
  • 4. 开票抬头 (如果需要发票的客户）
  • 5. 发票地址（发货地址与发票地址不同）
    • 发货时间
    1. 付款方式为100%预付款客户，我们将在确认收到货款后当天或1-3个工作日发货。

    2. 付款方式为月结的客户，我们承诺在收到订单后当天或1-3个工作日内发货。

    3. 如果客户所需要的产品，需要重新生产，我们有权告知客户，交货时间需要延期。
    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学，并且还在增涨
  • University of Maryland School of Medicine (USA)
  • Uniwersytet Medyczny w ?odzi (Poland)
  • Weizmann Institute of Science (Israel)
  • University of Beira Interior (Portugal)
  • Rio de Janeiro State University (Brazil)
  • University of Otago (New Zealand)
  • The Institute of Cancer Research (United Kingdom)
  • Kyoto University (Japan)
  • University of Hull (United Kingdom)
  • Monash University (Australia)
  • Uniwersytet Gdański (Poland)
  • Universidad de Buenos Aires (Argentina)
  • Mendel University in Brno (Czech Republic)
  • Universidad Miguel Hernández (Spain)
  • More...
    • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Int J Mol Sci.2021, 22(16):8604.
  • J Drug Delivery Science and Tech.2022, 67:102957.
  • Phytomedicine.2024, 125:155350.
  • Acta Pharm Sin B.2024, 14(4):1772-1786.
  • Sci Rep.2023, 13(1):13072.
  • Bioorg Chem.2024, 145:107184.
  • J Mater Chem B.2019, 7(39):5896-5919
  • Antioxidants (Basel).2021, 10(3):379.
  • Current Topics in Nutraceutical Research2021, 19(1),p90-105.
  • Int. J. Mol. Sci.2022, 23(14),7699;
  • Biomed Pharmacother.2023, 163:114785.
  • J of Dentistry & Oral Health2019, 2641-1962
  • Oncol Rep.2016, 35(3):1356-64
  • Sci Rep.2023, 13(1):21690.
  • Mol Biol Rep.2023, 50(5):4029-4038.
  • Cell Rep.2022, 39(1):110643.
  • Applied Biological Chemistry2023, 66:42.
  • Molecules.2018, 23(7):E1817
  • Pharmacogn Mag.2015, 11(43):562-6
  • Int J Mol Sci.2019, 21(1):E265
  • Int Immunopharmacol.2023, 125:111175.
  • J.of Traditional&Complementary Med.2022, 10.1016:j.jtcme.
  • Sains Malaysiana2022, 51(4):1143-1154
  • ...
    • 生物活性
    Description: 9-Oxoageraphorone has strong acaricidal activity against P. cuniculi in vitro, it also exhibits high insecticidal effects.
    In vitro:
    Vet.Parasitol.,2014 Jun 16;203(1-2):197-202.
    Isolation and identification of acaricidal compounds in Eupatorium adenophorum petroleum ether extract and determination of their acaricidal activity against Psoroptes cuniculi.[Pubmed: 24569033 ]

    METHODS AND RESULTS:
    We used multiple silica gel column chromatography and thin-layer chromatography coupled with (1)H nuclear magnetic resonance (NMR) and (13)C NMR to separate and identify the active acaricidal ingredients in Eupatorium adenophorum petroleum ether extract. The acaricidal activity of each compound was tested against Psoroptes cuniculi in vitro. Three compounds had strong acaricidal activity against P. cuniculi in vitro. The insecticidal effect of 0.5% compound 9β-hydroxy-ageraphorone was better than the insecticidal effect of fenvalerate, and compounds 9-Oxoageraphorone and 9-oxo-10,11-dehydro-ageraphorone exhibited higher insecticidal effects than 9β-hydroxy-ageraphorone.
    CONCLUSIONS:
    Thus, the E. adenophorum petroleum ether extract contains an effective composition of acaricides that could potentially be developed as a promising plant-origin acaricide.
    In vivo:
    Nat Prod Bioprospect. 2014 Dec 12.
    Toxicity Assessment of Cadinene Sesquiterpenes from Eupatorium adenophorum in Mice.[Pubmed: 25500813]

    METHODS AND RESULTS:
    We firstly tested median lethal dose (LD50) in mice of three cadinene sesquiterpenes 2-deoxo-2-(acetyloxy)-9-Oxoageraphorone (DAOA), 9-oxoagerophorone (OA) and 9-oxo-10,11-dehydro-agerophorone (ODA) from Eupatorium adenophorum (Ea). DAOA (215-4640 mg/kg BW, given orally) showed lowest LD50 at 926 mg/kg BW for male mice in contrast with 9-oxoagerophorone (1470 mg/kg BW) and ODA (1470 mg/kg BW).
    CONCLUSIONS:
    In sub-acute study, repeated doses (75-300 mg/kg BW, for 7 days) of DAOA/9-oxoagerophorone increased blood parameters, liver and spleen index in dose dependent relationship, along with decrease in thymus index. 75 mg/kg dose of DAOA/9-oxoagerophorone was found to be approximately/totally safe over the span of 7 days treatment showing no change in all above described parameters.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.268 mL 21.3402 mL 42.6803 mL 85.3606 mL 106.7008 mL
    5 mM 0.8536 mL 4.268 mL 8.5361 mL 17.0721 mL 21.3402 mL
    10 mM 0.4268 mL 2.134 mL 4.268 mL 8.5361 mL 10.6701 mL
    50 mM 0.0854 mL 0.4268 mL 0.8536 mL 1.7072 mL 2.134 mL
    100 mM 0.0427 mL 0.2134 mL 0.4268 mL 0.8536 mL 1.067 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    3,8-二氧代-7alpha-羟基-4,11(12)-四去氢杜松烷; 7alpha-Hydroxy-4,11-cadinadiene-3,8-dione CFN96752 1423809-64-6 C15H20O3 = 248.32 5mg QQ客服：2056216494
    10alpha-羟基日本刺参萜-4-酮/刺参酮; Oplopanone CFN99884 1911-78-0 C15H26O2 = 238.4 5mg QQ客服：1457312923
    款冬酮; Tussilagone CFN90629 104012-37-5 C23H34O5 = 390.51 20mg QQ客服：3257982914
    Reneilmol; Reneilmol CFN98296 260968-11-4 C15H28O3 = 256.4 5mg QQ客服：2056216494
    Longiferone B; Longiferone B CFN89084 1639810-67-5 C15H22O = 218.34 5mg QQ客服：215959384
    [2R-(2alpha,4alpha,4abeta,5alpha,7beta,7abeta)]-六氢-4-甲氧基-7a-甲基-8-亚甲基-2,5-甲桥环戊二烯并-1,3-二恶英-7-醇; 1-O-Methyljatamanin D CFN96381 54656-47-2 C11H16O4 = 212.3 5mg QQ客服：3257982914
    Ylangenyl acetate; Ylangenyl acetate CFN96414 90039-63-7 C17H26O2 = 262.39 5mg QQ客服：215959384
    Ylangenol; Ylangenol CFN96415 41610-69-9 C15H24O = 220.35 5mg QQ客服：2056216494
    10(14)-杜松萜烯-4,5-二醇; 10(14)-Cadinene-4,5-diol CFN97146 672336-50-4 C15H26O2 = 238.4 5mg QQ客服：2159513211
    异水菖蒲二醇; Isocalamendiol CFN98278 25330-21-6 C15H26O2 = 238.4 5mg QQ客服：215959384

    信息支持


    公司简介
    订购流程
    付款方式
    退换货政策

    ChemFaces提供的产品仅用于科学研究使用，不用于诊断或治疗程序。

    联系方式


    电机：027-84237783
    传真：027-84254680
    在线QQ: 1413575084
    E-Mail：manager@chemfaces.com

    湖北省武汉沌口经济技术开区车城南路83号1号楼第三层厂房


    ChemFaces为科学家，科研人员与企业提供快速的产品递送。我们通过瑞士SGS ISO 9001:2008质量体系认证天然化合物与对照品的研发和生产。