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  • 3-Oxo-21alpha-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone

    3-Oxo-21alpha-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone

    3-Oxo-21alpha-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone
    产品编号 CFN96722
    CAS编号 1260173-73-6
    分子式 = 分子量 C27H40O4 = 428.61
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Triterpenoids
    植物来源 The stem barks of Aphanamixis grandifolia.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    3-Oxo-21alpha-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone CFN96722 1260173-73-6 1mg QQ客服:1413575084
    3-Oxo-21alpha-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone CFN96722 1260173-73-6 5mg QQ客服:1413575084
    3-Oxo-21alpha-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone CFN96722 1260173-73-6 10mg QQ客服:1413575084
    3-Oxo-21alpha-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone CFN96722 1260173-73-6 20mg QQ客服:1413575084
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Universidade Federal de Goias (UFG) (Brazil)
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  • University of Wisconsin-Madison (USA)
  • University of Mysore (India)
  • Chulalongkorn University (Thailand)
  • University of Amsterdam (Netherlands)
  • Mahatma Gandhi University (India)
  • University of Leipzig (Germany)
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  • Universitas Airlangga (Indonesia)
  • Weizmann Institute of Science (Israel)
  • University of British Columbia (Canada)
  • Cornell University (USA)
  • Donald Danforth Plant Science Center (USA)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Phytother Res.2019, 33(5):1490-1500
  • J Mol Med (Berl).2018, 96(7):661-672
  • Biol Pharm Bull.2017, 40(6):797-806
  • Fitoterapia.2021, 153:104995.
  • Plant Cell Physiol.2023, 64(7):716-728.
  • Korean Journal of Pharmacognosy2018, 49(3):270-277
  • SBRAS2016, 12
  • Phytomedicine.2018, 41:62-66
  • J Control Release.2021, 336:159-168.
  • Lab Chip.2018, 18(6):971-978
  • Korean Journal of Pharmacognosy.2015, 46(4):352-364
  • J Basic Clin Physiol Pharmacol.2016, 27(1):1-8
  • The Japan Society for Analytical Chemistry2017, 613-617
  • Mol Med Rep.2024, 29(2):26.
  • Front Pharmacol.2018, 9:236
  • Int J Mol Sci.2022, 23(11):6104.
  • BMC Pharmacol Toxicol.2018, 19(1):5
  • South African J of Plant&Soil2018, 29-32
  • STAR Protoc.2024, 5(2):102990.
  • Curr Issues Mol Biol.2023, 45(2):1587-1600.
  • Cancer Manag Res.2019, 11:483-500
  • Appl Biochem Biotechnol.2020, 190(2):732-744
  • J Sci Food Agric.2022, 102(4):1628-1639
  • ...
  • 生物活性
    Description: 3-Oxo-21alpha-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone may show cytotoxic activities against five tumor cell lines (MCF-7, HeLa, HepG2, SGC-7901 and BGC-823).
    In vitro:
    Phytochemistry. 2010 Dec;71(17-18):2199-204.
    Cytotoxic tirucallane C26 triterpenoids from the stem barks of Aphanamixis grandifolia.[Pubmed: 20851441 ]

    METHODS AND RESULTS:
    Five tirucallane type C(26) triterpenoids, accompanied by two known compounds, 3α-hydroxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone and 3-oxo-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone, were isolated from the stem barks of Aphanamixis grandifolia. Their structures were established mainly by means of a combination of 1D and 2D NMR spectroscopic and mass spectrometry techniques as 3α-hydroxyl-21α-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone, 3α-hydroxy-21β-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone,3-Oxo-21alpha-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone, 3-oxo-21β-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone, and 3-oxo-21α-ethoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone.
    CONCLUSIONS:
    All isolates were in vitro evaluated for their cytotoxic activities against five tumor cell lines (MCF-7, HeLa, HepG2, SGC-7901 and BGC-823).
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.3331 mL 11.6656 mL 23.3312 mL 46.6625 mL 58.3281 mL
    5 mM 0.4666 mL 2.3331 mL 4.6662 mL 9.3325 mL 11.6656 mL
    10 mM 0.2333 mL 1.1666 mL 2.3331 mL 4.6662 mL 5.8328 mL
    50 mM 0.0467 mL 0.2333 mL 0.4666 mL 0.9332 mL 1.1666 mL
    100 mM 0.0233 mL 0.1167 mL 0.2333 mL 0.4666 mL 0.5833 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    Odoratone; Odoratone CFN99807 16962-90-6 C30H48O4 = 472.7 5mg QQ客服:3257982914
    Bourjotinolone A; Bourjotinolone A CFN97185 6985-35-9 C30H48O4 = 472.7 5mg QQ客服:2056216494
    鬃毛酮; Hispidone CFN97222 73891-72-2 C30H48O4 = 472.7 5mg QQ客服:2159513211
    3-氧代-24,25,26,27-四去甲甘遂-7-烯-23(21)-内酯; 3-Oxo-24,25,26,27-tetranortirucall-7-en-23,21-olide CFN97318 828935-47-3 C26H38O3 = 398.6 5mg QQ客服:1413575084
    3-Oxo-21alpha-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone; 3-Oxo-21alpha-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone CFN96722 1260173-73-6 C27H40O4 = 428.61 5mg QQ客服:1413575084
    Laxiracemosin H ; Laxiracemosin H CFN96601 1241871-28-2 C26H35NO3 = 409.57 5mg QQ客服:1413575084
    苦楝萜酮内酯; Kulactone CFN92976 22611-36-5 C30H44O3 = 452.67 5mg QQ客服:2056216494
    3-Epimeliasenin B; 3-Epimeliasenin B CFN97842 1222475-77-5 C30H44O4 = 468.68 5mg QQ客服:1413575084
    Meliasenin B; Meliasenin B CFN99339 1221262-77-6 C30H44O4 = 468.7 5mg QQ客服:2056216494
    Sendanolactone; Sendanolactone CFN97113 64929-59-5 C30H42O4 = 466.7 5mg QQ客服:215959384

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