3',8-二羟基驴食草酚

3',8-Dihydroxyvestitol

	产品编号	CFN95384
	CAS编号	122587-87-5
	分子式 = 分子量	C₁₆H₁₆O₆ = 304.3
	产品纯度	>=98%
	物理属性	Powder
	化合物类型	Flavonoids
	植物来源	The herbs of Lotus corniculatus L.
ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用

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产品名称	产品编号	CAS编号	包装	QQ客服
3',8-二羟基驴食草酚	CFN95384	122587-87-5	1mg	QQ客服：2159513211
3',8-二羟基驴食草酚	CFN95384	122587-87-5	5mg	QQ客服：2159513211
3',8-二羟基驴食草酚	CFN95384	122587-87-5	10mg	QQ客服：2159513211
3',8-二羟基驴食草酚	CFN95384	122587-87-5	20mg	QQ客服：2159513211

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ChemFaces的产品在许多优秀和顶级科学期刊中被引用

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089

Universidade Federal de Pernambuco (UFPE) (Brazil)

Institute of Pathophysiology Medical University of Vienna (Austria)

University of Queensland (Australia)

National Cancer Center Research Institute (Japan)

Uniwersytet Medyczny w ?odzi (Poland)

University of Beira Interior (Portugal)

Korea Intitute of Science and Technology (KIST) (Korea)

Universidade de Franca (Brazil)

Guangzhou Institutes of Biomedicine and Health (China)

Kyoto University (Japan)

Rio de Janeiro State University (Brazil)

National Research Council of Canada (Canada)

Max Rubner-Institut (MRI) (Germany)

University of East Anglia (United Kingdom)

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Description:

3',8-Dihydroxyvestitol could serve as antiviral drugs for dengue infection.

In vitro:

Bioinformation . 2014 Jul 22;10(7):460-465.

Molecular Docking Based Screening of Plant Flavonoids as Dengue NS1 Inhibitors[Pubmed: 25187688]

Dengue infection has turned into a serious health concern globally due to its high morbidity rate and a high possibility of increase in its mortality rate on the account of unavailability of any proper treatment for severe dengue infection. The situation demands an urgent development of efficient and practicable treatment to deal with Dengue virus (DENV). Flavonoids, a class of phytochemicals present in medicinal plants, possess anti-viral activity and can be strong drug candidates against viruses. NS1 glycoprotein of Dengue virus is involved in its RNA replication and can be a strong target for screening of drugs against this virus. Current study focuses on the identification of flavonoids which can block Asn-130 glycosylation site of Dengue virus NS1 to inhibit viral replication as glycosylation of NS1 is required for its biological functioning. Molecular docking approach was used in this study and the results revealed that flavonoids have strong potential interactions with active site of NS1. Six flavonoids (Deoxycalyxin A; 3,5,7,3',4'-pentahydroxyflavonol-3-O-beta-D-galactopyranoside; (3R)-3',8-Dihydroxyvestitol; Sanggenon O; Epigallocatechin gallate; Chamaejasmin) blocked the Asn-130 glycosylation site of NS1 and could be able to inhibit the viral replication. It can be concluded from this study that these flavonoids could serve as antiviral drugs for dengue infections. Further in-vitro analyses are required to confirm their efficacy and to evaluate their drug potency.

产品名称	产品编号	CAS编号	分子式 = 分子量	位单	联系QQ
降香黄烃; Odoriflavene	CFN91023	101153-41-7	C₁₇H₁₆O₅ = 300.31	5mg	QQ客服：2159513211
Bidwillol A; Bidwillol A	CFN97992	161099-42-9	C₂₁H₂₂O₄ = 338.4	5mg	QQ客服：2159513211
Erythbidin A; Erythbidin A	CFN96547	210050-83-2	C₂₀H₂₀O₄ = 324.37	5mg	QQ客服：2159513211
光果甘草素; Glabrene	CFN96402	60008-03-9	C₂₀H₁₈O₄ = 322.4	5mg	QQ客服：215959384
Dehydroglyasperin C; Dehydroglyasperin C	CFN96483	199331-35-6	C₂₁H₂₂O₅ = 354.4	5mg	QQ客服：1413575084
粗毛甘草素C; Glyasperin C	CFN95065	142474-53-1	C₂₁H₂₄O₅ = 356.4	5mg	QQ客服：1413575084
甘草西定; Licoricidin	CFN96389	30508-27-1	C₂₆H₃₂O₅ = 424.5	5mg	QQ客服：1413575084
甘草异黄烷甲; Licorisoflavan A	CFN96372	129314-37-0	C₂₇H₃₄O₅ = 438.6	5mg	QQ客服：1413575084
脱氢雌马酚; Phenoxodiol	CFN91578	81267-65-4	C₁₅H₁₂O₃ = 240.3	5mg	QQ客服：1457312923
去甲基驴食草酚; Demethylvestitol	CFN96183	65332-45-8	C₁₅H₁₄O₄ = 258.3	5mg	QQ客服：1457312923

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	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.2862 mL	16.4312 mL	32.8623 mL	65.7246 mL	82.1558 mL
5 mM	0.6572 mL	3.2862 mL	6.5725 mL	13.1449 mL	16.4312 mL
10 mM	0.3286 mL	1.6431 mL	3.2862 mL	6.5725 mL	8.2156 mL
50 mM	0.0657 mL	0.3286 mL	0.6572 mL	1.3145 mL	1.6431 mL
100 mM	0.0329 mL	0.1643 mL	0.3286 mL	0.6572 mL	0.8216 mL