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  • 3',3'''-二柚皮素

    3',3'''-Binaringenin

    3',3'''-二柚皮素
    产品编号 CFN95558
    CAS编号 145399-99-1
    分子式 = 分子量 C30H22O10 = 542.5
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Flavonoids
    植物来源 The herbs of Selaginella uncinata
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    3',3'''-二柚皮素 CFN95558 145399-99-1 1mg QQ客服:1457312923
    3',3'''-二柚皮素 CFN95558 145399-99-1 5mg QQ客服:1457312923
    3',3'''-二柚皮素 CFN95558 145399-99-1 10mg QQ客服:1457312923
    3',3'''-二柚皮素 CFN95558 145399-99-1 20mg QQ客服:1457312923
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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  • The Vancouver Prostate Centre (VPC) (Canada)
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  • Wroclaw Medical University (Poland)
  • Lodz University of Technology (Poland)
  • University of Liège (Belgium)
  • University of Eastern Finland (Finland)
  • Donald Danforth Plant Science Center (USA)
  • Universita' Degli Studi Di Cagliari (Italy)
  • Universidad de La Salle (Mexico)
  • Universiti Sains Malaysia (Malaysia)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • APMIS.2019, 127(10):688-695
  • Asian Pac J Cancer Prev.2021, 22(S1):97-106.
  • Nutrients.2023, 15(12):2810.
  • Food Chem.2022, 373(Pt B):131364.
  • Nutrients.2023, 15(12):2644.
  • Plos One.2020, 10.1371
  • Research SPJ.2024, 0377.
  • Evid Based Complement Alternat Med.2020, 2020:8582318.
  • Synthetic and Systems Biotechnology2023, j.synbio.
  • J Cell Mol Med.2023, 27(10):1423-1435.
  • J Cell Mol Med.2023, jcmm.18071.
  • International Food Research Journal2018, 25(6):2560-2571
  • Heliyon.2023, 9:e21652.
  • Biology (Basel).2020, 9(11):363.
  • J Clin Med.2019, 8(10):E1664
  • Front Nutr.2023, 10:1168095.
  • Phytochem Anal.2016, 27(5):296-303
  • Molecules.2024, 29(5):1171.
  • Pharm Biol.2017, 55(1):360-366
  • BMC Plant Biol.2021, 21(1):60.
  • J. of The Korean Society of Food Culture2017, 144-149
  • Toxins (Basel).2019, 11(10):E575
  • Nat Prod Sci.2019, 25(3):238
  • ...
  • 生物活性
    Description: 3',3'''-Binaringenin has antitumor activity.
    In vivo:
    Front Pharmacol . 2022 Apr 29;13:849110.
    Tissue Distribution, Excretion, and Interaction With Human Serum Albumin of Total Bioflavonoid Extract From Selaginella doederleinii[Pubmed: 35571075]
    Selaginella doederleinii Hieron is a traditional Chinese medicinal herb widely used to treat different cancers. Previously, we showed that the total bioflavonoid extract of S. doederleinii (TBESD) exhibits anti-carcinogenic activities both in vitro and in vivo. However, the plasma protein binding and pharmacokinetics parameters of TBESD remain unclear. To investigate plasma protein binding, tissue distribution, and excretion of TBESD, rats were administered a single dose of TBESD (600 mg/kg) intragastrically and tissue distribution and excretion of TBESD components were determined by rapid high-performance liquid chromatography and tandem mass spectrometry. TBESD binding to human serum albumin (HSA) was assessed by fluorescence spectroscopy. TBESD components amentoflavone, delicaflavone, robustaflavone, 2″,3″-dihydro-3',3‴-biapigenin, and 3',3‴-binaringenin were rapidly absorbed and distributed in various tissues, mostly in the lungs, kidneys, and ovaries, without long-term accumulation. The excretion of bioflavonoids occurred mostly via the intestinal tract and constituted 30% of the administered dose up to 48 h. Spectral analysis indicated that TBESD had a dynamic quenching effect on HSA by binding to one HSA site through hydrophobic interactions and hydrogen bond formation. This is the first comprehensive report on the tissue distribution, excretion, and plasma protein binding of TBESD. This study provides important information on TBESD pharmacokinetics necessary for its further development into a therapeutic form for clinical applications.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.8433 mL 9.2166 mL 18.4332 mL 36.8664 mL 46.0829 mL
    5 mM 0.3687 mL 1.8433 mL 3.6866 mL 7.3733 mL 9.2166 mL
    10 mM 0.1843 mL 0.9217 mL 1.8433 mL 3.6866 mL 4.6083 mL
    50 mM 0.0369 mL 0.1843 mL 0.3687 mL 0.7373 mL 0.9217 mL
    100 mM 0.0184 mL 0.0922 mL 0.1843 mL 0.3687 mL 0.4608 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    2,3-Dihydroamentoflavone 7,4'-dimethyl ether; 2,3-Dihydroamentoflavone 7,4'-dimethyl ether CFN96163 873999-88-3 C32H24O10 = 568.5 5mg QQ客服:2159513211
    2,3-二羟基三叶橡胶黄酮; 2,3-Dihydroheveaflavone CFN96119 110382-42-8 C33H26O10 = 582.6 5mg QQ客服:2056216494
    2,3-二羟基金松双黄酮; 2,3-dihydrosciadopitysin CFN96134 34421-19-7 C33H26O10 = 582.6 5mg QQ客服:2056216494
    2,3-二氢罗汉松黄酮A; 2,3-Dihydropodocarpusflavone A CFN96378 852875-96-8 C31H22O10 = 554.5 5mg QQ客服:1457312923
    四氢阿曼托黄素; Tetrahydroamentoflavone CFN98755 48236-96-0 C30H22O10 = 542.5 5mg QQ客服:2159513211
    3',3'''-二柚皮素; 3',3'''-Binaringenin CFN95558 145399-99-1 C30H22O10 = 542.5 5mg QQ客服:2159513211
    穗花杉双黄酮; 阿曼托黄酮; Amentoflavone CFN99526 1617-53-4 C30H18O10 = 538.46 20mg QQ客服:2056216494
    7-去甲基银杏双黄酮; Bilobetin CFN98846 521-32-4 C31H20O10 = 552.5 20mg QQ客服:215959384
    红杉双黄酮; Sequoiaflavone CFN95642 21763-71-3 C31H20O10 = 552.5 5mg QQ客服:3257982914
    苏铁双黄酮; Sotetsuflavone CFN93257 2608-21-1 C31H20O10 = 552.5 5mg QQ客服:2159513211

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