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  • 厚朴木酚素A

    Magnolignan A

    厚朴木酚素A
    产品编号 CFN96188
    CAS编号 93673-81-5
    分子式 = 分子量 C18H20O4 = 300.4
    产品纯度 >=98%
    物理属性 Oil
    化合物类型 Lignans
    植物来源 The barks of Magnolia officinalis
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    厚朴木酚素A CFN96188 93673-81-5 1mg QQ客服:1457312923
    厚朴木酚素A CFN96188 93673-81-5 5mg QQ客服:1457312923
    厚朴木酚素A CFN96188 93673-81-5 10mg QQ客服:1457312923
    厚朴木酚素A CFN96188 93673-81-5 20mg QQ客服:1457312923
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Medicine and Pharmacy (Romania)
  • University of Fribourg (Switzerland)
  • Universidad de Ciencias y Artes de Chiapas (Mexico)
  • Biotech R&D Institute (USA)
  • Heidelberg University (Germany)
  • Univerzita Karlova v Praze (Czech Republic)
  • University of the Basque Country (Spain)
  • University of Vienna (Austria)
  • Molecular Biology Institute of Barcelona (IBMB)-CSIC (Spain)
  • University of Otago (New Zealand)
  • The Australian National University (Australia)
  • National Cancer Center Research Institute (Japan)
  • The University of Newcastle (Australia)
  • John Innes Centre (United Kingdom)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Int J Mol Sci.2022, 23(20):12516.
  • Plant Physiol Biochem.2019, 144:355-364
  • Front Microbiol.2021, 12:736780.
  • Phytomedicine.2020, 153440.
  • J Pharm Biomed Anal.2019, 164:119-127
  • Univerzita Karlova2021, 20.500.11956.
  • Korean Journal of Pharmacognosy2014, 113-120
  • J Biol Chem.2021, 297(6):101362.
  • J.Acta Agriculturae Scandinavica2017, 571-575
  • Cell.2022, 185(23):4298-4316.e21.
  • Research Square2021, 10.21203.
  • Journal of Life Science2018, 917-922
  • Korean Journal of Pharmacognosy2018, 49(4):349-361
  • Molecules.2020, 25(21):5087.
  • J Mol Histol.2019, 50(4):343-354
  • Antioxidants (Basel).2022, 11(12):2496.
  • Environ Toxicol.2022, 37(3):514-526.
  • Evid Based Complement Alternat Med.2021, 2021:5023536.
  • Front Plant Sci.2022, 12:811166.
  • Metab Eng.2022, 75:143-152.
  • HortTechnology2016, 26(6):816-819
  • The Journal of Internal Korean Medicine2015, 36(4):486-497
  • Toxins (Basel).2021, 13(12):898.
  • ...
  • 生物活性
    Description: Magnolignan A-2-O-beta-D-glucopyranoside has medium cytotoxic activity against HEp-2 and HepG2 cells, with IC(50) of 13.3 microM, and 46.4 microM, respectively.
    In vitro:
    Magn Reson Chem. 2008 May;46(5):497-500.
    1H and 13C NMR assignments for two lignans from the heartwood of Streblus asper.[Pubmed: 18297743 ]

    METHODS AND RESULTS:
    In our ongoing investigation of the bioactive constituents from plants, two new lignans, magnolignan A-2-O-beta-D-glucopyranoside and strebluslignanol were isolated from heartwood of Streblus asper, along with three known lignans, magnolignan A, magnolol, and magnaldehyde D. 1D and 2D NMR experiments, including COSY, HMQC, and HMBC, and other spectroscopic methods, including UV, IR, and MS were used for the determination of the structures and NMR assignments.
    CONCLUSIONS:
    Primary bioassays showed that magnolignan A-2-O-beta-D-glucopyranoside and strebluslignanol have medium cytotoxic activity against HEp-2 and HepG2 cells, with IC(50) of 13.3 microM, 46.4 microM and 10.1 microM, 21.7 microM, respectively.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.3289 mL 16.6445 mL 33.2889 mL 66.5779 mL 83.2224 mL
    5 mM 0.6658 mL 3.3289 mL 6.6578 mL 13.3156 mL 16.6445 mL
    10 mM 0.3329 mL 1.6644 mL 3.3289 mL 6.6578 mL 8.3222 mL
    50 mM 0.0666 mL 0.3329 mL 0.6658 mL 1.3316 mL 1.6644 mL
    100 mM 0.0333 mL 0.1664 mL 0.3329 mL 0.6658 mL 0.8322 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    (1S,2S)-threo-Honokitriol; (1S,2S)-threo-Honokitriol CFN95076 1099687-80-5 C18H20O5 = 316.4 5mg QQ客服:215959384
    厚朴醛B; Magnaldehyde B CFN95075 92829-72-6 C18H16O3 = 280.3 5mg QQ客服:1457312923
    厚朴醛D; Magnaldehyde D CFN96172 93753-33-4 C16H14O3 = 254.3 5mg QQ客服:2159513211
    四氢厚朴酚; Tetrahydromagnolol CFN91033 20601-85-8 C18H22O2 = 270.4 20mg QQ客服:2056216494
    厚朴酚; Magnolol CFN98872 528-43-8 C18H18O2 = 266.3 20mg QQ客服:2056216494
    和厚朴酚; Honokiol CFN99902 35354-74-6 C18H18O2 = 266.34 20mg QQ客服:3257982914
    4'-O-甲基和厚朴酚; 4'-O-Methylhonokiol CFN91498 68592-15-4 C19H20O2 = 280.4 5mg QQ客服:2159513211
    2-O-甲基和厚朴酚; 2-O-Methylhonokiol CFN91499 68592-19-8 C19H20O2 = 280.4 5mg QQ客服:215959384
    2,4'-O-二甲基和厚朴酚; Di-O-methylhonokiol CFN91500 68592-18-7 C20H22O2 = 294.4 5mg QQ客服:1413575084
    异红花八角醇; Isodunnianol CFN99449 139726-30-0 C27H26O3 = 398.5 5mg QQ客服:215959384

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