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  • 厚朴木酚素A

    Magnolignan A

    厚朴木酚素A
    产品编号 CFN96188
    CAS编号 93673-81-5
    分子式 = 分子量 C18H20O4 = 300.4
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Lignans
    植物来源 The barks of Magnolia officinalis
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    厚朴木酚素A CFN96188 93673-81-5 1mg QQ客服:215959384
    厚朴木酚素A CFN96188 93673-81-5 5mg QQ客服:215959384
    厚朴木酚素A CFN96188 93673-81-5 10mg QQ客服:215959384
    厚朴木酚素A CFN96188 93673-81-5 20mg QQ客服:215959384
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • The Institute of Cancer Research (United Kingdom)
  • University of Stirling (United Kingdom)
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  • Korea Institute of Oriental Medicine (Korea)
  • Helmholtz Zentrum München (Germany)
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  • University of Otago (New Zealand)
  • Cornell University (USA)
  • University of Queensland (Australia)
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  • Universidade Católica Portuguesa (Portugal)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Int J Mol Sci. 2014, 15(5):8443-57
  • Mol Med Rep.2015, 12(5):7789-95
  • Int J Mol Med.2015, 35(5):1237-45
  • J Pharm Anal.2016, 6(6):363-373
  • Food Chem.2017, 228:301-314
  • JPC-Journal of Planar Chromatography 2017, 30(4)
  • The Japan Society for Analy. Chem.2017, 66(8):613-617
  • Oncotarget.2017, 8(53):90925-90947
  • Nutrients.2018, 10(12)
  • Int J Mol Sci.2018, 19(2)
  • Molecules.2018, 23(11):E2837
  • Nat Prod Sci.2018, 24(3):206
  • Asian Journal of Chemistry2018, 30(12):2699-2703
  • Korean J Environ Agric.2018, 37(4):260-267
  • J of the Korean Society of Cosmetics and Cosmetology2018, 399-406
  • The Journal of Agromedicine and Medical Sciences2018, 4(1)
  • Sci Adv.2018, 4(10)
  • J Sep Sci.2018, 41(11):2488-2497
  • Nat Commun.2019, 10(1):5169
  • Chemistry of Plant Raw Materials2019, 4:135-147
  • Korean J of Crop Science2019, 452-458
  • TCI CO.2019, US20190151281A1
  • Molecules.2020, 25(3):734
  • ...
  • 生物活性
    Description: Magnolignan A-2-O-beta-D-glucopyranoside has medium cytotoxic activity against HEp-2 and HepG2 cells, with IC(50) of 13.3 microM, and 46.4 microM, respectively.
    In vitro:
    Magn Reson Chem. 2008 May;46(5):497-500.
    1H and 13C NMR assignments for two lignans from the heartwood of Streblus asper.[Pubmed: 18297743 ]

    METHODS AND RESULTS:
    In our ongoing investigation of the bioactive constituents from plants, two new lignans, magnolignan A-2-O-beta-D-glucopyranoside and strebluslignanol were isolated from heartwood of Streblus asper, along with three known lignans, magnolignan A, magnolol, and magnaldehyde D. 1D and 2D NMR experiments, including COSY, HMQC, and HMBC, and other spectroscopic methods, including UV, IR, and MS were used for the determination of the structures and NMR assignments.
    CONCLUSIONS:
    Primary bioassays showed that magnolignan A-2-O-beta-D-glucopyranoside and strebluslignanol have medium cytotoxic activity against HEp-2 and HepG2 cells, with IC(50) of 13.3 microM, 46.4 microM and 10.1 microM, 21.7 microM, respectively.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.3289 mL 16.6445 mL 33.2889 mL 66.5779 mL 83.2224 mL
    5 mM 0.6658 mL 3.3289 mL 6.6578 mL 13.3156 mL 16.6445 mL
    10 mM 0.3329 mL 1.6644 mL 3.3289 mL 6.6578 mL 8.3222 mL
    50 mM 0.0666 mL 0.3329 mL 0.6658 mL 1.3316 mL 1.6644 mL
    100 mM 0.0333 mL 0.1664 mL 0.3329 mL 0.6658 mL 0.8322 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    和厚朴酚; Honokiol CFN99902 35354-74-6 C18H18O2 = 266.34 20mg QQ客服:2932563308
    异红花八角醇; Isodunnianol CFN99449 139726-30-0 C27H26O3 = 398.5 5mg QQ客服:1148253675
    红花八角醇; Dunnianol CFN99448 139726-29-7 C27H26O3 = 398.5 5mg QQ客服:1413575084
    Simonsinol; Simonsinol CFN99661 155709-40-3 C27H26O3 = 398.5 5mg QQ客服:2159513211
    木兰素; Magnolianin CFN96079 147663-91-0 C54H50O8 = 827.0 5mg QQ客服:215959384
    厚朴木酚素A; Magnolignan A CFN96188 93673-81-5 C18H20O4 = 300.4 5mg QQ客服:1413575084
    厚朴木酚素C; Magnolignan C CFN96189 93697-42-8 C18H20O4 = 300.4 5mg QQ客服:2932563308
    (1S,2S)-threo-Honokitriol; (1S,2S)-threo-Honokitriol CFN95076 1099687-80-5 C18H20O5 = 316.4 5mg QQ客服:2159513211
    厚朴醛B; Magnaldehyde B CFN95075 92829-72-6 C18H16O3 = 280.3 5mg QQ客服:2932563308
    厚朴醛D; Magnaldehyde D CFN96172 93753-33-4 C16H14O3 = 254.3 5mg QQ客服:2159513211

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