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  • 厚朴醛D

    Magnaldehyde D

    厚朴醛D
    产品编号 CFN96172
    CAS编号 93753-33-4
    分子式 = 分子量 C16H14O3 = 254.3
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Lignans
    植物来源 The barks of Magnolia officinalis
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    厚朴醛D CFN96172 93753-33-4 1mg QQ客服:215959384
    厚朴醛D CFN96172 93753-33-4 5mg QQ客服:215959384
    厚朴醛D CFN96172 93753-33-4 10mg QQ客服:215959384
    厚朴醛D CFN96172 93753-33-4 20mg QQ客服:215959384
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Universidad Industrial de Santander (Colombia)
  • Universiti Kebangsaan Malaysia (Malaysia)
  • Monash University (Australia)
  • Vin?a Institute of Nuclear Sciences (Serbia)
  • University of Helsinki (Finland)
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  • Universidade do Porto (Portugal)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Molecules.2016, 21(6)
  • Acta Pharmaceutica Hungarica2016, 86:35-40
  • J Ethnopharmacol.2017, 198:87-90
  • Hum Exp Toxicol.2017, 36(11):1169-1176
  • Aquaculture2017, 481:94-102
  • Sci Rep.2017, 7(1):3249
  • Oncotarget.2017, 8(53):90925-90947
  • Nutrients.2018, 10(12):E1998
  • Phytochemistry2018, 15:83-92
  • Korean J of Medicinal Crop Science2018, 220-226
  • Molecules.2018, 23(11):E2837
  • Phytomedicine.2018, 40:37-47
  • Front Plant Sci.2018, 9:1424
  • J Adv Res.2019, 17:85-94
  • Int J Mol Sci.2019, 20(21):E5488
  • Molecules.2019, 24(19):E3417
  • Chin J Appl. Physiol.2019, 35(3):283-288
  • The Malaysian journal of pathology2019, 41(3):243-251
  • Phytomedicine.2019, 65:153089
  • Br J Pharmacol.2020, 10.1111
  • Biomedicine & Pharmacotherapy2020, 125:109950
  • Industrial Crops and Products2020, 146:112186
  • United States Patent Application2020, 20200038363
  • ...
  • 生物活性
    Description: Magnaldehyde D is a natural product from Magnolia officinalis.
    In vitro:
    Planta Medica, 2011 , 77 (12):PG42.
    New biphenyl derivatives and anti-inflammatory constituents from the stem bark of Magnolia officinalis[Reference: WebLink]
    The stem bark of Magnolia officinalis Rehd. et Wils. (Magnoliaceae) has been used as a traditional medicine for the treatment of gastrointestinal disorders, bronchitis, and emphysema, in China, Taiwan, Japan, and Korea [1]. Chemical studies have revealed a variety of neo-lignans and alkaloids as constituents of this plant. Many of these compounds exhibit central depressant effect, muscle relaxation, and antigastric ulcer, antibacterial, antiallergic, vasorelaxant, and neurotrophic activities.
    METHODS AND RESULTS:
    Investigation on EtOAc-soluble fraction of the stem bark of M. officinalis has led to the isolation of three new biphenyls, 5-allyl-5'-(1-hydroxyallyloxy)biphenyl-2,2-diol (1), 5,5'-diallyl-2'-(allyloxy)biphenyl-2-ol (2), and 5,5'-diallyl-2'-(3-methylbut-2-enyloxy)biphenyl-2-ol (3), together with 12 known compounds, including four neolignans, magnolol (4), honokiol (5), (-)-monoterpenylmagnolol (6), and randainal (7), two norlignans, Magnaldehyde D (8) and randaiol (9), and six steroids, β-sitostenone (10), stigmasta-4,22-dien-3-one (11), β-sitosterol (12), stigmasterol (13), 3β-hydroxystigmast-5-en-7-one (14), and 3β-hydroxystigmasta-5,22-dien-7-one (15).
    CONCLUSIONS:
    The structure of new compounds (1-3) were determined through spectroscopic and MS analyses. Among the isolates, magnolol (4) and honokiol (5) exhibited potent inhibition against fMLP-induced superoxide production with IC50 values of 4.42±0.24 and 0.68±0.20μg/mL, respectively. In addition, magnolol (4) inhibited fMLP/CB-induced elastase release with an IC50 values of 1.45±0.20μg/mL.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.9324 mL 19.6618 mL 39.3236 mL 78.6473 mL 98.3091 mL
    5 mM 0.7865 mL 3.9324 mL 7.8647 mL 15.7295 mL 19.6618 mL
    10 mM 0.3932 mL 1.9662 mL 3.9324 mL 7.8647 mL 9.8309 mL
    50 mM 0.0786 mL 0.3932 mL 0.7865 mL 1.5729 mL 1.9662 mL
    100 mM 0.0393 mL 0.1966 mL 0.3932 mL 0.7865 mL 0.9831 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    厚朴木酚素A; Magnolignan A CFN96188 93673-81-5 C18H20O4 = 300.4 5mg QQ客服:1148253675
    厚朴木酚素C; Magnolignan C CFN96189 93697-42-8 C18H20O4 = 300.4 5mg QQ客服:3257982914
    (1S,2S)-threo-Honokitriol; (1S,2S)-threo-Honokitriol CFN95076 1099687-80-5 C18H20O5 = 316.4 5mg QQ客服:1148253675
    厚朴醛B; Magnaldehyde B CFN95075 92829-72-6 C18H16O3 = 280.3 5mg QQ客服:215959384
    厚朴醛D; Magnaldehyde D CFN96172 93753-33-4 C16H14O3 = 254.3 5mg QQ客服:2159513211
    四氢厚朴酚; Tetrahydromagnolol CFN91033 20601-85-8 C18H22O2 = 270.4 20mg QQ客服:215959384
    厚朴酚; Magnolol CFN98872 528-43-8 C18H18O2 = 266.3 20mg QQ客服:2932563308
    和厚朴酚; Honokiol CFN99902 35354-74-6 C18H18O2 = 266.34 20mg QQ客服:1148253675
    异红花八角醇; Isodunnianol CFN99449 139726-30-0 C27H26O3 = 398.5 5mg QQ客服:215959384
    红花八角醇; Dunnianol CFN99448 139726-29-7 C27H26O3 = 398.5 5mg QQ客服:2159513211

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