• 中药标准品生产商,产品定制服务
  • 芹糖甘草苷

    Liquiritin apioside

    芹糖甘草苷
    产品编号 CFN90707
    CAS编号 199796-12-8
    分子式 = 分子量 C26H30O13 = 550.5
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Flavonoids
    植物来源 The roots of Glycyrrhiza uralensis Fisch
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    芹糖甘草苷 CFN90707 199796-12-8 10mg QQ客服:2932563308
    芹糖甘草苷 CFN90707 199796-12-8 20mg QQ客服:2932563308
    芹糖甘草苷 CFN90707 199796-12-8 50mg QQ客服:2932563308
    芹糖甘草苷 CFN90707 199796-12-8 100mg QQ客服:2932563308
    存储与注意事项
    1. 在您收到产品后请检查产品。如无问题,请将产品存入冰霜并且样品瓶保持密封,产品可以存放长达24个月(2-8摄氏度)。

    2. 只要有可能,产品溶解后,您应该在同一天应用于您的实验。 但是,如果您需要提前做预实验,或者需要全部溶解,我们建议您将溶液以等分试样的形式存放在-20℃的密封小瓶中。 通常,这些可用于长达两周。 使用前,打开样品瓶前,我们建议您将产品平衡至室温至少1小时。

    3. 需要更多关于溶解度,使用和处理的建议? 请发送电子邮件至:service@chemfaces.com
    订购流程
  • 1. 在线订购
  • 请联系我们QQ客服

  • 2. 电话订购
  • 请拨打电话:
    027-84237683 或 027-84237783

  • 3. 邮件或传真订购
  • 发送电子邮件到: manager@chemfaces.com 或
    发送传真到:027-84254680

  • 提供订购信息
  • 为了方便客户的订购,请需要订购ChemFaces产品的客户,在下单的时候请提供下列信息,以供我们快速为您建立发货信息。
  •  
  • 1. 产品编号(CAS No.或产品名称)
  • 2. 发货地址
  • 3. 联系方法 (联系人,电话)
  • 4. 开票抬头 (如果需要发票的客户)
  • 5. 发票地址(发货地址与发票地址不同)
  • 发货时间
    1. 付款方式为100%预付款客户,我们将在确认收到货款后当天或1-3个工作日发货。

    2. 付款方式为月结的客户,我们承诺在收到订单后当天或1-3个工作日内发货。

    3. 如果客户所需要的产品,需要重新生产,我们有权告知客户,交货时间需要延期。
    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Indian Institute of Science (India)
  • Molecular Biology Institute of Barcelona (IBMB)-CSIC (Spain)
  • Univerzita Karlova v Praze (Czech Republic)
  • University of Madras (India)
  • Seoul National University of Science and Technology (Korea)
  • Universitas Airlangga (Indonesia)
  • University of British Columbia (Canada)
  • Hamdard University (India)
  • Osmania University (India)
  • Sanford Burnham Prebys Medical Discovery Institute (USA)
  • University of Bonn (Germany)
  • Worcester Polytechnic Institute (USA)
  • University of Malaya (Malaysia)
  • Universidad de Buenos Aires (Argentina)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Phytochem Anal.2013, 24(5):493-503
  • BMC Complement Altern Med.2014, 14:242
  • Mol Med Rep.2015, 12(5):7789-95
  • Sci. Rep.2015, 14-23
  • Industrial Food Engineering2015, 19(4):408-413
  • Molecules.2015, 20(11):20014-30
  • Molecules.2016, 21(6)
  • Nutrients.2017, 10(1)
  • Food Chem.2017, 221:1135-1144
  • Invest New Drugs.2017, 35(2):166-179
  • The Japan Society for Analy. Chem.2017, 66(8):613-617
  • Oncotarget.2017, 8(53):90925-90947
  • Phytochemistry2018, 15:83-92
  • Exp Parasitol.2018, 194:67-78
  • Korean Journal of Pharmacognosy2018, 49(1):76-83
  • Planta Med.2018, 84(6-07):465-474
  • Journal of Life Science2018, 917-922
  • Int J Mol Sci.2019, 20(11):E2734
  • Molecules.2019, 24(19):E3417
  • Journal of Apiculture2019, 34(2):131-136
  • Chemistry of Plant Raw Materials2019, 4:135-147
  • Pest Manag Sci.2019, 75(9):2530-2541
  • TCI CO.2019, US20190151257A1
  • ...
  • 生物活性
    Description: Liquiritin apioside has antioxidant property by inducing glutathione (GSH) biosynthesis via the inhibition of cytokines and protected lung epithelial cells against cigarette smoke-mediated oxidative stress, might be as protective agent against epithelial injury in COPD.
    Targets: TNF-α | TGF-β/Smad
    In vivo:
    Fundam Clin Pharmacol. 2012 Aug;26(4):473-83.
    Protective effects of liquiritin apioside on cigarette smoke-induced lung epithelial cell injury. [Pubmed: 21631586]
    Cigarette smoking is associated with an increased incidence of chronic obstructive pulmonary disease (COPD).
    METHODS AND RESULTS:
    In this study, we hypothesized that liquiritin apioside (LA), a main flavonoid component from Glycyrrhiza uralensis, had antioxidant properties by inducing glutathione (GSH) biosynthesis via the inhibition of cytokines and protected lung epithelial cells against cigarette smoke-mediated oxidative stress. A549 cells were treated with cigarette smoke extract (CSE) and/or LA. ICR mice were exposed to cigarette smoke (CS) for four days with increasing exposure time for up to 6 h per day to elicit epithelial cells injury. One hour before smoke exposure, mice were treated with LA by gavage; 18 h after the last CS exposure all examinations were performed. Treatment with LA concentration-dependently prevented CSE-induced cytotoxicity, increase of TGF-β and TNF-α mRNA expression, depletion of GSH and apoptosis in A549 cells. LA at doses 3, 10 and 30 mg/kg dose-dependently inhibited pulmonary neutrophil and macrophage inflammation. Lung sections of the CS-exposed LA treated mice showed an apparently reduced pulmonary inflammation and a significant inhibitory effect on mucus containing goblet cells in the large airways. Furthermore, the CS-induced pulmonary release of TGF-β, TNF-α and myeloperoxidase activity was reduced, and superoxide dismutase activity was enhanced.
    CONCLUSIONS:
    These results indicate that protective roles of LA on CS-induced the lung epithelial cell injury are mediated by inhibiting TGF-β and TNF-α expression and increasing anti-oxidative levels of GSH, suggesting that LA might be effective as protective agent against epithelial injury in COPD.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.8165 mL 9.0827 mL 18.1653 mL 36.3306 mL 45.4133 mL
    5 mM 0.3633 mL 1.8165 mL 3.6331 mL 7.2661 mL 9.0827 mL
    10 mM 0.1817 mL 0.9083 mL 1.8165 mL 3.6331 mL 4.5413 mL
    50 mM 0.0363 mL 0.1817 mL 0.3633 mL 0.7266 mL 0.9083 mL
    100 mM 0.0182 mL 0.0908 mL 0.1817 mL 0.3633 mL 0.4541 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    异樱花苷; Isosakuranin CFN92809 491-69-0 C22H24O10 = 448.1 10mg QQ客服:215959384
    枸橘苷; Poncirin CFN90448 14941-08-3 C28H34O14 = 594.56 20mg QQ客服:2932563308
    香风草甙; Didymin CFN92363 14259-47-3 C28H34O14 = 594.6 20mg QQ客服:2159513211
    异柚葡糖苷; Isohemiphloin CFN98602 3682-02-8 C21H22O10 = 434.4 5mg QQ客服:2159513211
    杜鹃素 7-O-葡萄糖苷; Farrerol 7-O-glucoside CFN96281 885044-12-2 C23H26O10 = 462.5 5mg QQ客服:2159513211
    Flavaprin; Flavaprin CFN98900 53846-49-4 C26H30O10 = 502.5 5mg QQ客服:1148253675
    甘草苷; Liquiritin CFN99154 551-15-5 C21H22O9 = 418.39 20mg QQ客服:2159513211
    芹糖甘草苷; Liquiritin apioside CFN90707 199796-12-8 C26H30O13 = 550.5 20mg QQ客服:3257982914
    葡萄糖基甘草苷; Glucoliquiritin CFN95011 93446-18-5 C27H32O14 = 580.5 10mg QQ客服:2932563308
    樱桃甙; 洋李甙; Prunin CFN98878 529-55-5 C21H22O10 = 434.4 10mg QQ客服:2932563308

    信息支持


    公司简介
    订购流程
    付款方式
    退换货政策

    ChemFaces提供的产品仅用于科学研究使用,不用于诊断或治疗程序。

    联系方式


    电机:027-84237783
    传真:027-84254680
    在线QQ: 1413575084
    E-Mail:manager@chemfaces.com

    湖北省武汉沌口经济技术开区车城南路83号1号楼第三层厂房


    ChemFaces为科学家,科研人员与企业提供快速的产品递送。我们通过瑞士SGS ISO 9001:2008质量体系认证天然化合物与对照品的研发和生产