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  • 冬青苷D

    Ilexoside D

    冬青苷D
    产品编号 CFN90993
    CAS编号 109008-27-7
    分子式 = 分子量 C41H66O13 = 766.97
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Triterpenoids
    植物来源 The roots of Ilex pubescens Hook. et Arn.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    冬青苷D CFN90993 109008-27-7 1mg QQ客服:215959384
    冬青苷D CFN90993 109008-27-7 5mg QQ客服:215959384
    冬青苷D CFN90993 109008-27-7 10mg QQ客服:215959384
    冬青苷D CFN90993 109008-27-7 20mg QQ客服:215959384
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • The Korea Society of Pha.2014, 300-314
  • Nat Prod Commun.2014, 9(5):679-82
  • ARPN Journal of Eng.& Applied Sci.2016, 2199-2204
  • Braz J Med Biol Res. 2016, 49(7)
  • Mol Immunol. 2016, 78:121-132
  • African J. Agricultural Research 2017, 12(13):1164-1168
  • J. of The Korean Society of Food Culture2017, 144-149
  • Pharmacol Rep.2017, 69(6):1224-1231
  • J Nat Med.2017, 71(4):745-756
  • Food Res Int.2017, 96:40-45
  • Pharmacognosy Magazine2018, 14(56):418-424
  • Int J Mol Sci.2018, 19(9):E2528
  • Evid Based Complement Alternat Med.2018, 2018:4259603
  • J Sep Sci.2018, 41(9):1938-1946
  • J Agric Food Chem.2018, 66(1):351-358
  • Sci Rep.2018, 8:9267
  • Neuropharmacology2019, 151437
  • Int J Mol Sci.2019, 20(14):E3538
  • Molecules.2019, 24(10):E1926
  • Exp Biol Med (Maywood).2019, 244(16):1463-1474
  • Int J Immunopathol Pharmacol.2019, 33:2058738419857537
  • Environ Toxicol.2019, 34(4):513-520.
  • J Clin Med.2019, 8(10):E1664
  • ...
  • 生物活性
    Description: Ilexoside D has ant-allergic, and anti-coagulant activities, it shows anti-tissue factor activity as well as the antithrombotic activity.
    In vitro:
    Tetrahedron Letters, 1991, 32(29):3535-3538.
    Ilexosides A, B, C and D, anti-allergic 18,19-seco-ursane glycosides from fruit of Ilex crenata.[Reference: WebLink]

    METHODS AND RESULTS:
    Four novel 18,19-seco-ursane glycosides named ilexoside A, ilexoside B, ilexoside C and Ilexoside D have been isolated from Ilex crenata Thunb.. Their structures were established as novel glycosides of 3β-hydroxy-19-oxo-18,19-seco-11,13(18)-ursadiene-28-oic-acid on the basis of chemical and spectroscopic analysis.
    CONCLUSIONS:
    They exhibited ant-allergic activities.The ant-alergic effect of Ilexoside A(1) ,ilexoside B(2) ,ilexoside C(3) and Ilexoside D(4) are 10 times as potent as glycyrrhizin.
    In vivo:
    Archives of Pharmacal Research, 1993, 16(3):209-212.
    Anticoagulant activity of ilexoside D, a triterpenoid saponin fromIlex pubescens.[Reference: WebLink]
    The anti-coagulant activity of Ilexoside D isolated from the roots ofIlex pubescens Hook. et Arn. was investigated inin vivo andin vitro models of blood coagulation in rats.
    METHODS AND RESULTS:
    On oral administration, Ilexoside D prolonged the bleeding time and the whole blood recalcified clotting time, but not the plasma recalcified clotting time.In vitro, Ilexoside D did not affect the recalcified clotting times of whole blood, platelet-rich plasma (PRP), and platelet-poor plasma (PPP) while in the presence of tissue factor the compound prolonged the reduced prothrombin times of whole blood, PRP and PPP in the dose-dependent manner.
    CONCLUSIONS:
    These results indicate that Ilexoside D has the anti-tissue factor activity as well as the antithrombotic activity.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.3038 mL 6.5192 mL 13.0383 mL 26.0766 mL 32.5958 mL
    5 mM 0.2608 mL 1.3038 mL 2.6077 mL 5.2153 mL 6.5192 mL
    10 mM 0.1304 mL 0.6519 mL 1.3038 mL 2.6077 mL 3.2596 mL
    50 mM 0.0261 mL 0.1304 mL 0.2608 mL 0.5215 mL 0.6519 mL
    100 mM 0.013 mL 0.0652 mL 0.1304 mL 0.2608 mL 0.326 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    地榆皂苷II; Ziyuglycoside II CFN98465 35286-59-0 C35H56O8 = 604.8 20mg QQ客服:2932563308
    冬青苷D; Ilexoside D CFN90993 109008-27-7 C41H66O13 = 766.97 5mg QQ客服:3257982914
    枸骨叶皂甙I; Ilexside I CFN92273 83725-19-3 C41H66O13 = 472.7 5mg QQ客服:1413575084
    冬青苷K; Ilexoside K CFN90994 109008-26-6 C47H76O18 = 929.10 5mg QQ客服:1413575084
    28-O-beta-D-吡喃葡萄糖果树酸酯; Pomolic acid 28-O-beta-D-glucopyranosyl ester CFN97328 83725-24-0 C36H58O9 = 634.9 5mg QQ客服:3257982914
    刺梨苷 F1; Kaji-ichigoside F1 CFN89311 95298-47-8 C36H58O10 = 650.85 5mg QQ客服:2159513211
    Rosamultin; Rosamultin CFN89097 88515-58-6 C36H58O10 = 650.85 10 mg QQ客服:1413575084
    苦莓苷F1; Niga-ichigoside F1 CFN91060 95262-48-9 C36H58O11 = 666.9 5mg QQ客服:215959384
    山香醇酸糖苷F1; Suavissimoside F1 CFN91067 95645-51-5 C36H56O12 = 680.8 5mg QQ客服:1148253675
    地榆皂苷I; Ziyuglycoside I CFN98464 35286-58-9 C41H66O13 = 767.0 20mg QQ客服:1413575084

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