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  • 刺梨苷 F1

    Kaji-ichigoside F1

    刺梨苷 F1
    产品编号 CFN89311
    CAS编号 95298-47-8
    分子式 = 分子量 C36H58O10 = 650.85
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Triterpenoids
    植物来源 The tuberous roots of Potentilla anserina.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    刺梨苷 F1 CFN89311 95298-47-8 1mg QQ客服:215959384
    刺梨苷 F1 CFN89311 95298-47-8 5mg QQ客服:215959384
    刺梨苷 F1 CFN89311 95298-47-8 10mg QQ客服:215959384
    刺梨苷 F1 CFN89311 95298-47-8 20mg QQ客服:215959384
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Virginia (USA)
  • University of Malaya (Malaysia)
  • The Ohio State University (USA)
  • Leibniz Institute of Plant Biochemistry (Germany)
  • Regional Crop Research Institute (Korea)
  • National Research Council of Canada (Canada)
  • University of Mysore (India)
  • MTT Agrifood Research Finland (Finland)
  • Universidad de La Salle (Mexico)
  • Wroclaw Medical University (Poland)
  • Warszawski Uniwersytet Medyczny (Poland)
  • Funda??o Universitária de Desenvolvimento (Brazil)
  • Universidade da Beira Interior (Germany)
  • University of Illinois at Chicago (USA)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Scientific World Journal.2014, 2014:654193
  • Food Science and Biotechnology2015, 2205-2212
  • University of Limpopo2016, 1-237
  • Phytother Res.2016, 30(12):2020-2026
  • Pharm Biol.2016, 54(7):1255-62
  • Acta Pharmaceutica Hungarica2016, 86:35-40
  • J of L. Chroma.&Related Tech2017, 252-258
  • J Nat Med.2017, 71(4):745-756
  • LWT-Food Science and Technology2017, 75:488-496
  • J Nat Prod.2017, 80(4):854-863
  • Phys Chem Chem Phys.2018, 20(23):15986-15994
  • J Ethnopharmacol.2018, 210:88-94
  • Molecules.2018, 23(2)
  • Cell Biochem Funct.2018, 36(6):303-311
  • J of the Korean Society of Cosmetics and Cosmetology2018, 399-406
  • Cell Death Dis.2019, 10(12):882
  • J Ethnopharmacol.2019, 228:132-141
  • Molecules.2019, 24(2):E343
  • Molecules.2019, 24(4):E709
  • Chin J Appl. Physiol.2019, 35(3):283-288
  • Journal of Functional Foods2019, 52:430-441
  • Molecules.2020, 25(3):734
  • Biochem Biophys Res Commun.2020, 522(4):1052-1058
  • ...
  • 生物活性
    Description: Kaji-ichigoside F1 shows antiinflammatory/antinociceptive action in acetic acid-induced writhing and hot plate testing and in a carrageenan-induced paw edema model in mice and rats. Kaji-ichigoside F1 exhibits in vivo hepatoprotective effects, it inhibited d-GalN-induced cytotoxicity in primary cultured mouse hepatocytes with the IC50 of14.1uM.
    Targets: Immunology & Inflammation related
    In vitro:
    Phytochemistry. 2014 Jun;102:169-81.
    Hepatoprotective triterpenes from traditional Tibetan medicine Potentilla anserina.[Pubmed: 24697904 ]

    METHODS AND RESULTS:
    A methanol extract from the tuberous roots of Potentilla anserina (Rosaceae) exhibited hepatoprotective effects against d-galactosamine (d-GalN)/lipopolysaccharide-induced liver injuries in mice. Six triterpene 28-O-monoglucopyranosyl esters, potentillanosides A-F, were isolated from the extract along with 32 known compounds, including 15 triterpenes. The structures of potentillanosides A-F were determined on the basis of spectroscopic properties and chemical evidence. Four ursane-type triterpene 28-O-monoglycosyl esters, potentillanoside A (IC50=46.7μM), 28-O-β-d-glucopyranosyl pomolic acid (IC50=9.5μM), rosamutin (IC50=35.5μM), and Kaji-ichigoside F1 (IC50=14.1μM), inhibited d-GalN-induced cytotoxicity in primary cultured mouse hepatocytes.
    CONCLUSIONS:
    Among these four triterpenes, potentillanoside A, rosamutin, and Kaji-ichigoside F1 exhibited in vivo hepatoprotective effects at doses of 50-100mg/kg, p.o. The mode of action was ascribable to the reduction in cytotoxicity caused by d-GalN.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.5365 mL 7.6823 mL 15.3645 mL 30.729 mL 38.4113 mL
    5 mM 0.3073 mL 1.5365 mL 3.0729 mL 6.1458 mL 7.6823 mL
    10 mM 0.1536 mL 0.7682 mL 1.5365 mL 3.0729 mL 3.8411 mL
    50 mM 0.0307 mL 0.1536 mL 0.3073 mL 0.6146 mL 0.7682 mL
    100 mM 0.0154 mL 0.0768 mL 0.1536 mL 0.3073 mL 0.3841 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    地榆皂苷II; Ziyuglycoside II CFN98465 35286-59-0 C35H56O8 = 604.8 20mg QQ客服:1148253675
    冬青苷D; Ilexoside D CFN90993 109008-27-7 C41H66O13 = 766.97 5mg QQ客服:1413575084
    枸骨叶皂甙I; Ilexside I CFN92273 83725-19-3 C41H66O13 = 472.7 5mg QQ客服:2932563308
    冬青苷K; Ilexoside K CFN90994 109008-26-6 C47H76O18 = 929.10 5mg QQ客服:2159513211
    28-O-beta-D-吡喃葡萄糖果树酸酯; Pomolic acid 28-O-beta-D-glucopyranosyl ester CFN97328 83725-24-0 C36H58O9 = 634.9 5mg QQ客服:1148253675
    刺梨苷 F1; Kaji-ichigoside F1 CFN89311 95298-47-8 C36H58O10 = 650.85 5mg QQ客服:1413575084
    Rosamultin; Rosamultin CFN89097 88515-58-6 C36H58O10 = 650.85 10 mg QQ客服:1148253675
    苦莓苷F1; Niga-ichigoside F1 CFN91060 95262-48-9 C36H58O11 = 666.9 5mg QQ客服:215959384
    山香醇酸糖苷F1; Suavissimoside F1 CFN91067 95645-51-5 C36H56O12 = 680.8 5mg QQ客服:3257982914
    地榆皂苷I; Ziyuglycoside I CFN98464 35286-58-9 C41H66O13 = 767.0 20mg QQ客服:215959384

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