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  • 胭脂虫酸

    Coccinic acid

    胭脂虫酸
    产品编号 CFN99083
    CAS编号 107783-45-9
    分子式 = 分子量 C30H46O3 = 454.7
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Triterpenoids
    植物来源 The roots of Kadsura coccinea
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    胭脂虫酸 CFN99083 107783-45-9 1mg QQ客服:2159513211
    胭脂虫酸 CFN99083 107783-45-9 5mg QQ客服:2159513211
    胭脂虫酸 CFN99083 107783-45-9 10mg QQ客服:2159513211
    胭脂虫酸 CFN99083 107783-45-9 20mg QQ客服:2159513211
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Dicle (Turkey)
  • Medical University of Gdansk (Poland)
  • Universidad de La Salle (Mexico)
  • University of Queensland (Australia)
  • Kyung Hee University (Korea)
  • University of Pretoria (South Africa)
  • University of Leipzig (Germany)
  • Korea Institute of Oriental Medicine (Korea)
  • Heidelberg University (Germany)
  • University of Melbourne (Australia)
  • Universiti Sains Malaysia (Malaysia)
  • Universiti Putra Malaysia(UPM) (Malaysia)
  • Harvard University (USA)
  • Universita' Degli Studi Di Cagliari (Italy)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • J. of Agricultural Science2015, 1916-9760
  • Phytochemistry Letters2015, 243-247
  • Mol Immunol. 2016, 78:121-132
  • Universidade Estadual Paulista2017, 11449
  • PLoS One.2017, 12(8):e0181191
  • Evid Based Complement Alternat Med.2017, 2017:1583185
  • Naunyn Schmiedebergs Arch Pharmacol.2017, 390(10):1073-1083
  • Industrial Crops and Products2017, 95:286-295
  • Nat Prod Communications2018, 10.1177
  • PLoS One.2018, 13(3):e0193386
  • Nat Chem Biol.2018, 14(8):760-763
  • BMC Pharmacol Toxicol.2018, 19(1):5
  • Evid Based Complement Alternat Med.2018, 2018:3610494
  • Primary and Industrial.2018, 52(11)
  • Chemistry of Plant Materials.2019, 129-136
  • Food and Agriculture Org. Of the UN2019, 151-160
  • BMC Complement Altern Med.2019, 19(1):339
  • Molecules.2019, 24(11):E2044
  • Phytother Res.2019, 33(7):1784-1793
  • Chemistry of Natural Compounds2019, 55(1):127-130
  • Comput Biol Chem.2019, 83:107096
  • LWT-Food Sci Technol2020, 109163
  • Journal of Chromatography A2020, 460942
  • ...
  • 生物活性
    Description: Coccinic acid shows inhibitory effects against colorectal carcinoma HCT-15 and oral epithelial cell line KB-3-1.Mixture of coccinic acid and anwuweizonic acid shows significant inhibitory activity against human decidual cells and rat luteal cells in vitro, suggests that it has antifertility activity.
    Targets: Estrogen receptor | Progestogen receptor
    In vitro:
    Pharm Biol. 2013 Sep;51(9):1204-7.
    Cytotoxic and potential anticancer constituents from the stems of Schisandra pubescens.[Pubmed: 23883077]

    METHODS AND RESULTS:
    Nine known compounds were obtained, including four lignans, epischisandrone (1), tigloylgomisin P (2), cagayanone (3) and (-)-gomisin L₂ (4), together with five triterpenoids, micranoic acid B (5), lancifodilactone H (6), Coccinic acid (7), schisanlactone B (8) and anwuweizonic acid (9).
    CONCLUSIONS:
    Compounds 2-6 and 8 showed moderate to marginal cytotoxicity, with GI₅₀ values of 11.83-35.65 μM.
    Chinese Journal of Modern Applied Pharmacy, 2002, 19(2):103-5.
    Antifertility Triterpenoid Acids from Kadsura angustifolia.[Reference: WebLink]
    To isolate and characterize bioactive compounds from the stems of Kadsura angustifolia .
    METHODS AND RESULTS:
    The compounds were extracted with solvent,isolated by column chromatography and identified by the spectroscopic methods. eight compounds and a mixture of two triterpenoid acids were isolated and identified as epi anwuweizic acid (1),shikimic acid (2),(+) catechin (3),poriferast 5 en 3β,7α diol (4),β sitosterol (5),daucosterol (6),cerotic acid 1 monoglyceride (7) and behenic acid 1 monoglyceride (8),and mixiture of Coccinic acid (9) and anwuweizonic acid (10).
    CONCLUSIONS:
    Mixture of 9 and 10 showed significant inhibitory activity against human decidual cells and rat luteal cells in vitro . Compounds 2~4,7 and 8 were first reported in the family Schisandraceae,and compounds 1,5,6,9 and 10 were isolated from K.angustifolia for the first time.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.1993 mL 10.9963 mL 21.9925 mL 43.985 mL 54.9813 mL
    5 mM 0.4399 mL 2.1993 mL 4.3985 mL 8.797 mL 10.9963 mL
    10 mM 0.2199 mL 1.0996 mL 2.1993 mL 4.3985 mL 5.4981 mL
    50 mM 0.044 mL 0.2199 mL 0.4399 mL 0.8797 mL 1.0996 mL
    100 mM 0.022 mL 0.11 mL 0.2199 mL 0.4399 mL 0.5498 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    安五酸; Anwuweizonic acid CFN92727 117020-59-4 C30H46O3 = 454.7 5mg QQ客服:2159513211
    7-氧代-灵芝酸Z; 7-Oxo-ganoderic acid Z CFN92998 929248-72-6 C30H46O4 = 470.68 5mg QQ客服:215959384
    灵芝酸DM; Ganoderic acid DM CFN99815 173075-45-1 C30H44O4 = 468.7 5mg QQ客服:2159513211
    23S-羟基-11,15-二氧-灵芝酸DM; 23S-hydroxy-11,15-dioxo-ganoderic acid DM CFN80433 1085273-49-9 C30H40O7 = 512.63 5mg QQ客服:3257982914
    灵芝酸Y; Ganoderic acid Y CFN90294 86377-52-8 C30H46O3 = 454.68 5mg QQ客服:215959384
    灵芝酸SZ; Ganoderic acid SZ CFN97426 865543-37-9 C30H44O3 = 452.7 5mg QQ客服:1413575084
    灵芝酸S; Ganoderic acid S CFN99066 104759-35-5 C30H44O3 = 452.7 5mg QQ客服:3257982914
    灵芝酸TN; Ganoderic acid TN CFN90298 112430-64-5 C32H48O5 = 512.73 5mg QQ客服:2159513211
    灵芝酸X; Ganoderic acid X CFN92996 86377-53-9 C32H48O5 = 512.72 5mg QQ客服:215959384
    灵芝酸Jb; Ganoderic acid Jb CFN92997 112430-68-9 C30H46O4 = 470.68 5mg QQ客服:215959384

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