黄芪皂苷III

Astragaloside III

	产品编号	CFN99174
	CAS编号	84687-42-3
	分子式 = 分子量	C₄₁H₆₈O₁₄ = 784.97
	产品纯度	>=98%
	物理属性	Powder
	化合物类型	Triterpenoids
	植物来源	The roots of Astragalus membranaceus (Fisch.) Bunge
ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用

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产品名称	产品编号	CAS编号	包装	QQ客服
黄芪皂苷III	CFN99174	84687-42-3	10mg	QQ客服：215959384
黄芪皂苷III	CFN99174	84687-42-3	20mg	QQ客服：215959384
黄芪皂苷III	CFN99174	84687-42-3	50mg	QQ客服：215959384
黄芪皂苷III	CFN99174	84687-42-3	100mg	QQ客服：215959384

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ChemFaces的产品在许多优秀和顶级科学期刊中被引用

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089

Monash University Sunway Campus (Malaysia)

Medizinische Universit?t Wien (Austria)

Complutense University of Madrid (Spain)

Kyoto University (Japan)

Weizmann Institute of Science (Israel)

Universita' Degli Studi Di Cagliari (Italy)

Seoul National University of Science and Technology (Korea)

Mendel University in Brno (Czech Republic)

Cornell University (USA)

Aarhus University (Denmark)

University of Vigo (Spain)

Mahidol University (Thailand)

Washington State University (USA)

University Medical Center Mainz (Germany)

More...

Description:

Astragaloside III has anti-gastric ulcer effects, and exhibits strong growth-promoting effects in cultured GES-1 cells. Astragaloside III can effectively reduce cancer cell survival in vitro and inhibit the tumor growth in vivo, the potential mechanism is the induction of cell apoptosis signaling pathways, suggests that it provides a new therapeutic tool to treat breast cancer.

In vitro:

Fitoterapia. 2010 Jul;81(5):447-51.

Effects of cycloartane saponins from hairy roots of Astragalus membranaceus Bge., on human tumor cell targets.[Pubmed: 20060881]

For the first time three different natural compounds, isolated from hairy roots of Astragalus membranaceus, cultivated in airlift bioreactor were tested for their cytotoxic potential and apoptosis induction in a panel of human tumor cell lines.
METHODS AND RESULTS:
Root cultures, cultivated in bioreactor gave 18.5 g l(-1) dry wt roots with the highest astragaloside production in vitro up to now - 1.64% (astragaloside I), 1.12% (astragaloside II) and 1.08% (astragaloside III).
CONCLUSIONS:
In this manner the production in airlift bioreactor can be used as means of reliable supply of cycloartane saponins to extend the research to human clinical studies.

In vivo:

Afr. J. Tradit. Complem., 2015, 12(3):183-6.

Astragaloside III from Astragalus membranaceus antagonizes breast cancer growth[Reference: WebLink]

Astragaloside III has been used to treat different cancers; however their effect on breast cancer remains unknown.
METHODS AND RESULTS:
The present study examined the effects of Astragaloside III from Astragalus membranaceus on breast cancer cell lines in vitro as well as xenograft in vivo. The results showed that the Astragaloside III could effectively reduce cancer cell survival in vitro and inhibit the tumor growth in vivo. The potential mechanism is the induction of cell apoptosis signaling pathways.
CONCLUSIONS:
We believe that Astragaloside III provides a new therapeutic tool to treat breast cancer.

产品名称	产品编号	CAS编号	分子式 = 分子量	位单	联系QQ
环黄芪醇; Cycloastragenol	CFN99538	84605-18-5	C₃₀H₅₀O₅ = 490.71	20mg	QQ客服：215959384
黄芪甲苷IV; 黄芪皂苷Ⅳ; 黄芪甲苷; 黄芪甲甙; Astragaloside IV	CFN99171	84687-43-4	C₄₁H₆₈O₁₄ = 784.98	20mg	QQ客服：2159513211
黄芪甲苷 VII; Astrasieversianin VII	CFN90648	86764-11-6	C₄₃H₇₀O₁₅ = 827.01	10mg	QQ客服：3257982914
黄芪皂苷II; Astragaloside II	CFN99173	84676-89-1	C₄₃H₇₀O₁₅ = 827.02	20mg	QQ客服：2056216494
黄芪皂苷I; Astragaloside I	CFN99172	84680-75-1	C₄₅H₇₂O₁₆ = 869.1	20mg	QQ客服：3257982914
异黄芪皂苷I; Isoastragaloside I	CFN90977	84676-88-0	C₄₅H₇₂O₁₆ = 869.1	10mg	QQ客服：1457312923
黄芪皂苷III; Astragaloside III	CFN99174	84687-42-3	C₄₁H₆₈O₁₄ = 784.97	20mg	QQ客服：215959384
黄肉楠碱; Actein	CFN99864	18642-44-9	C₃₇H₅₆O₁₁ = 676.9	5mg	QQ客服：1457312923
升麻素苷; Cimicifugoside	CFN90481	66176-93-0	C₃₇H₅₄O₁₁ = 674.81	5mg	QQ客服：1413575084
26-脱氧升麻苷; 26-Deoxycimicifugoside	CFN90788	214146-75-5	C₃₇H₅₄O₁₀ = 658.8	5mg	QQ客服：215959384

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	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.2739 mL	6.3697 mL	12.7393 mL	25.4787 mL	31.8484 mL
5 mM	0.2548 mL	1.2739 mL	2.5479 mL	5.0957 mL	6.3697 mL
10 mM	0.1274 mL	0.637 mL	1.2739 mL	2.5479 mL	3.1848 mL
50 mM	0.0255 mL	0.1274 mL	0.2548 mL	0.5096 mL	0.637 mL
100 mM	0.0127 mL	0.0637 mL	0.1274 mL	0.2548 mL	0.3185 mL